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FUNCTIONAL AND DIFFUSION-TENSOR MAGNETIC RESONANCE IMAGING IN DETECTION OF ALZHEIMER’S DISEASE ON EARLY STAGES

https://doi.org/10.20862/0042-4676-2017-98-6-320-326

Abstract

Alzheimer's disease (AD) is the most common form of dementia among neurodegenerative diseases. New advanced methods of magnetic resonance imaging, such as functional (fMRI) and diffusiontensor imaging (DT-MRI), can evaluate changes in brain matter of AD at the microstructural and functional levels and can be used in the diagnostics of this pathological process on early stages of cognitive impairment. In this review, a literature search was made in electronic databases and scientific libraries of PubMed, Medscape, Elsiever, Cyberleninka. The review highlighted the merits and demerits of fMRI and DT-MRI, the clinical application of this methods in diagnosis of AD on early stage were also assessed.

About the Authors

V. E. Sinitsyn
Federal Center of Treatment and Rehabilitation, Ministry of Health of the Russian Federation; Russian Medical Academy of Continuous Professional Education, Ministry of Health of the Russian Federation
Russian Federation

MD, PhD, DSc, Professor, Director of Diagnostic Radiology Center of FCTR.

Ivan’kovskoe shosse, 3, Moscow, 125367; Ul. Barrikadnaya, 2/1, Moscow, 125993



V. N. Gridin
Center of Information Technologies in Design, Russian Academy of Sciences
Russian Federation

Dr. Tech. Sc., Professor, Scientific Director.

Ul. Marshala Biryuzova, 7a, Odintsovo,143000



E. M. Perepelova
I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Russian Federation

MD, PhD, Head of Department of Radiology.

Ul. Trubetskaya, 8, stroenie 2, Moscow, 119991



M. S. Merkulova
Russian Medical Academy of Continuous Professional Education, Ministry of Health of the Russian Federation
Russian Federation

Postgraduate.

Ul. Barrikadnaya, 2/1, Moscow, 125993



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Review

For citations:


Sinitsyn V.E., Gridin V.N., Perepelova E.M., Merkulova M.S. FUNCTIONAL AND DIFFUSION-TENSOR MAGNETIC RESONANCE IMAGING IN DETECTION OF ALZHEIMER’S DISEASE ON EARLY STAGES. Journal of radiology and nuclear medicine. 2017;98(6):320-326. (In Russ.) https://doi.org/10.20862/0042-4676-2017-98-6-320-326

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ISSN 0042-4676 (Print)
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