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Invasive Mucormycosis with Lung Involvement in a Female Patient with Aplastic Anemia

https://doi.org/10.20862/0042-4676-2019-100-4-215-221

Abstract

Mucormycosis is an infection caused by one of several types of mold. Invasive mucormycosis is the most aggressive, rapidly progressive fungal infection. The disease is characterized by high attributable mortality. The early and accurate diagnosis of invasive mucormycosis determines the choice of an adequate therapeutic policy, by improving the prognosis of the disease. The method of choice for diagnosing pulmonary mucormycosis is computed tomography that allows accurate determination of the location and extent of the lesion, the state of the lung parenchyma, and the presence of concomitant complications. The paper describes a clinical case of damage to the lung and skin in invasive mucormycosis in a 28-year-old woman with aplastic anemia. The case is of interest due to a larger number of immunocompromised patients, especially those susceptible to the disease.

About the Authors

Zh. V. Sheikh
S.P. Botkin City Clinical Hospital, Department of Health of the City of Moscow
Russian Federation
Dr. Med. Sc., Professor, Head of Сomputed Tomography Department


I. E. Tyurin
Russian Medical Academy of Continuous Professional Education, Ministry of Health of the Russian Federation
Russian Federation
Dr. Med. Sc., Professor, Chief of Radiology Chair


A. I. Sinopal’nikov
Russian Medical Academy of Continuous Professional Education, Ministry of Health of the Russian Federation
Russian Federation
Dr. Med. Sc., Professor, Chief of Pulmonology Chair


A. V. Arablinskiy
S.P. Botkin City Clinical Hospital, Department of Health of the City of Moscow; I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Russian Federation
Dr. Med. Sc., Professor, Head of Radiodiagnosis Department


T. D. Safonova
Russian Medical Academy of Continuous Professional Education, Ministry of Health of the Russian Federation
Russian Federation
Clinical Resident of Radiology Chair


E. V. Fedyaeva
Russian Medical Academy of Continuous Professional Education, Ministry of Health of the Russian Federation
Russian Federation
Clinical Resident of Radiology Chair


O. B. Murav’ev
S.P. Botkin City Clinical Hospital, Department of Health of the City of Moscow
Russian Federation
Cand. Med. Sc., Head of Department of Anesthesiology and Resuscitation for Infectious Patients


S. N. Shvayko
S.P. Botkin City Clinical Hospital, Department of Health of the City of Moscow
Russian Federation
Cand. Med. Sc., Head of Pulmonology Department


References

1. Samsonova M.V., Сhernyaev А.L., Lebedin Yu.S., Mikhaylichenko К.Yu., Polivanova A.E. Mucormycosis of the lungs. Russian Pulmonology. 2018; 28 (2): 243–7 (in Russ.). DOI: 10.18093/0869-0189-2018-28-2-243-247

2. Klimko N.N. Mycoses: diagnosis and treatment. Guide for doctors. Moscow: WGGroup; 2008 (in Russ.).

3. Skiada A., Pagano L., Groll A., Zimmerli S., Dupont B., Lagrou K. Zygomycosis in Europe: analysis of 230 cases accrued by the registry of the European Confederation of Medical Mycology (ECMM) Working Group on Zygomycosis between 2005 and 2007. Clin. Microbiol. Infect. 2011; 17 (12): 1859–67. DOI: 10.1111/j.1469-0691.2010.03456

4. Lanternier F., Dannaoui E., Morizot G., Elie C., Garcia-Hermoso D., Huerre M. A global analysis of mucormycosis in France: the Retro Zygo Study (2005–2007). Clin. Infect. Dis. 2012; 54 (Suppl. 1): 35–43. DOI: 10.1093/cid/cir880

5. Meis J.F., Chakrabarti A. Changing epidemiology of an emerging infection: zygomycosis. Clin. Microbiol. Infect. 2009; 15 (Suppl. 5): 10–4. DOI: 10.1111/j.1469-0691.2009.02973

6. Khostelidi S.N., Shapochnik А.P., Monina Yu.V., Zaytsev S.B., Bogomolova T.S., Klimko N.N. Disseminated mucormycosis by a patient with acute lymphoblastic leukemia (clinical case). Journal Infectology. 2013; 5 (3): 74–9 (in Russ.). DOI: 10.22625/2072-6732-2013-5-3-74-79

7. Sheykh Zh.V., Zakharova Е.V., Dunaev А.P. CT in the diagnosis of pulmonary lesions by granulomatosis with polyangiitis. Moscow: Kraft+; 2017 (in Russ.).]


Review

For citations:


Sheikh Zh.V., Tyurin I.E., Sinopal’nikov A.I., Arablinskiy A.V., Safonova T.D., Fedyaeva E.V., Murav’ev O.B., Shvayko S.N. Invasive Mucormycosis with Lung Involvement in a Female Patient with Aplastic Anemia. Journal of radiology and nuclear medicine. 2019;100(4):215-221. (In Russ.) https://doi.org/10.20862/0042-4676-2019-100-4-215-221

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ISSN 0042-4676 (Print)
ISSN 2619-0478 (Online)