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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rentrad</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник рентгенологии и радиологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of radiology and nuclear medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4676</issn><issn pub-type="epub">2619-0478</issn><publisher><publisher-name>Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20862/0042-4676-2023-104-2-115-123</article-id><article-id custom-type="elpub" pub-id-type="custom">rentrad-793</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Магнитно-резонансная томография в диагностике нарушений эластических свойств стенки аорты и ее гемодинамики</article-title><trans-title-group xml:lang="en"><trans-title>Magnetic Resonance Imaging in the Diagnosis of Aortic Wall Elastic Properties Disorders and Its Hemodynamics</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8789-0330</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бриль</surname><given-names>К. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Bril</surname><given-names>K. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бриль Кристина Руслановна, аспирант,</p><p>Абрикосовский пер., 2, Москва, 119991</p></bio><bio xml:lang="en"><p>Kristina R. Bril, Postgraduate, </p><p>Abrikosovskiy per., 2, Moscow, 119991</p></bio><email xlink:type="simple">kr.bril@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8091-9479</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пронкин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pronkin</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пронкин Александр Артурович, к. т. н., ст. науч. сотр., ул. Ижорская, 13, стр. 2, Москва, 125412;</p><p>ул. Красноказарменная, 14, стр.1, Москва, 111250</p></bio><bio xml:lang="en"><p>Alexander A. Pronkin, Cand. Tech. Sc., Senior Researcher, ul. Izhorskaya, 13, str. 2, Moscow, 125412;</p><p>ul. Krasnokazarmennaya, 14, str. 1, Moscow, 111250</p><p> </p><p> </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4751-5119</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галян</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Galyan</surname><given-names>T. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Галян Татьяна Николаевна, к. м. н., заведующая отделением рентгенодиагностики и компьютерной томографии,</p><p>Абрикосовский пер., 2, Москва, 119991</p></bio><bio xml:lang="en"><p>Tatiana N. Galyan, Cand. Med. Sc., Head of Department of Radiology and Computed Tomography, </p><p>Abrikosovskiy per., 2, Moscow, 119991</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6720-4126</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ховрин</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Khovrin</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ховрин Валерий Владиславович, д. м. н., гл. науч. сотр.,</p><p>Абрикосовский пер., 2, Москва, 119991</p></bio><bio xml:lang="en"><p>Valeriy V. Khovrin, Dr. Med. Sc., Chief Researcher,</p><p>Abrikosovskiy per., 2, Moscow, 119991</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Российский научный центр хирургии им. акад. Б.В. Петровского»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Petrovsky Russian Scientific Center of Surgery</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУН «Объединенный институт высоких температур» Российской академии наук;&#13;
ФГБОУ «Национальный исследовательский университет «Московский энергетический институт»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Joint Institute of High Temperatures, Russian Academy of Sciences;&#13;
National Research University “Moscow Power Engineering Institute”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>05</day><month>08</month><year>2023</year></pub-date><volume>104</volume><issue>2</issue><fpage>115</fpage><lpage>123</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бриль К.Р., Пронкин А.А., Галян Т.Н., Ховрин В.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Бриль К.Р., Пронкин А.А., Галян Т.Н., Ховрин В.В.</copyright-holder><copyright-holder xml:lang="en">Bril K.R., Pronkin A.A., Galyan T.N., Khovrin V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.russianradiology.ru/jour/article/view/793">https://www.russianradiology.ru/jour/article/view/793</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Жесткость сосудистой стенки – важный предиктор сердечно-сосудистых заболеваний. Биомеханические показатели сосудистой стенки изменяются не только у пациентов с генетическими нарушениями соединительной ткани. Это значит, что, независимо от этиологии, выявление прогрессивной потери аортальной эластичности на ранних этапах имеет большую клиническую значимость для предотвращения развития грозных осложнений. Оценка биомеханических параметров аорты с помощью магнитно-резонансной томографии (МРТ) является новым уровнем визуализации заболеваний аорты, позволяющим совершенствовать хирургическую тактику и предупреждать развитие осложнений. Ряд определяемых при МРТ аорты биомеханических и гемодинамических параметров демонстрирует процесс ремоделирования ее стенки, поэтому их анализ дает возможность разработать алгоритм ранней диагностики аневризмы и угрозы возникновения острого аортального синдрома.</p></sec><sec><title>Цель</title><p>Цель: с помощью данных МРТ аорты оценить ее биомеханические параметры и гемодинамику на дои послеоперационном этапах и их влияние на возникновение осложнений и рецидивов в отдаленном периоде.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В период с 2020 по 2023 гг. В РНЦХ им. акад. Б.В. Петровского проспективно была выполнена МРТ аорты 107 пациентам с диагнозами «аневризма восходящей аорты» (55 человек: 48 (87%) мужчин и 7 (13%) женщин, средний возраст 79,4±14,91 года) и «расслоение аорты I и III типов по De Bakey, хроническая стадия» (52 пациента: 44 (85%) мужчины и 8 (15%) женщин, средний возраст 54,32±10,41 года). Исследование проводилось до и после операции.</p></sec><sec><title>Результаты</title><p>Результаты. При количественном анализе полученных данных у обследуемых пациентов в послеоперационном периоде наблюдалось снижение эластических свойств стенки аорты в виде растяжимости (0,4 [0,34; 0,54] %/мм рт. ст. в группе с аневризмой; 0,5 [0,25; 0,55] %/мм рт. ст. в группе с расслоением) и увеличение показателя жесткости в виде модуля Юнга (0,6 [0,38; 0,68] мПа в группе с аневризмой; 0,5 [0,39; 0,83] мПа в группе с расслоением). По результатам оценки гемодинамических изменений в группе с расслоением после операции продемонстрировано значительное увеличение показателей максимальной скорости в нисходящей аорте (78,6 [66,24; 130,78] см/с) и градиента давления на уровне чревного ствола (2,1 [1,76; 6,84] мм рт. ст.). При оценке параметра скорости пульсовой волны в обеих группах отмечены высокие значения с тенденцией к увеличению после выполнения хирургического лечения (в группе аневризмы 7,7 [5,7; 20,3] см/с до операции против 8,7 [6,5; 10,65] см/с после операции; в группе расслоения 9,7 [6,8; 12,9] против 12,7 [7,7; 15,7] см/с соответственно).</p></sec><sec><title>Заключение</title><p>Заключение. Мониторинг общей гемодинамики и паттернов кровотока совместно с оценкой эластичности стенки аорты позволит выявлять пациентов с пограничной дилатацией аорты. При этом особый интерес вызывают исследования протезированного сегмента аорты. Полученные данные гемодинамических изменений, возникающих на границе протезированного и нативного сегментов оперированной аорты, могут подтвердить и обосновать развитие осложнения в виде надрыва интимы по дистальному краю стента-графта (distal stent graft-induced new entry, dSINE).</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. Vascular stiffness is an important predictor of cardiovascular disease. The vascular wall biomechanical parameters change not only in patients with genetic disorders of the connective tissue. This means that, regardless of etiology, the early detection of a progressive loss of aortic elasticity is of great clinical importance in preventing the development of severe complications. Assessment of aortic biomechanical parameters using magnetic resonance imaging (MRI) is a new level of visualization for aortic diseases allowing to improve surgical tactics and prevent complications. A number of biomechanical parameters determined by aortic MRI demonstrates the process of its wall remodeling, so their analysis will allow to develope an algorithm for the early diagnosis of aneurysms and the threat of acute aortic syndrome.</p></sec><sec><title>Objective</title><p>Objective: using aortic MRI data, to evaluate the aortic biomechanical parameters and hemodynamics at pre- and postoperative stages and their impact on the occurrence of complications and relapses in the long-term period.</p></sec><sec><title>Material and methods</title><p>Material and methods. Between 2020 and 2023, in Petrovsky Russian Scientific Center of Surgery, aortic MRI was performed prospectively before and after surgery in 107 patients with diagnoses of ascending aortic aneurysm (55 patients: 48 (87%) males and 7 (13%) females, mean age 79.4±14.91 years) and DeBakey type I and III aortic dissection, chronic stage (52 patients: 44 (85%) males and 8 (15%) females, mean age 54.32±10.41 years).</p></sec><sec><title>Results</title><p>Results. The quantitative data analysis in the postoperative period showed a decrease in the aortic wall elastic properties in the form of extensibility (0.4 [0.34; 0.54] %/mm Hg in the aneurysm group; 0.5 [0.25; 0.55] %/mmHg in the dissection group) and an increase in stiffness in the form of Young’s modulus (0.6 [0.38; 0.68] MPa in the aneurysm group; 0.5 [0.39; 0.83] MPa in the dissection group). Hemodynamic changes in the dissection group after surgery demonstrated a significant increase in values of maximum velocity in the descending aorta (78.6 [66.24; 130.78] cm/sec) and pressure gradient at the celiac trunk level (2.10 [1.76; 6.84] mm Hg). When assessing the pulse wave velocity parameter in both groups, high values were noted with a tendency to increase after surgery (in the aneurysm group, 7.7 [5.7; 20.3] cm/s before surgery versus 8.7 [6.5; 10.65] cm/s after surgery; in the dissection group, 9.7 [6.8; 12.9] versus 12.7 [7.7; 15.7] cm/s, respectively).</p></sec><sec><title>Conclusion</title><p>Conclusion. Monitoring general hemodynamics and blood flow patterns together with an assessment of the aortic wall elasticity will make it possible to identify patients with borderline aortic dilatation. At the same time, studies of the aortic prosthetic segment are of particular interest. The obtained data on hemodynamic changes occuring at the border of the prosthetic and native segments of the operated aorta can confirm and justify the development of a complication in the form of distal stent graft-induced new entry (dSINE).</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>магнитно-резонансная томография аорты</kwd><kwd>аневризма аорты</kwd><kwd>расслоение аорты</kwd><kwd>жесткость стенки аорты</kwd><kwd>эластичность аорты</kwd><kwd>модуль Юнга</kwd><kwd>скорость пульсовой волны.</kwd></kwd-group><kwd-group xml:lang="en"><kwd>aortic magnetic resonance imaging</kwd><kwd>aortic aneurysm</kwd><kwd>aortic dissection</kwd><kwd>aortic wall stiffness</kwd><kwd>aortic elasticity</kwd><kwd>Young’s modulus</kwd><kwd>pulse wave velocity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Jannasz I, Sondej T, Targowski T, et al. 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