Preview

Journal of radiology and nuclear medicine

Advanced search

NO-REFLOW PHENOMENON IN THE PRACTICE OF AN ENDOVASCULAR SURGEON

https://doi.org/10.20862/0042-4676-2014-0-1-51-55

Abstract

 

No-reflow phenomenon is a complication of percutaneous coronary intervention and is the absence of distal coronary bed filling. The main cause of this phenomenon is distal embolism of the coronary artery by atheromatous and thrombotic masses. The paper gives different classifications for evaluation of myocardial and coronary reperfusion. The use of aspiration catheters, glycoprotein IIb/IIIa receptor inhibitors and other drugs that affect prognosis in patients with this phenomenon is also touched upon.

 

 


About the Authors

A. M. Gerasimov
Russian Cardiology Research-and-Production Complex, Ministry of Health of the RF, ul. Tret’ya Cherepkovskaya, 15a, Moscow, 121552, Russian Federation
Russian Federation

MD, PhD, Cardiologist



A. S. Tereshchenko
Russian Cardiology Research-and-Production Complex, Ministry of Health of the RF, ul. Tret’ya Cherepkovskaya, 15a, Moscow, 121552, Russian Federation
Russian Federation

Cardiologist



E. V. Merkulov
Russian Cardiology Research-and-Production Complex, Ministry of Health of the RF, ul. Tret’ya Cherepkovskaya, 15a, Moscow, 121552, Russian Federation
Russian Federation

MD, PhD, Researcher of the Department of Endovascular Diagnosis and Treatment



A. N. Samko
Russian Cardiology Research-and-Production Complex, Ministry of Health of the RF, ul. Tret’ya Cherepkovskaya, 15a, Moscow, 121552, Russian Federation
Russian Federation

MD, PhD, DSc, Professor, Head of the Department of Endovascular Diagnosis and Treatment



References

1. Resnic F.S., Wainstein M., Lee M.K.Y. et al. No-reflow is an independent predictor of death and myocardial infarction after percutaneous coronary intervention. Am. Heart J. 2003; 145: 42–6.

2. Gerber B.L., Rochitte C.E., Melin J.A. et al. Microvascular obstruction and left ventricular remodeling early after acute myocardial infarction. Circulation. 2000; 101: 2734–41.

3. Rezkella S.H., Kloner R.A. No-reflow phenomenon. Circulation. 2002; 105: 656–62.

4. Piana R.N., Paik G.Y., Moscucci M. et al. Incidence and treatment of “no-reflow” after percutaneous coronary intervention. Circulation. 1994; 89: 2514–8.

5. Majno G., Ames A. III, Chiang J. et al. No-reflow after cerebral ischemia. Lancet. 1967; 2: 569–70.

6. Kloner R.A., Ganote C.E., Jennings R.B. The “no-reflow” phenomenon after temporary coronary occlusion in the dog. J. Clin. Invest. 1974; 54: 1496–508.

7. Topol E.J., Yadav J.S. Recognition of the importance of embolization in atherosclerotic vascular disease. Circulation. 2000; 101: 570–80.

8. Van’t Hof A.W., Liem A., Suryapranata H. et al. Angiographic assessment of myocardial perfusion in patients treated with primary angioplasty for acute myocardial infarction: myocardial blush grade. Circulation. 1998; 97: 2302–6.

9. Cannon C.P., Sharis P.J., Schweiger M.J. et al. Prospective validation of a composite end point in thrombolytic trials of acute myocardial infarction (TIMI 4 and 5). Thrombosis in Myocardial Infarction. Am. J. Cardiol. 1997; 80: 696–9.

10. Gibson C.M., Murphy S.A., Rizzo M.J. et al. Relationship between TIMI frame count and clinical outcomes after thrombolytic administration. Circulation. 1999; 99: 1945–50.

11. Stone G.W., Peterson M.A., Lansky A.J. et al. Impact of normalized myocar-dial perfusion after successful angioplasty in acute myocardial infarction. J. Am. Coll. Cardiol. 2002; 39: 591–7.

12. De Luca G., van’t Hof A.W., Otter-vanger J.P. et al. Unsuccessful reper-fusion in patients with ST-segment elevation myocardial infarction treated with primary angioplasty. Am. Heart J. 2005; 150: 557–62.

13. Montalescot G., Barragan P., Witten-berg O. et al. Platelet glycoprotein IIb/IIIa inhibition with coronary stenting for acute myocardial infarction. N. Engl. J. Med. 2001; 344: 1895–903.

14. Petronio A.S., Rovai D., Musumeci G. et al. Effects of abciximab on micro-vascular integrity and left ventricular functional recovery in patients with acute infarction treated by primary coronary angioplasty. Eur. Heart J. 2003; 24: 67–76.

15. De Luca G., Suryapranata H., Stone G.W. et al. Abciximab as adjunctive therapy to reperfusion in acute ST-segment elevation myocardial infarction: a meta-analysis of randomized trials. J. Am. Med. Assoc. 2005; 293: 1759–65.

16. De Luca L., Sardella G., Davidson C.J. et al. Impact of intracoronary aspiration thrombectomy uring primary angioplasty on left ventricular remodeling in patients with anterior ST-elevation myocardial infarction. Heart. 2006; 92: 951–7.

17. Ole Fröbert, Bo Lagerqvist, Göran K. Olivecrona et al. Thrombus Aspiration during ST-Segment Elevation Myocardial Infarction. N. Engl. J. Med. 2013. DOI: 10.1056/NEJMoa1308789

18. Vlaar P.J., Svilaas T., van der Horst I.C. et al. Cardiac death and reinfarction after 1 year in the Thrombus Aspiration during Percutaneous coronary intervention in Acute myocardial infarction Study (TAPAS): a 1-year follow-up study. Lancet. 2008; 371, 9628: 1915–20.

19. Mahaffey K.W., Puma J.A., Barbagaleta N.A. et al. Adenosine as an adjunct to thrombolytic therapy for acute myocardial infarction: results of a multicenter, randomized, placebo-controlled trial: the Acute Myocardial Infarction STudy of ADenosine (AMISTAD) trial. J. Am. Coll. Car-diol. 1999; 34: 1711–20.

20. Ross A.M., Gibbons R.J., Stone G.W. et al. A randomized double-blinded, placebo-controlled multicenter trial of adenosine as an adjunct to reperfusion in the treatment of acute myocardial infarction (AMISTAD-II). J. Am. Coll. Cardiol. 2005; 45: 1775–80.

21. Ishii H., Ichimiya S., Kanashiro et al. Impact of a single intravenous administration of nicorandil before reperfusion in patients with ST-segment elevation myocardial infarction. Circulation. 2005; 112: 1284–8.


Review

For citations:


Gerasimov A.M., Tereshchenko A.S., Merkulov E.V., Samko A.N. NO-REFLOW PHENOMENON IN THE PRACTICE OF AN ENDOVASCULAR SURGEON. Journal of radiology and nuclear medicine. 2014;(1):51-55. (In Russ.) https://doi.org/10.20862/0042-4676-2014-0-1-51-55

Views: 8235


ISSN 0042-4676 (Print)
ISSN 2619-0478 (Online)