Experience in Using 99mTc-Technephyt Esophageal Transit Scintigraphy for Assessing Pneumatic Dilation Outcome in Patients with Achalasia Cardia
https://doi.org/10.20862/0042-4676-2024-105-3-120-129
Abstract
Objective: to show the possibility of using 99mTc-technephyt esophageal transit scintigraphy (ETS) to assess the effect of cardiodilation in patients with achalasia cardia.
Material and methods. We examined 7 patients (6 males and 1 female) aged 44–73 years (mean age 57.8 years) diagnosed with achalasia cardia, who were treated in Department of Thoracic Surgery No. 2 at Republican Clinical Hospital from June 2022 to January 2023. The disease duration before admission to the hospital ranged from 2 to 17 years (mean 9.2 years).
Results. The analysis of ETS results showed a decreased radiopharmaceutical residual activity percentage in cardia for all patients after treatment compared with the initial data. It indicated a positive effect of cardiodilation and coincided with X-ray examination data. The obtained results demonstrate the possibility of ETS using and its practical significance to assess the effect of therapeutic measures, in particular cardiodilation, in patients with achalasia cardia.
Conclusion. Performed according to the described protocol, ETS is a physiological and safe method for both the diagnosis of achalasia and the subsequent assessing therapeutic effect, including cardiodilation, myotomy, conservative treatment, and long-term dynamic monitoring. It is a physiological and safe procedure, which can be recommended in cases of difficulties in evaluating the esophageal function by X-ray, endoscopic and manometric methods or when their use is impossibile.
About the Authors
R. A. BashirovRussian Federation
Rustem A. Bashirov, Assistant Professor, Academicians Pavlov and Krotkov Chair of Radiotherapy and Radiology; Assistant Professor, Chair of Oncology, Radiation Diagnostics and Radiation Therapy; Radiologist, Department of Radiology
Vtoroy Botkinskiy proezd, 7, Moscow, 125284
ul. Butlerova, 49, Kazan, 420012
Orenburgskiy trakt, 138, Kazan, 420064
A. I. Shelepova
Russian Federation
Angelina I. Shelepova, Resident, Chair of Oncology, Radiation Diagnostics and Radiation Therapy
ul. Butlerova, 49, Kazan, 420012
L. E. Samoilenko
Russian Federation
Lyudmila E. Samoilenko, Dr. Med. Sc., Professor, Academicians Pavlov and Krotkov Chair of Radiotherapy and Radiology
Vtoroy Botkinskiy proezd, 7, Moscow, 125284
S. A. Ryzhkin
Russian Federation
Sergey A. Ryzhkin, Dr. Med. Sc., Associate Professor, Corresponding Member of Academy of Sciences of the Republic of Tatarstan, Chief of Academicians Pavlov and Krotkov Chair of Radiotherapy and Radiology; Professor, Chair of General Hygiene; Professor, Chair of Medical Physics, Institute of Physics
Vtoroy Botkinskiy proezd, 7, Moscow, 125284
ul. Butlerova, 49, Kazan, 420012
ul. Kremlevskaya, 18, korp. 1, Kazan, 420008
B. M. Sharafutdinov
Russian Federation
Bulat M. Sharafutdinov, Cand. Med. Sc., Head of Department of Endovascular Surgical Methods of Diagnosis and Treatment, Medical and Sanitary Unit; Assistant Professor, Department of Cardiology, Endovascular and Cardiovascular Surgery
ul. Kremlevskaya, 18, korp. 1, Kazan, 420008
ul. Butlerova, 36, Kazan, 420012,
A. F. Yusupova
Russian Federation
Alsu F. Yusupova, Cand. Med. Sc., Associate Professor, Chair of Oncology, Radiation Diagnostics and Radiation Therapy
ul. Butlerova, 49, Kazan, 420012
L. F. Ziganshina
Russian Federation
Lilia F. Ziganshina, Cand. Med. Sc., Assistant Professor, Chair of Oncology, Radiation Diagnostics and Radiation Therapy; Head of Department of Radiology
ul. Butlerova, 49, Kazan, 420012
Orenburgskiy trakt, 138, Kazan, 420064
B. A. Magomedov
Russian Federation
Bulyamin A. Magomedov, Thoracic Surgeon
Orenburgskiy trakt, 138, Kazan, 420064
A. I. Kukushkin
Russian Federation
Andrey I. Kukushkin, Head of Department of Thoracic Surgery No. 2, Junior Researcher
Orenburgskiy trakt, 138, Kazan, 420064
V. Yu. Matveev
Russian Federation
Valeriy Yu. Matveev, Cand. Med. Sc., Head of Department of Thoracic Surgery No. 1, Leading Researcher
Orenburgskiy trakt, 138, Kazan, 420064
D. R. Bashirov
Russian Federation
Damir R. Bashirov, Radiologist
Sadykov City Clinical Hospital No. 7
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Review
For citations:
Bashirov R.A., Shelepova A.I., Samoilenko L.E., Ryzhkin S.A., Sharafutdinov B.M., Yusupova A.F., Ziganshina L.F., Magomedov B.A., Kukushkin A.I., Matveev V.Yu., Bashirov D.R. Experience in Using 99mTc-Technephyt Esophageal Transit Scintigraphy for Assessing Pneumatic Dilation Outcome in Patients with Achalasia Cardia. Journal of radiology and nuclear medicine. 2024;105(3):120-129. (In Russ.) https://doi.org/10.20862/0042-4676-2024-105-3-120-129