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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rentrad</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник рентгенологии и радиологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of radiology and nuclear medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4676</issn><issn pub-type="epub">2619-0478</issn><publisher><publisher-name>Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20862/0042-4676-2014-0-4-20-25</article-id><article-id custom-type="elpub" pub-id-type="custom">rentrad-37</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>ДИАГНОСТИЧЕСКАЯ ЭФФЕКТИВНОСТЬ МУЛЬТИДЕТЕКТОРНОЙ КОМПЬЮТЕРНОЙ ТОМОГРАФИИ У ПАЦИЕНТОВ, СТРАДАЮЩИХ РАКОМ ЯЗЫКА</article-title><trans-title-group xml:lang="en"><trans-title>DIAGNOSTIC EFFICIENCY OF MULTIDETECTOR COMPUTED TOMOGRAPHY IN PATIENTS WITH TONGUE CANCER</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синицын</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinitsyn</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., профессор, директор Центра лучевой диагностики ЛРЦ</p><p>Иваньковское шоссе, 3, Москва, 125367</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, Professor, Director of Center of Radiology of Federal Center of Treatment and Rehabilitation</p><p>Ivan’kovskoe shosse, 3, Moscow, 125367</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петровичев</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrovichev</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-рентгенолог</p><p>ул. Бауманская, 17/1, Москва, 105005</p></bio><bio xml:lang="en"><p>Radiologist</p><p>ul. Baumanskaya, 17/1, Moscow, 105005</p></bio><email xlink:type="simple">petrovi4ev@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильев</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasil'ev</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., врач-рентгенолог</p><p>ул. Бауманская, 17/1, Москва, 105005</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, Radiologist</p><p>ul. Baumanskaya, 17/1, Moscow, 105005</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мершина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mershina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к. м. н., доцент, заведующая отделением томографии Центра лучевой диагностики ЛРЦ </p><p>Иваньковское шоссе, 3, Москва, 125367</p></bio><bio xml:lang="en"><p>MD, PhD, Associate Professor, Head of Department of Tomography of Center of Radiology of Federal Center of Treatment and Rehabilitation </p><p>Ivan’kovskoe shosse, 3, Moscow, 125367</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Лечебно-реабилитационный центр» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Center of Treatment and Rehabilitation, Ministry of Health of the RF</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ «Онкологический клинический диспансер № 1» Департамента здравоохранения г. Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Clinical Oncology Dispensary One, Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>27</day><month>02</month><year>2016</year></pub-date><volume>0</volume><issue>4</issue><fpage>20</fpage><lpage>25</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Синицын В.Е., Петровичев В.С., Васильев П.В., Мершина Е.А., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Синицын В.Е., Петровичев В.С., Васильев П.В., Мершина Е.А.</copyright-holder><copyright-holder xml:lang="en">Sinitsyn V.E., Petrovichev V.S., Vasil'ev P.V., Mershina E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.russianradiology.ru/jour/article/view/37">https://www.russianradiology.ru/jour/article/view/37</self-uri><abstract><p>Цель исследования – определить возможности мультидетекторной компьютерной томографии (МДКТ) в диагностике рака языка.</p><sec><title>Материал и методы</title><p>Материал и методы. МДКТ с внутривенным болюсным контрастированием выполнена 40 пациентам, у которых на основании результатов комплексного клинико-инструментального обследования был установлен диагноз рака языка. Во всех случаях опухоль имела строение плоскоклеточного рака разной степени дифференцировки. Результаты МДКТ сопоставлены с данными операций, цитологического и гистологического исследований. Выполнен качественный анализ накопления контрастного препарата опухолью языка.</p></sec><sec><title>Результаты</title><p>Результаты. У 38 (95%) пациентов опухоль языка активно накапливала контрастный препарат, четко дифференцировалась на фоне непораженных отделов языка и других окружающих анатомических структур: дна полости рта, ротоглотки, гортани. Только в 2 (5%) случаях заболевания опухоль достоверно не накапливала контрастный препарат, что было связано с наличием массивных зон распада в ее структуре. Чувствительность, специфичность и точность МДКТ в диагностике рака языка составили 95, 80 и 87,5% соответственно. МДКТ позволила надежно дифференцировать изменения при раке языка с заболеваниями неопухолевой природы. Результатом построения кривой диагностических ошибок стали следующие значения: площадь под ROC-кривой 0,875, p=0,0001.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to determine the capacities of multidetector computed tomography (MDCT) to diagnose tongue cancer.</p></sec><sec><title>Material and methods</title><p>Material and methods. Intravenous bolus contrast-enhanced MDCT was performed in 40 patients with tongue cancer diagnosed during complex clinical and instrumental examination. In all cases, the tumor had a structure of squamous cell carcinoma of varying grades. The results of MSCT were compared with the data of surgery and cytological and histological examinations. Tongue tumor accumulation of a contrast agent was qualitatively analyzed.</p></sec><sec><title>Results</title><p>Results. In 38 (85%) patients, the tongue tumor actively accumulated the contrast agent and was clearly differentiated in the presence of unaffected portions of the tongue and other adjacent anatomical structures, such as mouth floor, oropharynx, and larynx. Only in two cases, the tumor failed to significantly accumulate the contrast agent, which was associated with that there were massive decay areas in its structure. The sensitivity, specificity, and accuracy of MDCT in the diagnosis of tongue cancer were 95, 80, and 87.5%, respectively. MDCT could reliably differentiate changes in tongue cancer from non-tumor diseases. The result of constructing the curve of diagnostic errors became the following values: the area under the curve was 0.875 and the P-value (Asymptotic Sig.) was 0.0001.</p></sec><sec><title>Conclusion</title><p>Conclusion. Intravenous bolus contrast-enhanced MDCT has a high diagnostic efficiency in identifying tongue cancer. The technique can establish the location of a tumor and to reveal the extent of the process to the nearby organs.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>мультидетекторная компьютерная томография</kwd><kwd>рак языка</kwd><kwd>опухоль языка</kwd></kwd-group><kwd-group xml:lang="en"><kwd>multidetector computed tomography</kwd><kwd>tongue cancer</kwd><kwd>tongue tumor</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Чиссов В.И., Старинский В.В. Злокачественные новообразования в России в 2010 году. М.; 2012. Chissov V.I., Starinskiy V.V. Malignant neoplasms in Russia in 2010. Moscow; 2012 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Чиссов В.И., Старинский В.В. Злокачественные новообразования в России в 2010 году. М.; 2012. 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