Radiologic diagnosis of pulmonary metastases of uterine choriocarcinoma
https://doi.org/10.20862/0042-4676-2018-99-6-326-330
Abstract
The article describes a rare case of metastatic pulmonary choriocarcinoma manifested with hemoptysis. Obstacles and pitfalls of the diagnosis of uterine choriocarcinoma with atypical manifestation were discussed. The patterns of pulmonary metastases of uterine choriocarcinoma and contribution of cross-sectional imaging modalities to diagnostic work-up were described. For the first time diffusion weighted magnetic resonance imaging of the chest was used for the follow-up examination and diagnosis of the recurrence of the disease.
This case is of interest due to unusual clinical and radiological presentation of uterine choriocarcinoma. The article is aimed to radiologists to be familiar with this disease to provide its early diagnosis and timely treatment.
About the Authors
A. V. SudarkinaRussian Federation
Anna V. Sudarkina - Radiologist, Assistant Professor of Ohair of Radiology.
Vladimirovskiy spusk, 2а, Novosibirsk, 630003; Krasnyy Prospekt, 52, Novosibirsk, 630091
A. P. Dergilev
Russian Federation
Dr. Med. Sc., Professor, Head of Department of Radiology; Chief of Chair of Radiology.
Vladimirovskiy spusk, 2а, Novosibirsk, 630003; Krasnyy Prospekt, 52, Novosibirsk, 630091
Yu. V. Chikinev
Russian Federation
Dr. Med. Sc., Professor, Chief of Chair of Hospital and Pediatric Surgery.
Krasnyy Prospekt, 52, Novosibirsk, 630091
E. A. Drobyazgin
Russian Federation
Dr. Med. Sc., Professor of Chair of Hospital and Pediatric Surgery, Thoracic Surgeon.
Krasnyy Prospekt, 52, Novosibirsk, 630091
V. I. Kochura
Russian Federation
Cand. Med. Sc., Associate Professor of Chair of Radiology, Head of Department of Roentgenology.
Krasnyy Prospekt, 52, Novosibirsk, 630091
N. A. Gorbunov
Russian Federation
Cand. Med. Sc., Associate Professor of Chair of Radiology.
Krasnyy Prospekt, 52, Novosibirsk, 630091
References
1. Meshcheryakova L.A. Trophoblastic disease. Opukholi Zhenskoy Reproduktiv-noy Sistemy (Tumors of Female Reproductive System). 2014; 4: 74-82 (in Russ.).
2. Mangla M., Singla D., Kaur H., Shar-ma S. Unusual clinical presentations of choriocarcinoma: a systematic review of case reports. TaiwanJ. Obstet. Gynecol. 2017; 56(1): 1-8. DOI: 10.1016/j.tjog.2015.05.011
3. Tyurin I.E. Radiologic diagnosis of metastatic lung disease. Atmosfera. Pul'monologiya i Allergologiya (Atmosphere. Pulmonology and Allergology). 2011; 1: 22-8 (in Russ.).
4. Seo J.B., Im J.G., Goo J.M., Chung M.J., Kim M.Y. Atypical pulmonary metastases: spectrum of radiologic findings. Radiographics. 2001; 21 (2): 403-17. DOI: 10.1148/radiographics.21.2.g01mr17403
5. Kani K.K., Lee J.H., Dighe M., Mo-shiri M., Kolokythas O., Dubinsky T. Gestatational trophoblastic disease: multimodality imaging assessment with special emphasis on spectrum of abnormalities and value of imaging in staging and management of disease. Curr. Probl. Diagn. Radiol. 2012; 41 (1): 1-10. DOI: 10.1067/j.cpradiol.2011.06.002
6. Dhanda S., Ramani S., Thakur M. Gestational trophoblastic disease: a multimodality imaging approach with impact on diagnosis and management. Radiol. Res. Pract. 2014; 2014: 842751. DOI: 10.1155/2014/842751
7. Shaaban A.M., Rezvani M., Haro-un R.R., Kennedy A.M., Elsayes K.M., Olpin J.D. et al. Gestational trophoblastic disease: clinical and imaging features. Radiographics. 2017; 37: 681-700. DOI: 10.1148/rg.2017160140
8. Chang T.C., Yen T.C., Li Y.T., Wu Y.C., Chang Y.C., Ng K.K. et al. The role of 18F-fluorodeoxyglucose positron emission tomography in gestational trophoblastic tumours: a pilot study. Eur. J. Nucl. Med. Mol. Imaging. 2006; 33 (2): 156-63. DOI: 10.1007/s00259-005-1873-1
Review
For citations:
Sudarkina A.V., Dergilev A.P., Chikinev Yu.V., Drobyazgin E.A., Kochura V.I., Gorbunov N.A. Radiologic diagnosis of pulmonary metastases of uterine choriocarcinoma. Journal of radiology and nuclear medicine. 2018;99(6):326-330. (In Russ.) https://doi.org/10.20862/0042-4676-2018-99-6-326-330