FUNCTIONAL AND DIFFUSION-TENSOR MAGNETIC RESONANCE IMAGING IN DETECTION OF ALZHEIMER’S DISEASE ON EARLY STAGES
https://doi.org/10.20862/0042-4676-2017-98-6-320-326
Abstract
Alzheimer's disease (AD) is the most common form of dementia among neurodegenerative diseases. New advanced methods of magnetic resonance imaging, such as functional (fMRI) and diffusiontensor imaging (DT-MRI), can evaluate changes in brain matter of AD at the microstructural and functional levels and can be used in the diagnostics of this pathological process on early stages of cognitive impairment. In this review, a literature search was made in electronic databases and scientific libraries of PubMed, Medscape, Elsiever, Cyberleninka. The review highlighted the merits and demerits of fMRI and DT-MRI, the clinical application of this methods in diagnosis of AD on early stage were also assessed.
About the Authors
V. E. SinitsynRussian Federation
MD, PhD, DSc, Professor, Director of Diagnostic Radiology Center of FCTR.
Ivan’kovskoe shosse, 3, Moscow, 125367; Ul. Barrikadnaya, 2/1, Moscow, 125993
V. N. Gridin
Russian Federation
Dr. Tech. Sc., Professor, Scientific Director.
Ul. Marshala Biryuzova, 7a, Odintsovo,143000
E. M. Perepelova
Russian Federation
MD, PhD, Head of Department of Radiology.
Ul. Trubetskaya, 8, stroenie 2, Moscow, 119991
M. S. Merkulova
Russian Federation
Postgraduate.
Ul. Barrikadnaya, 2/1, Moscow, 125993
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Review
For citations:
Sinitsyn V.E., Gridin V.N., Perepelova E.M., Merkulova M.S. FUNCTIONAL AND DIFFUSION-TENSOR MAGNETIC RESONANCE IMAGING IN DETECTION OF ALZHEIMER’S DISEASE ON EARLY STAGES. Journal of radiology and nuclear medicine. 2017;98(6):320-326. (In Russ.) https://doi.org/10.20862/0042-4676-2017-98-6-320-326