Objective. To study variability of volumetric of the pulmonary nodules volumetry after manual correction of their contours.

Material and methods. Twenty-seven nodules uncircumscribed from the vascular structures and pleura were selected. A linear regression model was used to investigate the impact of the size of a nodule, the area of its contact with the adjacent structures on variability in results.

Results. The linear regression model based on contact area and nodule size can correctly predict volumetry variability.

Conclusion. Even after manual segmentation volumetry remain suitable method for size assessment of lung nodules. Segmentation should be made with the same person because of significant difference of interobserver and intraobserver variabilities.

Objective. To assess the immediate and long-term results of stenting of the unprotected left coronary artery (LCA) trunk in patients, by using different types of drug-eluting stents.

Material and methods. The follow-up covered 282 patients who had undergone stenting of the unprotected LCA trunk. The mean follow-up was 34.6 [33.9; 35.3] months. The patients were divided into groups according to the type of a first-, second-, and third-generation implanted stent.

Results. The incidence of adverse cardiovascular events in the patients of Group 1 was significantly higher than in those in Groups 2 and 3 (29 and 7.6%, p<0.0001). The incidence of thrombosis of first-generation stents (7.0%) was significantly higher than that of second- and third-generation ones (1.6%) (p=0.02). The incidence of adverse cardiovascular events was comparable between Groups 2 and 3, despite a shorter duration of dual antiplatelet therapy in the third-generation stent group. The absence of stent postdilatation in the LCA trunk is an independent risk factor for adverse prognosis.

Conclusion. The use of second- and third-generation stents along with changes in the technical aspects of stenting of the unprotected LCA trunk leads to a substantial reduction in the risk of adverse cardiovascular events and allows the indications for intervention to be expanded in this patient category.

Objective. To determine peculiarities when using microfocus cone beam computed tomography (micro-CBCT) and cone beam computed tomography (CBCT) to analyze the anatomy of the teeth and the quality of endodontic treatment.

Material and methods. Micro-CBCT and CBCT were experimentally used to examine 8 extracted tooth preparations before and after endodontic root canal treatment using different types of filling material.

Results. Micro-CBCT showed the high informative value of determining the type, nature, and quality of canal filling and diagnosed many cracks and accessory canals. According to the micro-CBCT findings, the tooth apexes were not filled; the lumen of the canals was unevenly and loosely filled with endodontic material; the passages of guttapercha points were well traced; the nature of the endodontic material was differentiated.

Conclusion. Micro-CBCT opens up new opportunities in dentistry with tooth volume visualization, allowing the minor and low-contrast details of the anatomical structure of the teeth to be seen on the X-ray image.

Objective. To assess whether radiographic criteria for proximal humeral head migration can be used as screening of damage to the rotator cuff after dislocation in patients over 45 years of age.

Material and methods. The study included the results of a follow-up of 101 patients after shoulder dislocation without signs of damage to the rotator cuff before injury. Damage to the rotator cuff was assessed using MRI, followed by a correlation analysis between the results of measuring the height of the subacromial space with radiography and MRI.

Results. Signs of cranial migration of the humeral head are detected statistically significantly more frequently in the group of older patients than in that of young ones (F=0.009; p<0.05). MRI study statistically significantly more often revealed signs of damage to the rotator cuff in the older patients than in the young ones (F=0.009; p<0.05). There was a high correlation between the humeral head migration index and the MRI measurements of the acromiohumeral interval (r=0.93, p<0.05).

Conclusion. The acromiohumeral index, as well as MRI, can be used as a criterion for rotator cuff injury. This study has shown that the older patients have a 19-fold higher risk for damage to the rotator cuff from a dislocated shoulder (95% CI 6.93–52.11). Thus, attention should be paid to the presence of radiographic signs of rotator cuff injury in all patients after dislocation of the shoulder.

Objective. To compare the values obtained for the measured diffusion coefficient (MDC) of brain gliomas with cell density and Ki-67 proliferative activity index and to study whether diffusion-weighted MRI (DWMRI) can be used in the preoperative evaluation of the grade of glial tumors.

Material and methods. Diffusion-weighted images of 39 patients with brain gliomas were studied. MDC, cell density, and Ki-67 proliferative activity index were calculated for each tumor. The correlation between MDC values, cell density, and Ki-67 proliferative activity index was analyzed.

Results. Comparison of the mean values for MDC revealed a significant difference between grades I–II and III–IV tumors. There were statistically significant differences in the mean Ki-67 index between different grades of gliomas. Evaluation of the correlation between MCD and Ki-67 proliferative activity index demonstrated moderate and strong inverse correlations for low- and high-grade tumors, respectively.

Conclusion. The procedure using DW-MRI along with MDC calculation can be used as an additional noninvasive method for the preoperative estimation of the grade and proliferative potential of brain gliomas.

The low incidence of nodular fistulas can create difficulties in diagnosis and timely treatment. This clinical observation describes the diagnosis of pneumonodular fistula in a female patient with tuberculosis at multiple sites as a complication of tuberculous mediastinitis. It describes the surgical treatment received by this patient and its outcome as an example of correct treatment policy for this complication.

The paper analyzes the data available in the foreign and Russian literature over the past 10 years on main radiodiagnostic techniques and approaches in case of ovarian space-occupying lesions, by using both ultrasonic color Doppler mapping and complex MRI approaches in combination with routine MRI, diffusion-weighted MRI studies, and follow-up contrast-enhanced MRI. It shows that only the comprehensive introduction of the above radiodiagnostic techniques can achieve the necessary sensitivity and specificity of diagnosis of ovarian tumors. The system for assessing the risk index for ovarian tumor malignancy is discussed, by taking into account the menopausal status, the tumor marker CA-125, and ultrasonographic findings. The paper presents the Adnexa MR scoring system based on the breast imaging-reporting and data system (BI-RADS) that gives schemes for calculating and analyzing the risk of ovarian tumor malignancy in terms of certain MR criteria.