Topical Issues of Rational Use of Iodine-Containing Contrast Agents in X-Ray Diagnostics
https://doi.org/10.20862/0042-4676-2021-102-4-255-262
Abstract
The possibilities of rational use of iodine radiopaque agents in computed tomography and percutaneous coronary interventions are considered, taking into account the route, method of their administration and the viscosity of their solutions. When fixing the rate of iodine administration and the temperature of the injected solution, the required injection pressure of the contrast media is determined by the solution viscosity.
About the Author
N. L. Shimanovskiy
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Nikolay L. Shimanovskiy, Dr. Med. Sc., Professor, Corresponding Member of RAS, Chief of Chair of Molecular Pharmacology and Radiobiology
ul. Ostrovityanova, 1, Moscow, 117997
References
1. Schöckel L, Jost G, Seidensticker P, et al. Developments in X-Ray contrast media and the potential impact on computed tomography. Invest Radiol. 2020; 55(9): 592–7. https://doi.org/10.1097/RLI.0000000000000696.
2. Ojeda S, Romaguera R, Cruz-González I, Moreno R. Spanish Cardiac Catheterization and Coronary Intervention Registry. 29th Official Report of the Interventional Cardiology Association of the Spanish Society of Cardiology (1990–2019). Rev Esp Cardiol (Engl Ed). 2020; 73(11): 927–36. https://doi.org/10.1016/j.rec.2020.09.005.
3. ESUR Guidelines on contrast agents. European Society of Urogenital Radiology. Available at: http://www.esur.org/fileadmin/content/2019/ESUR_ Guidelines_10.0_Final_Version.pdf (accessed June 17, 2021).
4. Suh YJ, Yoon SH, Hong H, et al. Acute adverse reactions to nonionic iodinated contrast media: a meta-analysis. Invest Radiol. 2019; 54(9): 589–99. https://doi.org/10.1097/RLI.0000000000000568.
5. Чучалин А.Г., Яснецов В.В. (ред.) Федеральное руководство по использованию лекарственных средств (формулярная система). Вып. 17. М.; 2016: 942–6. [Chuchalin АG, Yasnetsov VV (Eds) Federal guidelines for the use of drugs (formulary system). Issue 17. Мoscow; 2016: 942–6 (in Russ.).]
6. Palkowitsch PK, Bostelmann S, Lengsfeld P. Safety and tolerability of iopromide intravascular use: a pooled analysis of three non-interventional studies in 132,012 patients. Acta Radiol. 2014; 55(6): 707–14. https://doi.org/10.1177/0284185113504753.
7. Chen JY, Liu Y, Zhou YL, et al. Safety and tolerability of iopromide in patients undergoing cardiac catheterization: realworld multicenter experience with 17,513 patients from the TRUST trial. Int J Cardiovasc Imaging. 2015; 31(7): 1281–91. https://doi.org/10.1007/s10554-015-0688-9.
8. Rengo M, Dharampal A, Lubbers M, et al. Impact of iodine concentration and iodine delivery rate on contrast enhancement in coronary CT angiography: a randomized multicenter trial (CT-CON). Eur Radiol. 2019; 29(11): 6109–18. https://doi.org/10.1007/s00330-019-06196-7.
9. García M, Aguirre U, Martinez A, et al. Acute adverse reactions to iopromide vs iomeprol: a retrospective analysis of spontaneous reporting from a radiology department. Br J Radiol. 2014; 87(1033): 20130511. https://doi.org/10.1259/bjr.20130511.
10. Kok M, Mihl C, Hendriks BM, et al. Patient comfort during contrast media injection in coronary computed tomographic angiography using varying contrast media concentrations and flow rates: results from the EICAR Trial. Invest Radiol. 2016; 51(12): 810–15. https://doi.org/10.1097/RLI.0000000000000284.
11. Halsell RD. Heating contrast media: role in contemporary angiography. Radiology. 1987; 164: 276–8. https://doi.org/10.1148/radiology.164.1.3588919.
12. Chaya A, Jost G, Endrikat J. Piston-based vs peristaltic pumpbased ct injector systems. Radiol Technol. 2019; 90(4): 344–52.
13. Wildberger JE, Mahnken AH, Seidensticker PR. Aorto-peripheral MDCT angiography: implications for contrast medium delivery. Imaging Decisions. 2007; 4: 8–12. https://doi.org/10.1111/j.1617-0830.2007.00109.x.
14. ACR Manual on Contrast Media 2021. ACR Committee on Drugs and Contrast Media. Available at: https://www.acr.org/-/media/ACR/files/clinical-resources/ contrast_media.pdf (accessed June 17, 2021).
15. Hendriks BM, Kok M, Mihl C, et al. Individually tailored contrast enhancement in CT pulmonary angiography. Br J Radiol. 2016; 89: 20150850. https://doi.org/10.1259/bjr.20150850.
16. Endrikat J, Michel A, Kölbach R, et al. Risk of hypersensitivity reactions to iopromide after intra-arterial versus intravenous administration: a nested case-control analysis of 133,331 patients. Invest Radiol. 2020; 55(1): 38–44. https://doi.org/10.1097/RLI.0000000000000611.
17. Cha MJ, Kang DY, Lee W, et al. Hypersensitivity reactions to iodinated contrast media: a multicenter study of 196 081 patients. Radiology. 2019; 293(1): 117–24. https://doi.org/10.1148/radiol.2019190485.
18. Zhang B, Liu J, Dong Y, et al. Extrinsic warming of lowosmolality iodinated contrast media to 37 °C reduced the rate of allergic-like reaction. Allergy Asthma Proc. 2018; 39(6): e55–63. https://doi.org/10.2500/aap.2018.39.4160.
19. Sodagari F, Mozaffary A, Wood CG 3rd, et al. Reactions to both nonionic iodinated and gadolinium-based contrast media: incidence and clinical characteristics. AJR Am J Roentgenol. 2018; 210(4): 715–9. https://doi.org/10.2214/AJR.17.18655.
20. Kim SR, Lee JH, Park KH, et al. Varied incidence of immediate adverse reactions to low-osmolar non-ionic iodide radiocontrast media used in computed tomography. Clin Exp Allergy. 2017; 47(1): 106–12. https://doi.org/10.1111/cea.12803.
21. Dillman JR, Strouse PJ, Ellis JH, et al. Incidence and severity of acute allergic-like reactions to i.v. nonionic iodinated contrast material in children. AJR Am J Roentgenol. 2007; 188(6): 1643–7. https://doi.org/10.2214/AJR.06.1328.
22. Kopp AF, Mortele KJ, Cho YD, et al. Prevalence of acute reactions to iopromide: postmarketing surveillance study of 74,717 patients. Acta Radiol. 2008; 49(8): 902–11. https://doi.org/10.1080/02841850802282811.
23. Schild H. CM, to see or not to see. Schering Diagnositics, Bayer. 1994. Last update 2018. Available at: https://www.librarything.com/work/10548853 (accessed June 17, 2021).
24. Guéant-Rodriguez RM, Romano A, Barbaud A, et al. Hypersensitivity reactions to iodinated contrast media. Curr Pharm Des. 2006; 12(26): 3359–72. https://doi.org/10.2174/138161206778193999.
25. From AM, Al Badarin FJ, McDonald FS, et al. Iodixanol versus low-osmolar contrast media for prevention of contrast induced nephropathy: meta-analysis of randomized, controlled trials. Circ Cardiovasc Interv. 2010; 3(4): 351–8. https://doi.org/10.1161/CIRCINTERVENTIONS.109.917070.
26. Nijssen EC, Rennenberg RJ, Nelemans PJ, et al. Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrastinduced nephropathy (AMACING): a prospective, randomised, phase 3, controlled, open-label, non-inferiority trial. Lancet. 2017; 389(10076): 1312–22. https://doi.org/10.1016/S0140-6736(17)30057-0.
27. Nijssen EC, Nelemans PJ, Rennenberg RJ, et al. prophylactic intravenous hydration to protect renal function from intravascular iodinated contrast material (AMACING): longterm results of a prospective, randomised, controlled trial. EClinicalMedicine. 2018; 4–5: 109–16. https://doi.org/10.1016/j.eclinm.2018.10.007.
Review
For citations:
Shimanovskiy N.L. Topical Issues of Rational Use of Iodine-Containing Contrast Agents in X-Ray Diagnostics. Journal of radiology and nuclear medicine. 2021;102(4):255-262. (In Russ.) https://doi.org/10.20862/0042-4676-2021-102-4-255-262
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