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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rentrad</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник рентгенологии и радиологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of radiology and nuclear medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4676</issn><issn pub-type="epub">2619-0478</issn><publisher><publisher-name>Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20862/0042-4676-2014-0-2-5-20</article-id><article-id custom-type="elpub" pub-id-type="custom">rentrad-9</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>ОСОБЕННОСТИ ИНТЕРПРЕТАЦИИ ПЕРФУЗИОННОЙ ОДНОФОТОННОЙ ЭМИССИОННОЙ КОМПЬЮТЕРНОЙ ТОМОГРАФИИ МИОКАРДА С КОМПЬЮТЕРНО-ТОМОГРАФИЧЕСКОЙ КОРРЕКЦИЕЙ ПОГЛОЩЕНИЯ</article-title><trans-title-group xml:lang="en"><trans-title>SPECIFIC FEATURES OF INTERPRETATION OF MYOCARDIAL PERFUSION SINGLE-PHOTON EMISSION COMPUTED TOMOGRAPHY WITH COMPUTED TOMOGRAPHIC ABSORPTION CORRECTION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аншелес</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ansheles</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к. м. н., н. с. отдела радионуклидной диагностики </p><p>ул. 3-я Черепковская, 15а, Москва, 121552</p></bio><bio xml:lang="en"><p>MD, PhD, Researcher of Nuclear Medicine Department</p><p>ul. Tret’ya Cherepkovskaya, 15a, Moscow, 121552</p></bio><email xlink:type="simple">a.ansheles@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Российский кардиологический научно-производственный комплекс» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Cardiology Research-and-Production Complex, Ministry of Health of the RF</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>27</day><month>02</month><year>2016</year></pub-date><volume>0</volume><issue>2</issue><fpage>5</fpage><lpage>20</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Аншелес А.А., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Аншелес А.А.</copyright-holder><copyright-holder xml:lang="en">Ansheles A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.russianradiology.ru/jour/article/view/9">https://www.russianradiology.ru/jour/article/view/9</self-uri><abstract><p>Цель исследования – изучить возможности совмещенной системы однофотонной эмиссионной компьютерной томографии (ОЭКТ)/КТ при выполнении перфузионного исследования миокарда, оценить влияние коррекции поглощения (attenuation correction – AC) и выявить факторы, влияющие на вклад AC в диагностический результат исследования.</p><sec><title>Материал и методы</title><p>Материал и методы. В исследование включены 167 пациентов, которым была выполнена перфузионная ОЭКТ миокарда с КТ-коррекцией поглощения и без нее. Визуально анализировались различия между AC- и non-AC-исследованиями, по итогам анализа сформированы группы визуальных различий. Предполагаемые факторы, влияющие на вклад AC, изучались с позиции отнесения в определенную группу визуальных различий.</p></sec><sec><title>Результаты</title><p>Результаты. Описаны возможные варианты влияния AC на результаты сцинтиграфии. Коррекция поглощения вносит значимый вклад в 68% случаев. В 80% этих случаев при AC восстанавливались дефекты перфузии, видимые при non-AC-исследовании. К факторам, предсказывающим существенные различия между AC- и non-AC-исследованиями, отнесены: масса тела, конечный диастолический объем, мужской пол, мелкоочаговые дефекты перфузии и преходящая ишемия, недостаточная активность введенного радиофармпрепарата. Такие факторы, как индекс массы тела, наличие крупных дефектов перфузии, настройки КТ-подсистемы и орбиты, время от введения радиофармпрепарата до начала исследования, не влияют существенно на вклад AC. При AC-исследованиях значения SRS и площади преходящей ишемии достоверно больше, чем при non-AC-исследованиях, что требует сдвига критериев нормы. Выявлены некоторые методические особенности интерпретации перфузионной ОЭКТ миокарда с КТ-коррекцией.</p></sec><sec><title>Заключение</title><p>Заключение. Проведение ОЭКТ миокарда с AC повышает диагностическую ценность метода, упрощает интерпретацию перфузионной ОЭКТ миокарда, снижает число ложноположительных и сомнительных результатов. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to study the capabilities of a hybrid single-photon emission computed tomography/computed tomography (SPECT/CT) system during myocardial perfusion imaging study, to evaluate the impact of absorption correction (AC), and to reveal factors influencing the contribution of AC to the diagnostic result of the study.</p></sec><sec><title>Material and methods</title><p>Material and methods. The study included 167 patients who underwent myocardial perfusion SPECT with and without CT AC. Differences between AC and non-AC studies were visually analyzed; the results of the analysis were used to form groups of visual differences. The supposed factors influencing the contribution of AC were studied, by assigning visual differences to a particular group.</p></sec><sec><title>Results</title><p>Results. The possible variants of the impact of AC were described in the baseline scintigrams. AC made a significant contribution in 68% of cases. With AC, the perfusion defects visible during non-AC study recovered in 80% of these cases. The factors predicting substantial differences between the AC and non-AC studies included weight, end diastolic volume, male sex, patients with small focal perfusion defects and transient ischemia, and inadequate injected activity. Factors, such as body mass index, large perfusion defects, CT subsystem and orbit settings, and time from the injection of a radiotracer to the initiation of a study, had no substantial impact on the contribution of AC. During AC studies, SRS and transient ischemic dilatation were significantly higher than during non-AC studies, requiring a shift of standard criteria. There were some methodical features of interpretation of myocardial perfusion SPECT using CT correction.</p></sec><sec><title>Conclusion</title><p>Conclusion. Myocardial SPECT with AC enhances the diagnostic value of the technique, simplifies the interpretation of myocardial perfusion SPECT, and reduces the number of falsepositive and questionable results.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>однофотонная эмиссионная компьютерная томография/ компьютерная томография</kwd><kwd>коррекция поглощения</kwd><kwd>миокард</kwd></kwd-group><kwd-group xml:lang="en"><kwd>single-photon emission computed tomography/computed tomography</kwd><kwd>absorption correction</kwd><kwd>myocardium</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Fanti S., Farsad M., Mansi L. Atlas of SPECT-CT: Springer; 2011.</mixed-citation><mixed-citation xml:lang="en">Fanti S., Farsad M., Mansi L. 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