<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rentrad</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник рентгенологии и радиологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of radiology and nuclear medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4676</issn><issn pub-type="epub">2619-0478</issn><publisher><publisher-name>Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20862/0042-4676-2015-0-6-43-55</article-id><article-id custom-type="elpub" pub-id-type="custom">rentrad-92</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS OF LITERATURE</subject></subj-group></article-categories><title-group><article-title>Мультипараметрическая магнитно-резонансная томография в диагностике рака шейки матки</article-title><trans-title-group xml:lang="en"><trans-title>Multiparameter magnetic resonance imaging in the diagnosis of cancer of the cervix uteri</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарачкова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarachkova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант</p></bio><bio xml:lang="en"><p>Postgraduate</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стрельцова</surname><given-names>О. Н,</given-names></name><name name-style="western" xml:lang="en"><surname>Strel’tsova</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к. м. н., рентгенолог</p></bio><bio xml:lang="en"><p>MD, PhD, Radiologist</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панов</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Panov</surname><given-names>V. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к. м. н., доцент кафедры лучевой диагностики, лучевой терапии и медицинской физики, вед. науч. сотр.</p></bio><bio xml:lang="en"><p>MD, PhD, Associate Professor of the Department of Radiation Diagnosis,Radiotherapy and Medical Physics, Leading Research Associate</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Базаева</surname><given-names>И. Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Bazaeva</surname><given-names>I. Ya.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант</p></bio><bio xml:lang="en"><p>Postgraduate</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тюрин</surname><given-names>И. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Tyurin</surname><given-names>I. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., профессор, заведующий кафедрой лучевой диагностики, лучевой терапии и медицинской физики, вед. науч. сотр.</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, Professor, Head of the Department of Radiation Diagnosis,Radiotherapy and Medical Physics, Leading Research Associate</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ДПО «Российская медицинская академия последипломного образования» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Postgraduate Education, Ministry of Health of the RF</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «Российский онкологический научный центр им. Н.Н. Блохина» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.N. Blokhin Russian Cancer Research Center, Ministry of Health of the RF</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБОУ ДПО «Российская медицинская академия последипломного образования» Министерства здравоохранения РФ,  ФГБУ «Российский онкологический научный центр им. Н.Н. Блохина» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Postgraduate Education, Ministry of Health of the RF, N.N. Blokhin Russian Cancer Research Center, Ministry of Health of the RF</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>09</day><month>03</month><year>2016</year></pub-date><volume>0</volume><issue>6</issue><fpage>43</fpage><lpage>55</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тарачкова Е.В., Стрельцова О.Н., Панов О.В., Базаева И.Я., Тюрин И.Е., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Тарачкова Е.В., Стрельцова О.Н., Панов О.В., Базаева И.Я., Тюрин И.Е.</copyright-holder><copyright-holder xml:lang="en">Tarachkova E.V., Strel’tsova O.N., Panov V.O., Bazaeva I.Y., Tyurin I.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.russianradiology.ru/jour/article/view/92">https://www.russianradiology.ru/jour/article/view/92</self-uri><abstract><p>Рак шейки матки (РШМ) занимает третье место в структуре заболеваемости злокачественными новообразованиями у женщин. Выбор метода лечения РШМ прежде всего зависит от распространенности опухолевого процесса, то есть от стадии заболевания. Определение стадии РШМ основано на клинической классификации Международной федерации акушеров-гинекологов FIGO (2009 г.) и имеет ряд существенных ограничений в оценке инвазии параметриев, распространенияопухоли на стенки таза, поражения регионарных лимфоузлов и определении истинных размеров опухоли. В настоящее время методом выбора при проведении стадирования инвазивного РШМ является магнитно-резонансная томография (МРТ). Мультипараметрическая МРТ позволяет повысить эффективность диагностики, в том числе микроинвазивного рака шейки матки (FIGO, 2009 г.), планировать хирургическое и/или химиолучевое лечение, оценивать его эффективность, диагностировать местный рецидив заболевания.</p></abstract><trans-abstract xml:lang="en"><p>Cancer of the cervix uteri (CCU) ranks third in the incidence of malignancies in women. The choice of CCU treatment mainly depends on the extent of the tumor process, i.e. the stage of the disease. Determining the stage of CCU is based on the clinical classification of the International Federation of Gynecology and Obstetrics (FIGO) (2009) and has a number of substantial limitations in evaluating parametrial invasion, tumor spread to the pelvic wall, and involvement of regional lymph nodes and in determining the true tumor sizes. Magnetic resonance imaging (MRI) is now the method of choice in staging invasive CCU.Multiparameter MRI will be able to enhance the efficiency of diagnosing microinvasive CCU as well (FIGO 2009), to plan surgical and/or chemoradiation treatment, to evaluate its efficiency, and to diagnose locally recurrent CCU.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак шейки матки</kwd><kwd>Международная федерация акушеров- гинекологов</kwd><kwd>магнитно-резонансная томография</kwd><kwd>диффузионно-взвешенные изображения</kwd><kwd>измеряемый коэффициент диффузии</kwd><kwd>динамическая магнитно-резонансная томография с контрастным усилением</kwd><kwd>позитронная эмиссионная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cancer of the cervix uteri</kwd><kwd>International Federation of Gynecology and Obstetrics</kwd><kwd>magnetic resonance imaging</kwd><kwd>diffusion-weighted magnetic resonance images</kwd><kwd>measured diffusion coefficient</kwd><kwd>dynamic contrast-enhanced magnetic resonance imaging</kwd><kwd>positron emission tomography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Chissov V.I., Starinskiy V.V., Petrova G.V. Status of cancer care in Russia in 2010. Moscow; 2011 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Chissov V.I., Starinskiy V.V., Petrova G.V. Status of cancer care in Russia in 2010. Moscow; 2011 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Siegel R., Naishadham D., Jemal A. Cancer statistics, 2013. CA Cancer J. Clin. 2013; 63 (1): 11–30.</mixed-citation><mixed-citation xml:lang="en">Siegel R., Naishadham D., Jemal A. Cancer statistics, 2013. CA Cancer J. Clin. 2013; 63 (1): 11–30.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Axel’ E.M. Statistic of malignance gynecologic tumors. Onkoginekologiya. 2012 (1): 18–23 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Axel’ E.M. Statistic of malignance gynecologic tumors. Onkoginekologiya. 2012 (1): 18–23 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Trufanov V.G., Panov V.O. Handbook of radiation diagnostic in gynecology. St. Petersburg: ELBI-SPb; 2008: 590–2, 616 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Trufanov V.G., Panov V.O. Handbook of radiation diagnostic in gynecology. St. Petersburg: ELBI-SPb; 2008: 590–2, 616 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Davydov M.I., Kuznetsov V.V., Nechushkina M.V. Lections of oncogynecology. Moscow: MEDpressinform; 2009: 20–1, 33 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Davydov M.I., Kuznetsov V.V., Nechushkina M.V. Lections of oncogynecology. Moscow: MEDpressinform; 2009: 20–1, 33 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Paliychuk O.V., Polishchuk L.Z. The role of infection in etiology and pathogenesis of cervical intraepithelial neoplasms and cervical cancer. Reproduktivnoe zdorov’e zhenshchiny. 2007; 32 (3): 10–6 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Paliychuk O.V., Polishchuk L.Z. The role of infection in etiology and pathogenesis of cervical intraepithelial neoplasms and cervical cancer. Reproduktivnoe zdorov’e zhenshchiny. 2007; 32 (3): 10–6 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Polonskaya N.Yu., Yurasova I.V., Sokol’skaya T.Yu. Benefits and efficacy of standardization of cythology methods in gynecology. Klinicheskaya laboratornaya diagnostika. 2004; 1 (11): 47–50 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Polonskaya N.Yu., Yurasova I.V., Sokol’skaya T.Yu. Benefits and efficacy of standardization of cythology methods in gynecology. Klinicheskaya laboratornaya diagnostika. 2004; 1 (11): 47–50 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Hopman A.H., Smedts F., Dignef W., Ummelen M., Sonke G., Mravunac M., Vooijs G.P., Speel E.J., Ramaekers F.C. Transition of highgrade cervical intraepithelial neoplasia to micro-invasive carcinoma is characterized by integration of HPV 16/18 and numerical chromosome abnormalities. J. Pathol. 2004; 202 (1): 23–33.</mixed-citation><mixed-citation xml:lang="en">Hopman A.H., Smedts F., Dignef W., Ummelen M., Sonke G., Mravunac M., Vooijs G.P., Speel E.J., Ramaekers F.C. Transition of highgrade cervical intraepithelial neoplasia to micro-invasive carcinoma is characterized by integration of HPV 16/18 and numerical chromosome abnormalities. J. Pathol. 2004; 202 (1): 23–33.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Petsuksiri J., Jaishuen A., Pattaranutaporn P., Chansilpa Y. Advanced imaging applications for locally advanced cervical cancer. Asian Pacific. J. Cancer Prevention. 2012; 13 (5): 1713–8.</mixed-citation><mixed-citation xml:lang="en">Petsuksiri J., Jaishuen A., Pattaranutaporn P., Chansilpa Y. Advanced imaging applications for locally advanced cervical cancer. Asian Pacific. J. Cancer Prevention. 2012; 13 (5): 1713–8.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Makarov I.O., Ovsyannikova T.V., Shemanaeva T.V., Borovkova E.I., Kulikov I.A., Guriev T.D. 3D US in normal and abnormal cervix. Akusherstvo, ginekologiya i reproduktsiya. 2013; 7 (2): 23–6 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Makarov I.O., Ovsyannikova T.V., Shemanaeva T.V., Borovkova E.I., Kulikov I.A., Guriev T.D. 3D US in normal and abnormal cervix. Akusherstvo, ginekologiya i reproduktsiya. 2013; 7 (2): 23–6 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Adamyan L.V., Demidov V.N., Gus A.I., Obel’chak I.S. Handbook of radiation diagnostic and therapy in obstetrics and gynecology. Moscow: GEOTAR-Media; 2012 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Adamyan L.V., Demidov V.N., Gus A.I., Obel’chak I.S. Handbook of radiation diagnostic and therapy in obstetrics and gynecology. Moscow: GEOTAR-Media; 2012 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Rogozhin V.I. MRT in gynecologic practice. Russian eltctronic journal of radiology. 2012; 2 (3): 27–40 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Rogozhin V.I. MRT in gynecologic practice. Russian eltctronic journal of radiology. 2012; 2 (3): 27–40 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Pecorelli S. Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. Int. J. Gynaecol. Obstet. 2009; 105 (2): 103–4.</mixed-citation><mixed-citation xml:lang="en">Pecorelli S. Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. Int. J. Gynaecol. Obstet. 2009; 105 (2): 103–4.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Liyanage S.H., Roberts C.A., Rockall A.G. MRI and PET scans for primary staging and detection of cervical cancer recurrence. Womens Health (Lond Engl). 2010; 6 (2): 251–69.</mixed-citation><mixed-citation xml:lang="en">Liyanage S.H., Roberts C.A., Rockall A.G. MRI and PET scans for primary staging and detection of cervical cancer recurrence. Womens Health (Lond Engl). 2010; 6 (2): 251–69.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Kim H.S., Kim C.K., Park B.K., Huh S.J., Kim B. Evaluation of therapeutic response to concurrent chemoradiotherapy in patients with cervical cancer using diffusionweighted MR imaging. J. Magn. Reson. Imaging. 2013; 37 (1): 187–93.</mixed-citation><mixed-citation xml:lang="en">Kim H.S., Kim C.K., Park B.K., Huh S.J., Kim B. Evaluation of therapeutic response to concurrent chemoradiotherapy in patients with cervical cancer using diffusionweighted MR imaging. J. Magn. Reson. Imaging. 2013; 37 (1): 187–93.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Freeman S.J., Aly A.M., Kataoka M.Y., Addley H.C., Reinhold C., Sala E. The revised FIGO staging system for uterine malignancies: implications for MR imaging. Radiographics. 2012; 32 (6): 1805–27.</mixed-citation><mixed-citation xml:lang="en">Freeman S.J., Aly A.M., Kataoka M.Y., Addley H.C., Reinhold C., Sala E. The revised FIGO staging system for uterine malignancies: implications for MR imaging. Radiographics. 2012; 32 (6): 1805–27.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Kraljevic Z., Viskovic K., Ledinsky M., Zadravec D., Grbavac I., Bilandzija M. et al. Primary uterine cervical cancer: correlation of preoperative magnetic resonance imaging and clinical staging (FIGO) with histopathology findings. Coll. Antropol. 2013; 37 (2): 561–8.</mixed-citation><mixed-citation xml:lang="en">Kraljevic Z., Viskovic K., Ledinsky M., Zadravec D., Grbavac I., Bilandzija M. et al. Primary uterine cervical cancer: correlation of preoperative magnetic resonance imaging and clinical staging (FIGO) with histopathology findings. Coll. Antropol. 2013; 37 (2): 561–8.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Dhoot N.M., Kumar V., Shinagare A., Kataki A.C., Barmon D., Bhuyan U. Evaluation of carcinoma cervix using magnetic resonance imaging: correlation with clinical FIGO staging and impact on management. J. Med. Imaging Radiat. Oncol. 2012; 56 (1): 58–65.</mixed-citation><mixed-citation xml:lang="en">Dhoot N.M., Kumar V., Shinagare A., Kataki A.C., Barmon D., Bhuyan U. Evaluation of carcinoma cervix using magnetic resonance imaging: correlation with clinical FIGO staging and impact on management. J. Med. Imaging Radiat. Oncol. 2012; 56 (1): 58–65.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Hricak H., Lacey C.G., Sandles L.G., Chang Y.C., Winkler M.L., Stern J.L. Invasive cervical carcinoma: comparison of MR imaging and surgical findings. Radiology. 1988; 166 (3): 623–31.</mixed-citation><mixed-citation xml:lang="en">Hricak H., Lacey C.G., Sandles L.G., Chang Y.C., Winkler M.L., Stern J.L. Invasive cervical carcinoma: comparison of MR imaging and surgical findings. Radiology. 1988; 166 (3): 623–31.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Lam W.W., So N.M., Yang W.T., Metreweli C. Detection of parametrial invasion in cervical carcinoma: role of short tau inversion recovery sequence. Clin. Radiol. 2000; 55 (9): 702–7.</mixed-citation><mixed-citation xml:lang="en">Lam W.W., So N.M., Yang W.T., Metreweli C. Detection of parametrial invasion in cervical carcinoma: role of short tau inversion recovery sequence. Clin. Radiol. 2000; 55 (9): 702–7.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Chung H.H., Kang S.B., Cho J.Y., Kim J.W., Park N.H., Song Y.S. et al. Can preoperative MRI accurately evaluate nodal and parametrial invasion in early stage cervical cancer? Jpn J. Clin. Oncol. 2007; 37 (5): 370–5.</mixed-citation><mixed-citation xml:lang="en">Chung H.H., Kang S.B., Cho J.Y., Kim J.W., Park N.H., Song Y.S. et al. Can preoperative MRI accurately evaluate nodal and parametrial invasion in early stage cervical cancer? Jpn J. Clin. Oncol. 2007; 37 (5): 370–5.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Iwata S., Joja I., Okuno K., Miyagi Y., Sakaguchi Y., Kudo T., Hiraki Y. Cervical carcinoma with full-thickness stromal invasion: efficacy of dynamic MR imaging in the assessment of parametrial involvement. Radiat. Med. 2002; 20 (5): 247–55.</mixed-citation><mixed-citation xml:lang="en">Iwata S., Joja I., Okuno K., Miyagi Y., Sakaguchi Y., Kudo T., Hiraki Y. Cervical carcinoma with full-thickness stromal invasion: efficacy of dynamic MR imaging in the assessment of parametrial involvement. Radiat. Med. 2002; 20 (5): 247–55.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Shiraiwa M., Joja I., Asakawa T., Okuno K., Shibutani O., Akamatsu N. et al. Cervical carcinoma: efficacy of thin-section oblique axial T2- weighted images for evaluating parametrial invasion. Abdom. Imaging. 1999; 24 (5): 514–9.</mixed-citation><mixed-citation xml:lang="en">Shiraiwa M., Joja I., Asakawa T., Okuno K., Shibutani O., Akamatsu N. et al. Cervical carcinoma: efficacy of thin-section oblique axial T2- weighted images for evaluating parametrial invasion. Abdom. Imaging. 1999; 24 (5): 514–9.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Hawighorst H., Knapstein P.G., Weikel W., Knopp M.V., Schaeffer U., Brix G. et al. Cervical carcinoma: comparison of standard and pharmacokinetic MR imaging. Radiology. 1996; 201 (2): 531–9.</mixed-citation><mixed-citation xml:lang="en">Hawighorst H., Knapstein P.G., Weikel W., Knopp M.V., Schaeffer U., Brix G. et al. Cervical carcinoma: comparison of standard and pharmacokinetic MR imaging. Radiology. 1996; 201 (2): 531–9.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Rauch G.M., Kaur H., Choi H ,Ernst R.D., Klopp A.H., Boonsirikamchai P. et al. Optimization of MR imaging for pretreatment evaluation of patients with endometrial and cervical cancer. Radiographics. 2014; 34 (4): 1082–98.</mixed-citation><mixed-citation xml:lang="en">Rauch G.M., Kaur H., Choi H ,Ernst R.D., Klopp A.H., Boonsirikamchai P. et al. Optimization of MR imaging for pretreatment evaluation of patients with endometrial and cervical cancer. Radiographics. 2014; 34 (4): 1082–98.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Sala E., Rockall A.G., Freeman S.J., Mitchell D.G., Reinhold C. The added role of MR imaging in treatment stratification of patients with gynecologic malignancies: what the radiologist needs to know. Radiology. 2013; 266 (3): 717–40.</mixed-citation><mixed-citation xml:lang="en">Sala E., Rockall A.G., Freeman S.J., Mitchell D.G., Reinhold C. The added role of MR imaging in treatment stratification of patients with gynecologic malignancies: what the radiologist needs to know. Radiology. 2013; 266 (3): 717–40.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Balleyguier C., Sala E., Da Cunha T., Bergman A., Brkljacic B., Danza F. et al. Staging of uterine cervical cancer with MRI: guidelines of the European Society of Urogenital Radiology. Eur. Radiol. 2011; 21 (5): 1102–10.</mixed-citation><mixed-citation xml:lang="en">Balleyguier C., Sala E., Da Cunha T., Bergman A., Brkljacic B., Danza F. et al. Staging of uterine cervical cancer with MRI: guidelines of the European Society of Urogenital Radiology. Eur. Radiol. 2011; 21 (5): 1102–10.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Lichy M.P., Wietek B.M., Mugler J.P., 3rd, Horger W., Menzel M.I., Anastasiadis A. et al. Magnetic resonance imaging of the body trunk using a single-slab, 3-dimensional, T2-weighted turbo-spin-echo sequence with high sampling efficiency (SPACE) for high spatial resolution imaging: initial clinical experiences. Invest. Radiol. 2005; 40 (12): 754–60.</mixed-citation><mixed-citation xml:lang="en">Lichy M.P., Wietek B.M., Mugler J.P., 3rd, Horger W., Menzel M.I., Anastasiadis A. et al. Magnetic resonance imaging of the body trunk using a single-slab, 3-dimensional, T2-weighted turbo-spin-echo sequence with high sampling efficiency (SPACE) for high spatial resolution imaging: initial clinical experiences. Invest. Radiol. 2005; 40 (12): 754–60.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Proscia N., Jaffe T.A., Neville A.M., Wang C.L., Dale B.M., Merkle E.M. MRI of the pelvis in women: 3D versus 2D T2-weighted technique. Am. J. Roentgenol. 2010; 195 (1): 254–9.</mixed-citation><mixed-citation xml:lang="en">Proscia N., Jaffe T.A., Neville A.M., Wang C.L., Dale B.M., Merkle E.M. MRI of the pelvis in women: 3D versus 2D T2-weighted technique. Am. J. Roentgenol. 2010; 195 (1): 254–9.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Bhosale P., Peungjesada S., Devine C., Balachandran A., Iyer R. Role of magnetic resonance imaging as an adjunct to clinical staging in cervical carcinoma. J. Comput. Assist. Tomogr. 2010; 34 (6): 855–64. 31. Wootton J.H., Hsu I.C., Diederich C.J. Endocervical ultrasound applicator for integrated hyperthermia and HDR brachytherapy in the treatment of locally advanced cervical carcinoma. Med. Phys. 2011; 38 (2): 598–611.</mixed-citation><mixed-citation xml:lang="en">Bhosale P., Peungjesada S., Devine C., Balachandran A., Iyer R. Role of magnetic resonance imaging as an adjunct to clinical staging in cervical carcinoma. J. Comput. Assist. Tomogr. 2010; 34 (6): 855–64. 31. Wootton J.H., Hsu I.C., Diederich C.J. Endocervical ultrasound applicator for integrated hyperthermia and HDR brachytherapy in the treatment of locally advanced cervical carcinoma. Med. Phys. 2011; 38 (2): 598–611.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Aksenova S.V., Nudnov N.V., Kreynina Yu.M. Magnetic-resonance tomography as a method of diagnostic and monitoring oncogynecologic patients with vagina tumors. In: Congress RAR 2014. Moscow: Chelovek i ego zdorov’e; 2014: 70–1 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Aksenova S.V., Nudnov N.V., Kreynina Yu.M. Magnetic-resonance tomography as a method of diagnostic and monitoring oncogynecologic patients with vagina tumors. In: Congress RAR 2014. Moscow: Chelovek i ego zdorov’e; 2014: 70–1 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Payne G.S., Schmidt M., Morgan V.A., Giles S., Bridges J., Ind T., DeSouza N.M. Evaluation of magnetic resonance diffusion and spectroscopy measurements as predictive biomarkers in stage 1 cervical cancer. Gynecol. Oncol. 2010; 116 (2): 246–52.</mixed-citation><mixed-citation xml:lang="en">Payne G.S., Schmidt M., Morgan V.A., Giles S., Bridges J., Ind T., DeSouza N.M. Evaluation of magnetic resonance diffusion and spectroscopy measurements as predictive biomarkers in stage 1 cervical cancer. Gynecol. Oncol. 2010; 116 (2): 246–52.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Chen J., Zhang Y., Liang B., Yang Z. The utility of diffusion-weighted MR imaging in cervical cancer. Eur. J. Radiol. 2010; 74 (3): e101–6.</mixed-citation><mixed-citation xml:lang="en">Chen J., Zhang Y., Liang B., Yang Z. The utility of diffusion-weighted MR imaging in cervical cancer. Eur. J. Radiol. 2010; 74 (3): e101–6.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Levy A., Medjhoul A., Caramella C., Zareski E., Berges O., Chargari C. et al. Interest of diffusion-weighted echo-planar MR imaging and apparent diffusion coefficient mapping in gynecological malignancies: a review. J. Magn. Reson. Imaging. 2011; 33 (5): 1020–7.</mixed-citation><mixed-citation xml:lang="en">Levy A., Medjhoul A., Caramella C., Zareski E., Berges O., Chargari C. et al. Interest of diffusion-weighted echo-planar MR imaging and apparent diffusion coefficient mapping in gynecological malignancies: a review. J. Magn. Reson. Imaging. 2011; 33 (5): 1020–7.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Harry V.N., Semple S.I., Parkin D.E., Gilbert F.J. Use of new imaging techniques to predict tumour response to therapy. Lancet. Oncol. 2010; 11 (1): 92–102.</mixed-citation><mixed-citation xml:lang="en">Harry V.N., Semple S.I., Parkin D.E., Gilbert F.J. Use of new imaging techniques to predict tumour response to therapy. Lancet. Oncol. 2010; 11 (1): 92–102.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Thoeny H.C., Ross B.D. Predicting and monitoring cancer treatment response with diffusion-weighted MRI. J. Magn. Reson. Imaging. 2010; 32 (1): 2–16.</mixed-citation><mixed-citation xml:lang="en">Thoeny H.C., Ross B.D. Predicting and monitoring cancer treatment response with diffusion-weighted MRI. J. Magn. Reson. Imaging. 2010; 32 (1): 2–16.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Koh D.M., Collins D.J. Diffusionweighted MRI in the body: applications and challenges in oncology. Am. J. Roentgenol. 2007; 188 (6): 1622–35.</mixed-citation><mixed-citation xml:lang="en">Koh D.M., Collins D.J. Diffusionweighted MRI in the body: applications and challenges in oncology. Am. J. Roentgenol. 2007; 188 (6): 1622–35.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Somoye G., Harry V., Semple S., Plataniotis G., Scott N., Gilbert F.J., Parkin D. Early diffusion weighted magnetic resonance imaging can predict survival in women with locally advanced cancer of the cervix treated with combined chemo-radiation. Eur. Radiol. 2012; 22 (11): 2319–27.</mixed-citation><mixed-citation xml:lang="en">Somoye G., Harry V., Semple S., Plataniotis G., Scott N., Gilbert F.J., Parkin D. Early diffusion weighted magnetic resonance imaging can predict survival in women with locally advanced cancer of the cervix treated with combined chemo-radiation. Eur. Radiol. 2012; 22 (11): 2319–27.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang Y., Chen J.Y., Xie C.M., Mo Y.X., Liu X.W., Liu Y., Wu P.H. Diffusion-weighted magnetic resonance imaging for prediction of response of advanced cervical cancer to chemoradiation. J. Comput. Assist. Tomogr. 2011; 35 (1): 102–7.</mixed-citation><mixed-citation xml:lang="en">Zhang Y., Chen J.Y., Xie C.M., Mo Y.X., Liu X.W., Liu Y., Wu P.H. Diffusion-weighted magnetic resonance imaging for prediction of response of advanced cervical cancer to chemoradiation. J. Comput. Assist. Tomogr. 2011; 35 (1): 102–7.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Nakamura K., Joja I., Nagasaka T , Fukushima C., Kusumoto T., Seki N. et al. The mean apparent diffusion coefficient value (ADCmean) on primary cervical cancer is a predictive marker for disease recurrence. Gynecol. Oncol. 2012; 127 (3): 478–83.</mixed-citation><mixed-citation xml:lang="en">Nakamura K., Joja I., Nagasaka T , Fukushima C., Kusumoto T., Seki N. et al. The mean apparent diffusion coefficient value (ADCmean) on primary cervical cancer is a predictive marker for disease recurrence. Gynecol. Oncol. 2012; 127 (3): 478–83.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Noel P., Dube M., Plante M., St-Laurent G. Early cervical carcinoma and fertility-sparing treatment options: MR imaging as a tool in patient selection and a follow-up modality. Radiographics. 2014; 34 (4): 1099–119.</mixed-citation><mixed-citation xml:lang="en">Noel P., Dube M., Plante M., St-Laurent G. Early cervical carcinoma and fertility-sparing treatment options: MR imaging as a tool in patient selection and a follow-up modality. Radiographics. 2014; 34 (4): 1099–119.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Hricak H.S., Swift P.S., Campos Z., Quivey J.M., Gildengorin V., Goranson H. Irradiation of the cervix uteri: value of unenhanced and contrastenhanced MR imaging. Radiology. 1993; 2 (189): 381–8.</mixed-citation><mixed-citation xml:lang="en">Hricak H.S., Swift P.S., Campos Z., Quivey J.M., Gildengorin V., Goranson H. Irradiation of the cervix uteri: value of unenhanced and contrastenhanced MR imaging. Radiology. 1993; 2 (189): 381–8.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">He H., Bhosale P., Wei W., Ramalingam P., Iyer R. MRI is highly specific in determining primary cervical versus endometrial cancer when biopsy results are inconclusive. Clin. Radiol. 2013; 68 (11): 1107–13.</mixed-citation><mixed-citation xml:lang="en">He H., Bhosale P., Wei W., Ramalingam P., Iyer R. MRI is highly specific in determining primary cervical versus endometrial cancer when biopsy results are inconclusive. Clin. Radiol. 2013; 68 (11): 1107–13.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Ellingsen C., Hompland T., Galappathi K., Mathiesen B., Rofstad E.K. DCE-MRI of the hypoxic fraction, radioresponsiveness, and metastatic propensity of cervical carcinoma xenografts. Radiother. Oncol. 2014; 110 (2): 335–41.</mixed-citation><mixed-citation xml:lang="en">Ellingsen C., Hompland T., Galappathi K., Mathiesen B., Rofstad E.K. DCE-MRI of the hypoxic fraction, radioresponsiveness, and metastatic propensity of cervical carcinoma xenografts. Radiother. Oncol. 2014; 110 (2): 335–41.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Andersen E.K., Hole K.H., Lund K.V., Sundfor K., Kristensen G.B., Lyng H., Malinen E. Pharmacokinetic parameters derived from dynamic contrast enhanced MRI of cervical cancers predict chemoradiotherapy outcome. Radiother. Oncol. 2013; 107 (1): 117–22.</mixed-citation><mixed-citation xml:lang="en">Andersen E.K., Hole K.H., Lund K.V., Sundfor K., Kristensen G.B., Lyng H., Malinen E. Pharmacokinetic parameters derived from dynamic contrast enhanced MRI of cervical cancers predict chemoradiotherapy outcome. Radiother. Oncol. 2013; 107 (1): 117–22.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Halle C., Andersen E., Lando M., Aarnes E.K., Hasvold G., Holden M. et al. Hypoxia-induced gene expression in chemoradioresistant cervical cancer revealed by dynamic contrast-enhanced MRI. Cancer Res. 2012; 72 (20): 5285–95.</mixed-citation><mixed-citation xml:lang="en">Halle C., Andersen E., Lando M., Aarnes E.K., Hasvold G., Holden M. et al. Hypoxia-induced gene expression in chemoradioresistant cervical cancer revealed by dynamic contrast-enhanced MRI. Cancer Res. 2012; 72 (20): 5285–95.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Hompland T., Ellingsen C., Rofstad E.K. Preclinical evaluation of Gd-DTPA and gadomelitol as contrast agents in DCE-MRI of cervical carcinoma interstitial fluid pressure. BMC Cancer. 2012; 12: 544.</mixed-citation><mixed-citation xml:lang="en">Hompland T., Ellingsen C., Rofstad E.K. Preclinical evaluation of Gd-DTPA and gadomelitol as contrast agents in DCE-MRI of cervical carcinoma interstitial fluid pressure. BMC Cancer. 2012; 12: 544.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Kaur H., Silverman P.M., Iyer R.B., Verschraegen C.F., Eifel P.J., Charnsangavej C. Diagnosis, staging, and surveillance of cervical carcinoma. Am. J. Roentgenol. 2003; 180 (6): 1621–31.</mixed-citation><mixed-citation xml:lang="en">Kaur H., Silverman P.M., Iyer R.B., Verschraegen C.F., Eifel P.J., Charnsangavej C. Diagnosis, staging, and surveillance of cervical carcinoma. Am. J. Roentgenol. 2003; 180 (6): 1621–31.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Kaur H., Choi H., You Y.N., Rauch G.M., Jensen C.T., Hou P. et al. MR imaging for preoperative evaluation of primary rectal cancer: practical considerations. Radiographics. 2012; 32 (2): 389–409.</mixed-citation><mixed-citation xml:lang="en">Kaur H., Choi H., You Y.N., Rauch G.M., Jensen C.T., Hou P. et al. MR imaging for preoperative evaluation of primary rectal cancer: practical considerations. Radiographics. 2012; 32 (2): 389–409.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Rockall A.G., Sohaib S.A., Harisinghani M.G., Babar S.A., Singh N., Jeyarajah A.R. et al. Diagnostic performance of nanoparticle-enhanced magnetic resonance imaging in the diagnosis of lymph node metastases in patients with endometrial and cervical cancer. J. Clin. Oncol. 2005; 23 (12): 2813–21.</mixed-citation><mixed-citation xml:lang="en">Rockall A.G., Sohaib S.A., Harisinghani M.G., Babar S.A., Singh N., Jeyarajah A.R. et al. Diagnostic performance of nanoparticle-enhanced magnetic resonance imaging in the diagnosis of lymph node metastases in patients with endometrial and cervical cancer. J. Clin. Oncol. 2005; 23 (12): 2813–21.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Klerkx W.M., Veldhuis W.B., Spijkerboer A.M., van den Bosch M.A., Mali W.P., Heintz A.P. et al. The value of 3.0 Tesla diffusion-weighted MRI for pelvic nodal staging in patients with early stage cervical cancer. Eur. J. Cancer. 2012; 48 (18): 3414–21.</mixed-citation><mixed-citation xml:lang="en">Klerkx W.M., Veldhuis W.B., Spijkerboer A.M., van den Bosch M.A., Mali W.P., Heintz A.P. et al. The value of 3.0 Tesla diffusion-weighted MRI for pelvic nodal staging in patients with early stage cervical cancer. Eur. J. Cancer. 2012; 48 (18): 3414–21.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Shostka K.G., Pavlenko A.N., Fokina A.V., Kashina N.O., Roman L.D. Early and long-term results after pelvic exenterations of locally advanced cervical cancer. Voprosy onkologii. 2014; 60 (3): 319–22 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Shostka K.G., Pavlenko A.N., Fokina A.V., Kashina N.O., Roman L.D. Early and long-term results after pelvic exenterations of locally advanced cervical cancer. Voprosy onkologii. 2014; 60 (3): 319–22 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Padhani A.R., Liu G., Koh D.M., Chenevert T.L., Thoeny H.C., Takahara T. et al. Diffusion-weighted magnetic resonance imaging as a cancer biomarker: consensus and recommendations. Neoplasia. 2009; 11 (2): 102–25.</mixed-citation><mixed-citation xml:lang="en">Padhani A.R., Liu G., Koh D.M., Chenevert T.L., Thoeny H.C., Takahara T. et al. Diffusion-weighted magnetic resonance imaging as a cancer biomarker: consensus and recommendations. Neoplasia. 2009; 11 (2): 102–25.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Daar D.F., Bemardo M., Bernardo M.F., Choyke P.L., McKinney Y.M. et al. Prostate multiparameter MR imaging. Radiol. Technol. 2011; 6 (82): 563–8.</mixed-citation><mixed-citation xml:lang="en">Daar D.F., Bemardo M., Bernardo M.F., Choyke P.L., McKinney Y.M. et al. Prostate multiparameter MR imaging. Radiol. Technol. 2011; 6 (82): 563–8.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
