Predicting the Success of Emergency Surgical Treatment of Acute Massive Pulmonary Embolism Based on the Results of Multislice Computed Tomography
https://doi.org/10.20862/0042-4676-2019-100-6-363-371
Abstract
Objective – to assess the informativeness of multisclice computed tomography (MSCT) angiopulmonography in the assessment of peripheral blood flow and to determine the prognostic role of angiographic massiveness and volume of preserved peripheral blood flow as predictors of success of emergency surgical treatment of acute massive pulmonary embolism (PE).
Material and methods. The article presents the results of 7-year work for the period from March 2012 to September 2019, which included a pilot retrospective stage (analysis of the results of 264 MSCT procedures with contrast enhancement for acute PE in patients aged 32 to 69 years for the period 2012–2013) and prognostic practical work (the second stage, analysis of the results of 974 MSCT procedures with contrast enhancement in patients aged 25 to 78 years for the period 2013–2019).
Results. The obtained results and statistical dependences proved the influence of the saved volume of peripheral arterial pulmonary blood flow on the outcome of surgical treatment. The use of this indicator as an MSCT predictor reduced the hospital mortality rate from 7.2% to 3.5%. The analysis of the influence of the initial angiographic massiveness of PE on the outcome of surgical treatment has not been confirmed.
Conclusion. According to the results of the study, we recommend the inclusion of segmental arterial pulmonary blood flow analysis by MSCT with contrast enhancement in the algorithm of preoperative examination of patients with acute massive pulmonary embolism in case of emergency surgical treatment.
About the Authors
T. N. TrofimovaRussian Federation
Tat'yana N. Trofimova, Dr. Med. Sc., Professor of Radiology Chair
ul. L'va Tolstogo, 6-8, St. Petersburg, 197022
M. B. Sukhova
Russian Federation
Marina B. Sukhova, Cand. Med. Sc., Head of Department of Radiological Diagnostics
ul. Vaneeva, 209, Nizhny Novgorod, 603950
References
1. Medvedev A.P., Deryabin R.A., Nemirova S.V., Demarin O.I., Pichugin V.V., Penknovich A.A. et al. Surgical treatment of massive pulmonary embolism in elderly and senile patients. Medical Almanach. 2013; 4: 67–71 (in Russ.).
2. Savel’ev V.S. Phlebology: Guide for doctors. Moscow: Meditsina; 2001 (in Russ.).
3. Mahmud E., Madani M.M., Kim N.H., Poch D., Ang L., Behnamfar O. et al. Chronic thromboembolic pulmonary hypertension: evolving therapeutic approaches for operable and inoperable disease. J. Am. Coll. Cardiol. 2018; 71 (21): 2468–86. DOI: 10.1016/j.jacc.2018.04.009
4. Medvedev A.P., Nemirova S.V., Pichugin V.V., Kudykin M.N., Deryabin R.A. Surgical treatment of recurrent massive pulmonary embolism: indications and results. Journal of Venous Disorders. 2011; 5 (1): 41–5 (in Russ.).
5. Sista A.K., Kuo W.T., Schiebler M., Madoff D.C. Stratification, imaging, and management of acute massive and submassive pulmonary embolism. Radiology. 2017; 284 (1): 5–24. DOI: 10.1148/radiol.2017151978
6. Liu M., Guo X., Zhu L., Zhang H., Hou Q., Guo Y. et al. Computed tomographic pulmonary angiographic findings can predict short-term mortality of saddle pulmonary embolism: a retrospective multicenter study. J. Comp. Ass. Tomogr. 2016; 40 (3): 327–34. DOI: 10.1097/RCT.0000000000000373
7. Jimenez D., Aujesky D., Moores L. Simplification of the pulmonary embolism severity index for prognostication in patients with acute symptomatic pulmonary embolism. Arch. Intern. Med. 2010; 170 (15): 1383–9. DOI: 10.1001/ archinternmed.2010.199
8. Mean M., Tritschler T., Limacher A., Breault S., Rodondi N., Aujesky D., Qanadli S.D. Association between computed tomography obstruction index and mortality in elderly patients with acute pulmonary embolism: a prospective validation study. PLoS ONE. 2017; 12 (6). DOI: 10.1371/journal.pone.0179224
9. Lishmanov J.B., Pan'kova A.N., Zavadovsky K.V. To the question about the causes of dissociation between the level of arterial thromboembolism of the pulmonary bed and the degree of right ventricular dysfunction. Russ. Cardiol. J. 2012; 3: 28–32.
10. Rudik N.V., Myagkov A.P., Myagkov S.A., Sementsova A.S., Nakonechnyy S.Yu. The possibilities of computed tomography in the diagnosis of angiopulmonography pulmonary embolism. Modern Medical Technology. 2014; 2: 116–21 (in Russ.).
11. Miller G. The diagnosis and management of massive pulmonary embolism. Brit. J. Surg. 1972; 59 (10): 837–9. DOI: 10.1002/bjs.1800591025
12. Yoshimi S., Tanabe N., Masuda M., Sakao S., Uruma T., Shimizu H. et al. Survival and quality of life for patients with peripheral type chronic thromboembolic pulmonary hypertension. Circ. J. 2008; 72 (6): 958–65.
13. Savel'evV.S., Yablokov K.G., Kirienko E.G. Pulmonary embolism. Moscow: Meditsina; 1979: 264 (in Russ.).
14. Trofimova T.N., Khalikov A.D., Karpenko A.K. Radiation anatomy: Guide for physicians. St. Petersburg; 2005 (in Russ.).
15. Sinel'nikov R.D. Atlas of human anatomy. Moscow: Meditsina; 1996; 2: 157–60 (in Russ.).
Review
For citations:
Trofimova T.N., Sukhova M.B. Predicting the Success of Emergency Surgical Treatment of Acute Massive Pulmonary Embolism Based on the Results of Multislice Computed Tomography. Journal of radiology and nuclear medicine. 2019;100(6):363-371. (In Russ.) https://doi.org/10.20862/0042-4676-2019-100-6-363-371