Mesenchymal Cystic Hamartoma of the Lung
https://doi.org/10.20862/0042-4676-2023-104-4-264-269
Abstract
Mesenchymal cystic hamartoma, which was first described in 1986, is a very rare pulmonary pathology. To date, a little more than 20 cases have been registered in the literature. The disease usually has an asymptomatic course, but can potentially lead to severe pulmonary bleeding and even death. It has no specific radiological signs, therefore it is necessary to carry out differential diagnosis with other diseases, including malignant neoplasms. We present our own clinical observation of this pathology.
About the Authors
A. N. FedotovRussian Federation
Alexey N. Fedotov, Radiologist, Postgraduate, Chief of Chair of Radiology
ul. Barrikadnaya, 2/1, str. 1, Moscow, 125993
I. Е. Tuyrin
Russian Federation
Igor Е. Tuyrin, Dr. Med. Sc., Professor, Chief of Chair of Radiology Vice President
ul. Barrikadnaya, 2/1, str. 1, Moscow, 125993
References
1. Mark EJ. Mesenchymal cystic hamartoma of the lung. N Engl J Med. 1986; 315(20): 1255–9. http://doi.org/10.1056/NEJM198611133152004.
2. Hedlund GL, Bisset GS, Bove KE. Malignant neoplasms arising in cystic hamartomas of the lung in childhood. Radiology. 1989; 173(1): 77–9. http://doi.org/10.1148/radiology.173.1.2781034.
3. Mogi A, Miyanaga T, Kosaka T, et al. Thoracoscopic resection of a mesenchymal cystic hamartoma of the lung. Gen Thorac Cardiovasc Surg. 2011; 59(9): 619–22. http://doi.org/10.1007/s11748-010-0740-6.
4. Guo XW, Jia XD, Ji AD, et al. Large cystic-solid pulmonary hamartoma: a case report. World J Clin Cases. 2022; 10(8): 2650–6. http://doi.org/10.12998/wjcc.v10.i8.2650.
5. Erber R, Haller F, Hartmann A, et al. Prominent entrapment of respiratory epithelium in primary and metastatic intrapulmonary non-epithelial neoplasms: a frequent morphological pattern closely mimicking adenofibroma and other biphasic pulmonary lesions. Virchows Arch. 2020; 477: 195–205. http://doi.org/10.1007/s00428-020-02796-7.
6. Saadi MM, Barakeh DH, Husain S, et al. Large multicystic pulmonary сhondroid hamartoma in a child presenting as pneumothorax. Saudi Med J. 2015; 36: 487–9. http://doi.org/10.15537/smj.2015.4.10210.
7. Miura K, Hori T, Yoshizawa K, et al. Cystic pulmonary hamartoma. Ann Thorac Surg. 1990; 49: 828–9. http://doi.org/10.1016/0003-4975(90)90038-8.
8. Zhu H, Huang S, Zhou X. Mesenchymal cystic hamartoma of the lung. Ann Thorac Surg. 2012; 93(6): 145–7. http://doi.org/.1016/j.athoracsur.2011.12.041.
9. Souza Frederico F, Chen E. Mesenchymal cystic hamartoma of the lung. J Thorac Imaging. 2009; 24(1): 52–5. http://doi.org/10.1097/RTI.0b013e31818c8834.
10. Yuan L, Wang S, Wei J, et al. Mesenchymal cystic hamartoma of the lung: a case report. Medicine (Baltimore). 2022; 101(1): e28242. http://doi.org/10.1097/MD.0000000000028242.
11. Guo W, Zhao YP, Jiang YG, et al. Surgical treatment and outcome of pulmonary hamartoma: a retrospective study of 20-year experience. J Exp Clin Cancer Res. 2008; 27(1): 8. http://doi.org/10.1186/1756-9966-27-8.
Review
For citations:
Fedotov A.N., Tuyrin I.Е. Mesenchymal Cystic Hamartoma of the Lung. Journal of radiology and nuclear medicine. 2023;104(4):264-269. (In Russ.) https://doi.org/10.20862/0042-4676-2023-104-4-264-269