DIAGNOSTIC EFFICIENCY OF MULTIDETECTOR COMPUTED TOMOGRAPHY IN PATIENTS WITH TONGUE CANCER
https://doi.org/10.20862/0042-4676-2014-0-4-20-25
Abstract
Objective: to determine the capacities of multidetector computed tomography (MDCT) to diagnose tongue cancer.
Material and methods. Intravenous bolus contrast-enhanced MDCT was performed in 40 patients with tongue cancer diagnosed during complex clinical and instrumental examination. In all cases, the tumor had a structure of squamous cell carcinoma of varying grades. The results of MSCT were compared with the data of surgery and cytological and histological examinations. Tongue tumor accumulation of a contrast agent was qualitatively analyzed.
Results. In 38 (85%) patients, the tongue tumor actively accumulated the contrast agent and was clearly differentiated in the presence of unaffected portions of the tongue and other adjacent anatomical structures, such as mouth floor, oropharynx, and larynx. Only in two cases, the tumor failed to significantly accumulate the contrast agent, which was associated with that there were massive decay areas in its structure. The sensitivity, specificity, and accuracy of MDCT in the diagnosis of tongue cancer were 95, 80, and 87.5%, respectively. MDCT could reliably differentiate changes in tongue cancer from non-tumor diseases. The result of constructing the curve of diagnostic errors became the following values: the area under the curve was 0.875 and the P-value (Asymptotic Sig.) was 0.0001.
Conclusion. Intravenous bolus contrast-enhanced MDCT has a high diagnostic efficiency in identifying tongue cancer. The technique can establish the location of a tumor and to reveal the extent of the process to the nearby organs.
About the Authors
V. E. SinitsynRussian Federation
MD, PhD, DSc, Professor, Director of Center of Radiology of Federal Center of Treatment and Rehabilitation
Ivan’kovskoe shosse, 3, Moscow, 125367
V. S. Petrovichev
Russian Federation
Radiologist
ul. Baumanskaya, 17/1, Moscow, 105005
P. V. Vasil'ev
Russian Federation
MD, PhD, DSc, Radiologist
ul. Baumanskaya, 17/1, Moscow, 105005
E. A. Mershina
Russian Federation
MD, PhD, Associate Professor, Head of Department of Tomography of Center of Radiology of Federal Center of Treatment and Rehabilitation
Ivan’kovskoe shosse, 3, Moscow, 125367
References
1. Чиссов В.И., Старинский В.В. Злокачественные новообразования в России в 2010 году. М.; 2012. Chissov V.I., Starinskiy V.V. Malignant neoplasms in Russia in 2010. Moscow; 2012 (in Russian).
2. Давыдов М.И., Ганцев Ш.Х. Атлас по онкологии. М.: МИА; 2008: 43–4. Davydov M.I., Gantsev Sh.Kh. Atlas of Oncology. Moscow: MIA; 2008: 43–4 (in Russian).
3. Васильев П.В. Мультиспиральная рентгеновская компьютерная томография в диагностике рака гортани и гортаноглотки: Дис. ... д-ра мед. наук. М.; 2010. Vasil'ev P.V. Multidetector computed tomography in the diagnosis of cancer of the larynx and hypopharynx: Dr. med. sci. Diss. Moscow; 2010 (in Russian).
4. Кушхов О.А.-К. Клиническое значение мультиспиральной компьютерной томографии в выборе метода лечения и объема хирургического вмешательства при раке гортани: Дис. ... канд. мед. наук. М.; 2010. Kushkhov O.A.-K. Clinical value of multislice computed tomography in the considering treatment approaches and the amount of surgery for laryngeal cancer: PhD med. sci. Diss. Moscow; 2010 (in Russian).
5. Crespo Martínez C., Navarro Navarro M., Castro Copete M.C. Tumors of the oral cavity: the usefulness of dynamic CT. Radiologia. 2008; 50 (6): 509–16.
6. Daisne J.F., Duprez T., Weynand B. Tumor volume in pharyngolaryngeal squamous cell carcinoma: comparison at CT, MR imaging, and FDG PET and validation with surgical specimen. Radiology. 2004; 233 (1): 93–100.
7. Hadjiiski L., Mukherji S.K., Gujar S.K. Treatment response assessment of head and neck cancers on CT using computerized volume analysis. Am. J. Neuroradiol. 2010; 31 (9): 1744–51.
8. Kim S.H., Han M.H., Park S.W. Radiologic-pathologic correlation of unusual lingual masses: Part II: benign and malignant tumors. Korean. J. Radiol. 2001; 2 (1): 42–51.
9. Kim H.J., Lee B.J., Kim S.J. et al. Tongue abscess mimicking neoplasia. Am. J. Neuroradiol. 2006; 27 (10): 2202–3.
10. Scarfone C., Lavely W.C., Cmelak A.J. et al. Prospective feasibility trial of radiotherapy target definition for head and neck cancer using 3-demensional PET and CT imaging. J. Nucl. Med. 2004; 45 (4): 543–52.
Review
For citations:
Sinitsyn V.E., Petrovichev V.S., Vasil'ev P.V., Mershina E.A. DIAGNOSTIC EFFICIENCY OF MULTIDETECTOR COMPUTED TOMOGRAPHY IN PATIENTS WITH TONGUE CANCER. Journal of radiology and nuclear medicine. 2014;(4):20-25. (In Russ.) https://doi.org/10.20862/0042-4676-2014-0-4-20-25