rentradВестник рентгенологии и радиологииJournal of radiology and nuclear medicine0042-46762619-0478Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists10.20862/0042-4676-2021-102-3-196-202rentrad-651Research ArticleОБЗОРЫREVIEWSОценка сосудистых кальцинатов молочной железы как предиктора кальциноза коронарных артерийEvaluation of Breast Vascular Calcifications as a Predictor for Coronary Artery Calcificationhttps://orcid.org/0000-0002-7757-6273БаженоваД. А.BazhenovaD. A.

Баженова Дарья Анатольевна, аспирант кафедры лучевой диагностики и терапии факультета фундаментальной медицины, врач-рентгенолог отделения рентгенодиагностики с кабинетами компьютерной и магнитно-резонансной томографии

Ломоносовский пр-т, 27, корп. 10, Москва, 119192

Darya А. Bazhenova, Postgrsduate, Chair of Radiation Diagnostics and Therapy, Faculty of Fundamental Medicine; Radiologist, X-Ray Diagnostics Department with Computer and Magnetic Resonance Imaging Rooms

Lomonosovskiy prospect, 27, corp. 10, Moscow, 119192

bazhenova.darya@gmail.comhttps://orcid.org/0000-0002-1182-1002ПучковаО. С.PuchkovaO. S.

Пучкова Ольга Сергеевна, врач-рентгенолог отделения рентгенодиагностики с кабинетами компьютерной и магнитнорезонансной томографии

Ломоносовский пр-т, 27, корп. 10, Москва, 119192

Olga S. Puchkova, Radiologist, X-Ray Diagnostics Department with Computer and Magnetic Resonance Imaging Rooms

Lomonosovskiy prospect, 27, corp. 10, Moscow, 119192

https://orcid.org/0000-0002-1266-4926МершинаЕ. А.MershinaE. A.

Мершина Елена Александровна, доцент кафедры лучевой диагностики и терапии факультета фундаментальной медицины, заведующая отделением рентгенодиагностики с кабинетами компьютерной и магнитно-резонансной томографии

Ломоносовский пр-т, 27, корп. 10, Москва, 119192

Elena А. Mershina, Associate Professor, Chair of Radiation Diagnostics and Therapy, Faculty of Fundamental Medicine; Head of X-Ray Diagnostics Department with Computer and Magnetic Resonance Imaging Rooms

Lomonosovskiy prospect, 27, corp. 10, Moscow, 119192

https://orcid.org/0000-0002-5649-2193СиницынВ. Е.SinitsynV. E.

Синицын Валентин Евгеньевич, доктор медицинских наук, профессор, заведующий кафедрой лучевой диагностики и терапии факультета фундаментальной медицины, заведующий отделом лучевой диагностики

Ломоносовский пр-т, 27, корп. 10, Москва, 119192

Valentin Е. Sinitsyn, Dr. Med. Sc., Professor, Chief of Chair of Radiation Diagnostics and Therapy, Faculty of Fundamental Medicine; Head of Department of Radiation Diagnostics

Lomonosovskiy prospect, 27, corp. 10, Moscow, 119192

Медицинский научно-образовательный центр ФГБОУ ВО «Московский государственный университет им. М.В. Ломоносова»РоссияMedical Research and Educational Center, Lomonosov Moscow State UniversityRussian Federation2021230720211023196202Copyright © Баженова Д.А., Пучкова О.С., Мершина Е.А., Синицын В.Е., 20212021Баженова Д.А., Пучкова О.С., Мершина Е.А., Синицын В.Е.Bazhenova D.A., Puchkova O.S., Mershina E.A., Sinitsyn V.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.russianradiology.ru/jour/article/view/651Актуальность

Актуальность. Сердечно-сосудистые заболевания являются одной из основных причиной смерти среди женщин, и современные парадигмы профилактики могут быть недостаточными в этой группе. В данном контексте было выдвинуто предположение, что выявление сосудистых кальцинатов в молочной железе может улучшить скрининг и оценку риска сердечно-сосудистых заболеваний у практически здоровых женщин.

Цель

Цель: изучение роли кальцинатов в сосудах молочной железы как потенциального предиктора кальциноза коронарных артерий.

Материал и методы

Материал и методы. Были обследованы 123 пациентки, которым выполняли цифровую маммографию и компьютерную томографию сердца для оценки кальциевого индекса в коронарных артериях.

Результаты

Результаты. Применение W-критерия Уилкоксона–Манна–Уитни при ненормальном распределении показало взаимосвязь между наличием сосудистых кальцинатов в молочной железе и кальциевым индексом (p < 0,001), кальцинозом стенки аорты и кальциевым индексом (p < 0,001).

Заключение

Заключение. Сосудистые кальцинаты в молочной железе, определяемые при маммографии, являются показателем более высокой частоты развития кальциноза коронарных артерий и, по-видимому, предиктором повышенного риска сердечно-сосудистых заболеваний.

Background

Background. Cardiovascular diseases are one of the main causes of death among women, and current prevention paradigms may not be sufficient in this group. In this context, it has been suggested that the detection of breast vascular calcifications can improve the screening and assessment of the risk of cardiovascular diseases in apparently healthy women.

Objective

Objective: to study the role of breast vascular calcifications as a potential predictor for coronary artery calcification. Material and methods. Examinations were made in 123 patients who underwent digital mammography and cardiac computed tomography to estimate a coronary artery calcium score.

Results

Results. The use of the Wilcoxon-Mann-Whitney W-test for abnormal distribution showed a relationship between the presence of breast vascular calcifications and calcium score (p< 0.001), and that between aortic wall calcification and calcium score (p< 0.001).

Conclusion

Conclusion. Breast vascular calcifications detected by mammography are an indicator of a higher frequency of coronary artery calcification and, apparently, a predictor for the increased risk of cardiovascular disease.

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The authors declare that there are no conflicts of interest present.