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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rentrad</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник рентгенологии и радиологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of radiology and nuclear medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4676</issn><issn pub-type="epub">2619-0478</issn><publisher><publisher-name>Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20862/0042-4676-2024-105-4-202-207</article-id><article-id custom-type="elpub" pub-id-type="custom">rentrad-891</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORTS</subject></subj-group></article-categories><title-group><article-title>Редкий случай рецидивирующей липосаркомы забрюшинного пространства с метастазированием в мягкие ткани</article-title><trans-title-group xml:lang="en"><trans-title>A Rare Case of Recurrent Retroperitoneal Liposarcoma with Metastasis to Soft Tissues</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-9187-1390</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Магомедова</surname><given-names>У. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Magomedova</surname><given-names>U. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Магомедова Умамат Муртазалиевна, врач-рентгенолог </p><p>Коломенский пр-д, 4, Москва, 115446</p></bio><bio xml:lang="en"><p>Umamat М. Magomedova, Radiologist</p><p>Kolomenskiy proezd, 4, Moscow, 115446</p></bio><email xlink:type="simple">magomedovaum23@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6716-5593</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нечаев</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nechaev</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нечаев Валентин Александрович, к. м. н., заведующий центром комплексной диагностики </p><p>Коломенский пр-д, 4, Москва, 115446</p></bio><bio xml:lang="en"><p>Valentin А. Nechaev, Cand. Med. Sc., Head of Center for Complex Diagnostics</p><p>Kolomenskiy proezd, 4, Moscow, 115446</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0319-4934</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куликова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulikova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Куликова Евгения Александровна, заведующая отделением лучевой диагностики </p><p>Коломенский пр-д, 4, Москва, 115446</p></bio><bio xml:lang="en"><p>Evgenia А. Kulikova, Head of Department of Radiation Diagnostics</p><p>Kolomenskiy proezd, 4, Moscow, 115446</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0310-0889</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юдин</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Yudin</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юдин Андрей Леонидович, д. м. н., профессор, заведующий кафедрой лучевой диагностики и терапии медико-биологического факультета </p><p>ул. Островитянова, 1, Москва, 117513</p></bio><bio xml:lang="en"><p>Аndrey L. Yudin, Dr. Med. Sc., Professor, Chief of Chair of Radiation Diagnostics and Therapy, Faculty of Medicine and Biology</p><p>ul. Ostrovityanova, 1, Moscow, 117513</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6020-9434</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юматова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yumatova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юматова Елена Анатольевна, к. м. н., доцент кафедры лучевой диагностики и терапии медико-биологического факультета </p><p>ул. Островитянова, 1, Москва, 117513</p></bio><bio xml:lang="en"><p>Еlena А. Yumatova, Cand. Med. Sc., Associate Professor, Chair of Radiation Diagnostics and Therapy, Faculty of Medicine and Biology</p><p>ul. Ostrovityanova, 1, Moscow, 117513</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ «Городская клиническая больница им. С.С. Юдина ДЗМ»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Yudin City Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>19</day><month>02</month><year>2025</year></pub-date><volume>105</volume><issue>4</issue><fpage>202</fpage><lpage>207</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Магомедова У.М., Нечаев В.А., Куликова Е.А., Юдин А.Л., Юматова Е.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Магомедова У.М., Нечаев В.А., Куликова Е.А., Юдин А.Л., Юматова Е.А.</copyright-holder><copyright-holder xml:lang="en">Magomedova U.M., Nechaev V.A., Kulikova E.A., Yudin A.L., Yumatova E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.russianradiology.ru/jour/article/view/891">https://www.russianradiology.ru/jour/article/view/891</self-uri><abstract><p>В статье представлен клинический случай рецидивирующей липосаркомы забрюшинного пространства с редко встречающимся типом отдаленного метастазирования в мягкие ткани на фоне проводимого хирургического и химиотерапевтического лечения. Проанализированы история болезни и результаты компьютерной томографии (КТ) пациента, находящегося на лечении и диспансерном наблюдении в филиале «Онкологический центр № 1» ГБУЗ «Городская клиническая больница им. С.С. Юдина ДЗМ» с мая 2021 г. по настоящее время. Применение КТ остается чрезвычайно важным этапом обследования больных с забрюшинной липосаркомой для оценки местной распространенности опухоли и выявления отдаленных вторичных очагов поражения, в том числе в мягких тканях.</p></abstract><trans-abstract xml:lang="en"><p>The article describes a clinical case of recurrent retroperitoneal liposarcoma with a rare type of distant metastasis in a patient undergoing surgical and chemotherapy treatment in Cancer Center No. 1 (branch of Yudin City Clinical Hospital) since May 2021. The patient's medical history and computed tomography (CT) results were analyzed. The use of CT remains an extremely important stage in the examination of patients with retroperitoneal liposarcoma for assessing local prevalence, identifying distant secondary lesions, including ones to soft tissues.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>липосаркома забрюшинного пространства</kwd><kwd>рецидив</kwd><kwd>дедифференцированная липосаркома</kwd><kwd>компьютерная томография</kwd><kwd>КТ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>retroperitoneal liposarcoma</kwd><kwd>relapse</kwd><kwd>dedifferentiated liposarcoma</kwd><kwd>computed tomography</kwd><kwd>CT</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Dehner CA, Hagemann IS, Chrisinger JSA. Retroperitoneal dedifferentiated liposarcoma. Am J Clin Pathol. 2021; 156 (5): 920–5. https://doi.org/10.1093/ajcp/aqab051.</mixed-citation><mixed-citation xml:lang="en">Dehner CA, Hagemann IS, Chrisinger JSA. Retroperitoneal dedifferentiated liposarcoma. Am J Clin Pathol. 2021; 156 (5): 920–5. https://doi.org/10.1093/ajcp/aqab051.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Волков А.Ю., Неред С.Н., Козлов Н.А. и др. Прогностические группы при забрюшинных высокодифференцированных и дедифференцированных липосаркомах. Медицинский совет. 2021; 4S: 94–102. https://doi.org/10.21518/2079-701X2021-4S-94-102.</mixed-citation><mixed-citation xml:lang="en">Volkov АYu, Nered SN, Kozlov NА, et al. Prognostic groups in retroperitoneal well-differentiated and dedifferentiated liposarcomas. Meditsinskiy sovet / Medical Council. 2021; 4S: 94–102 (in Russ). https://doi.org/10.21518/2079-701X-2021-4S-94-102.]</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Волков А.Ю., Неред С.Н., Любченко Л.Н. Забрюшинные неорганные липосаркомы: современный взгляд на проблему. Сибирский онкологический журнал. 2019; 18(5): 86–96. https://doi.org/10.21294/1814-4861-2019-185-86-96.</mixed-citation><mixed-citation xml:lang="en">Volkov AYu, Nered SN, Lyubchenko LN. Retroperitoneal nonorgan liposarcomas: the modern concept. Siberian Journal of Oncology. 2019; 18(5): 86–96 (in Russ). https://doi.org/10.21294/1814-4861-2019-18-5-86-96.]</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Jolissaint JS, Raut CP, Fairweather M. Management of recurrent retroperitoneal sarcoma. Curr Oncol. 2023; 30(3): 2761–9. https://doi.org/10.3390/curroncol30030209.</mixed-citation><mixed-citation xml:lang="en">Jolissaint JS, Raut CP, Fairweather M. Management of recurrent retroperitoneal sarcoma. Curr Oncol. 2023; 30(3): 2761–9. https://doi.org/10.3390/curroncol30030209.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Improta L, Tzanis D, Bouhadiba T, et al. Overview of primary adult retroperitoneal tumours. Eur J Surg Oncol. 2020; 46(9): 1573–9. https://doi.org/10.1016/j.ejso.2020.04.054.</mixed-citation><mixed-citation xml:lang="en">Improta L, Tzanis D, Bouhadiba T, et al. Overview of primary adult retroperitoneal tumours. Eur J Surg Oncol. 2020; 46(9): 1573–9. https://doi.org/10.1016/j.ejso.2020.04.054.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Casciani E, Polettini E, Sollaku S, et al. Imaging of primary retroperitoneal neoplasms. Ann Ital Chir. 2022; 93: 489–503.</mixed-citation><mixed-citation xml:lang="en">Casciani E, Polettini E, Sollaku S, et al. Imaging of primary retroperitoneal neoplasms. Ann Ital Chir. 2022; 93: 489–503.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Petronella P, Scorzelli M, Iannacci G. Clinical considerations on the retroperitoneal liposarcomas. Ann Ital Chir. 2012; 83(1): 35–9.</mixed-citation><mixed-citation xml:lang="en">Petronella P, Scorzelli M, Iannacci G. Clinical considerations on the retroperitoneal liposarcomas. Ann Ital Chir. 2012; 83(1): 35–9.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Masaki N, Onozawa M, Inoue T, et al. Clinical features of multiply recurrent retroperitoneal liposarcoma: a singlecenter experience. Asian J Surg. 2021; 44(1): 380–5. https://doi.org/10.1016/j.asjsur.2020.10.015.</mixed-citation><mixed-citation xml:lang="en">Masaki N, Onozawa M, Inoue T, et al. Clinical features of multiply recurrent retroperitoneal liposarcoma: a singlecenter experience. Asian J Surg. 2021; 44(1): 380–5. https://doi.org/10.1016/j.asjsur.2020.10.015.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Yoshida K, Yoshida M, Haisa M, et al. A case report of left lower lobe segmentectomy for pulmonary metastasis from retroperitoneal liposarcoma. Int J Surg Case Rep. 2019; 61: 169–73. https://doi.org/10.1016/j.ijscr.2019.07.059.</mixed-citation><mixed-citation xml:lang="en">Yoshida K, Yoshida M, Haisa M, et al. A case report of left lower lobe segmentectomy for pulmonary metastasis from retroperitoneal liposarcoma. Int J Surg Case Rep. 2019; 61: 169–73. https://doi.org/10.1016/j.ijscr.2019.07.059.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Tseng WW, Madewell JE, Wei W, et al. Locoregional disease patterns in well-differentiated and dedifferentiated retroperitoneal liposarcoma: implications for the extent of resection? Ann Surg Oncol. 2014; 21(7): 2136–43. https://doi.org/10.1245/s10434-014-3643-4.</mixed-citation><mixed-citation xml:lang="en">Tseng WW, Madewell JE, Wei W, et al. Locoregional disease patterns in well-differentiated and dedifferentiated retroperitoneal liposarcoma: implications for the extent of resection? Ann Surg Oncol. 2014; 21(7): 2136–43. https://doi.org/10.1245/s10434-014-3643-4.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Huang HY, Brennan M, Singer S, Antonescu CR. Distant metastasis in retroperitoneal dedifferentiated liposarcoma is rare and rapidly fatal: a clinicopathological study with emphasis on the low-grade myxofibrosarcoma-like pattern as an early sign of dedifferentiation. Mod Pathol. 2005; 18(7): 976–84. https://doi.org/10.1038/modpathol.3800381.</mixed-citation><mixed-citation xml:lang="en">Huang HY, Brennan M, Singer S, Antonescu CR. Distant metastasis in retroperitoneal dedifferentiated liposarcoma is rare and rapidly fatal: a clinicopathological study with emphasis on the low-grade myxofibrosarcoma-like pattern as an early sign of dedifferentiation. Mod Pathol. 2005; 18(7): 976–84. https://doi.org/10.1038/modpathol.3800381.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
