Preview

Journal of radiology and nuclear medicine

Advanced search

X-ray semiotics of endocrine ophthalmopathy. Part 1. Extraocular muscles and orbital cellular tissue

https://doi.org/10.20862/0042-4676-2016-97-3-133-142

Abstract

Objective: to examine the state of the extraocular muscles and orbital cellular tissue of patients with different clinical forms of endocrine ophthalmopathy.

Material and methods. The study involved 294 patients (559 orbits) with endocrine ophthalmopathy. In 87 of them (174 orbits), thyrotoxic exophthalmos was diagnosed, in 172 (343 orbits) – edematous exophthalmos (with myogenic type in 30 patients, lipogenic type in 46, mixed type in 96 patients), in 35 patients (42 orbits) – endocrine myopathy.

Results. The article presents the volumes of extraocular muscles and orbital cellular tissue in patients with different forms of endocrine ophthalmopathy. The density of the muscles and orbital cellular tissue was studied in details in those groups of patients. The results show that increase of extraocular muscles volume is greater than increase of orbital cellular tissue volume, and have specific features for each form of endocrine ophthalmopathy.

Conclusion. We detected significant quantitative differences in orbit soft tissue volume in patients with endocrine ophthalmopathy. That confirms the feasibility of allocating of three forms of endocrine ophthalmopathy and explains its variative clinical presentations.

About the Authors

O. Yu. Yatsenko
Russian Medical Academy of Postgraduate Education, Ministry of Health of the RF, ul. Barrikadnaya, 2/1, Moscow, 125993, Russian Federation
Russian Federation
MD, PhD, DSc, Associate Professor of Department of Ophthalmology


I. E. Tyurin
Russian Medical Academy of Postgraduate Education, Ministry of Health of the RF, ul. Barrikadnaya, 2/1, Moscow, 125993, Russian Federation
Russian Federation

MD, PhD, DSc, Professor, Chief of Department of Radiation Diagnosis, Radiotherapy and Medical Physics



References

1. Henzen C. Hyperthyroidism – differential diagnosis and therapy. Praxis. 2003; 92 (1–2): 18–24.

2. Brovkina A.F., Yurovskaya N.N., Tyutyunnikova A. M. Classification and clinical features endocrine ophthalmopathy. Vestnik Oftal’mologii [Annals of Ophthalmology]. 1983; 1: 40–3 (in Russ.).

3. Brovkina A.F., Karmazanovskiy G.G., Yatsenko O.Yu., Moslekhi Sh. Optic nerve condition at the edematous exophthalmos complicated by optical neuropathy (computed tomography). Meditsinskaya Vizualizatsiya [Medical Visualization]. 2008; 3: 74–7 (in Russ.).

4. Schultz S., Maun L., Black E. Thyroid ophthalmopathy. Oftal’- mologicheskie Vedomosti [Ophthalmology Statements]. 2012; 5 (2): 20–30 (in Russ.).

5. Zakrzewski P.A., Weis E., White V.A., Rootman J. Intracellular extraocular muscle light-and heavy-chain deposition disease contributing to compressive optic neuropathy in a patient with preexisting Graves' orbitopathy. Ophthalmologica. 2010; 224: 59–62.

6. Chan L.L., Tan H.E., Fook-Chong S., Teo T.H., Lim L.H., Seah L.L. Graves ophthalmopathy: the bony orbit in optic neuropathy, its apical angular capacity, and impact on prediction of risk. Am. J. Neuroradiol. 2009; 30 (3): 597–602.

7. Liao S.L., Huang S.W. Correlation of retrobulbar volume change with resected orbital fat volume and proptosis reduction after fatty decompression for graves ophthalmopathy. m. J. Ophthalmol. 2011; 151 (3): 465–9.

8. Hu W.D., Annunziata C.C., Chokthaweesak W., Korn B.S., Levi L., Granet D.B., Kikkawa D.O. Radiographic analysis of extraocular muscle volumetric changes in thyroid- related orbitopathy following orbital decompression. Ophthal. Plast. Reconstr. Surg. 2010; 26 (1): 1–6.

9. Gonc5alves A.C., Silva L.N., Gebrim E.M., Monteiro M.L. Quantification of orbital apex crowding for screening of dysthyroid optic neuropathy using multidetector CT. Am. J. Neuroradiol. 2012; 33 (8): 1602–7.

10. Aydin K., Guven K., Sencer S., Cikin A., Gul A., Minareci O. A new MRI method for the quantitative evaluation of extraocular muscle size in thyroid ophthalmopathy. Neuroradiology. 2003; 45 (3): 184–7.

11. Yatsenko O.Yu. Space-topographical and structural changes in the soft tissue at the top of the orbit optic neuropathy at patients from edematous exophthalmos. Oftal’mologiya[Ophthalmology]. 2014; 11 (2): 48–54 (in Russ.).

12. Regensburg N.I., Wiersinga W.M., Berendschot T.T., Saeed P., Mourits M.P. Densities of orbital fat and extraocular muscles in graves orbitopathy patients and controls. Ophthal. Plast. Reconstr. Surg. 2011; 27 (4): 236–40.

13. Hu W.D., Annunziata C.C., Chokthaweesak W., Korn B.S., Levi L., Granet D.B., Kikkawa D.O. Radiographic analysis of extraocular muscle volumetric changes in thyroid- related orbitopathy following orbital decompression. Ophthal. Plast. Reconstr. Surg. 2010; 26 (1):1–6.

14. Kamer L., Noser H., Schramm A., Hammer B., Kirsch E. Anatomybased surgical concepts for individualized orbital decompression surgery in graves orbitopathy. I. Orbital size and geometry. Ophthal. Plast. Reconstr. Surg. 2010; 26 (5): 348–52.

15. Brovkina A.F., Yatsenko O.Yu., Aubakirova A.S. Methods of calculating the volume of the orbital cellular tissue, removed during decompressive surgery in patients with endocrine ophthalmopathy. Vestnik Oftal’mologii [Annals of Ophthalmology]. 2009; 125 (3): 24–7 (in Russ.).

16. Ben Simon G.J., Syed H.M., Douglas R., Mc Cann J.D., Goldberg R.A. Extraocular muscle enlargement with tendon involvement in thyroid- associated orbitopathy. Am. J. Ophthalmol. 2004; 137 (6): 1145–7.

17. Brovkina A.F., Karmazanovskiy G.G., Yatsenko O.Yu. The normal volume of the bone orbit and its soft tissues. Meditsinskaya Vizualizatsiya [Medical Visualization]. 2006; 6: 94–8 (in Russ.).

18. Forbes G., Gorman C.A., Brennan M.D., Gehring D.G., Ilstrup D.M., Earnest F. Ophthalmopathy of Graves' disease: Computerized volume measurements of the orbital fat and muscle. Am. J. Neuroradiol. 1986; 7 (4): 651–6.

19. Nishida Y., Tian S., Isberg B., Hayashi O., Tallstedt L., Lennerstrand G. Significance of orbital fatty tissue for exophthalmos in thyroid-associated ophthalmopathy. Arch. Clin. Exp. Ophthalmol. 2002; 240 (7): 515–20.

20. Yatsenko O.Yu., Tyurin I.E. Orbital radiographic anatomy. Part 2. Orbital soft tissue contents. Vestnik Rentgenologii i Radiologii [Russian Journal of Radiology]. 2016; 97 (1):5–13 (in Russ.).


Review

For citations:


Yatsenko O.Yu., Tyurin I.E. X-ray semiotics of endocrine ophthalmopathy. Part 1. Extraocular muscles and orbital cellular tissue. Journal of radiology and nuclear medicine. 2016;97(3):133-142. (In Russ.) https://doi.org/10.20862/0042-4676-2016-97-3-133-142

Views: 3705


ISSN 0042-4676 (Print)
ISSN 2619-0478 (Online)