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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rentrad</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник рентгенологии и радиологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of radiology and nuclear medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4676</issn><issn pub-type="epub">2619-0478</issn><publisher><publisher-name>Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20862/0042-4676-2021-102-3-155-165</article-id><article-id custom-type="elpub" pub-id-type="custom">rentrad-646</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Визуализация рака желудка: компьютерно-томографическая пневмогастрография</article-title><trans-title-group xml:lang="en"><trans-title>Gastric Cancer Imaging: Computed Tomographic Pneumogastrography</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5128-001X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Амелина</surname><given-names>И. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Amelina</surname><given-names>I. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Амелина Инна Дмитриевна, младший научный сотрудник научного отделения диагностической и интервенционной радиологии, врач-рентгенолог</p><p>ул. Ленинградская, 68, пос. Песочный, Санкт-Петербург, 197758</p></bio><bio xml:lang="en"><p>Inna D.Amelina, Junior Researcher, Scientific Department of Diagnostic and Interventional Radiology, Radiologist</p><p>ul. Leningradskaya, 68, poselok Pesochnyy, Saint Petersburg, 197758</p></bio><email xlink:type="simple">dr.innamelina@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4533-1658</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шевкунов</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shevkunov</surname><given-names>L. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шевкунов Лев Николаевич, кандидат медицинских наук, заведующий отделением лучевой диагностики, старший научный сотрудник. научного отделения диагностической и интервенционной радиологии, врач-рентгенолог</p><p>ул. Ленинградская, 68, пос. Песочный, Санкт-Петербург, 197758</p></bio><bio xml:lang="en"><p>Lev N. Shevkunov, Cand. Med. Sc., Head of Radiation Diagnostics Department, Senior Researcher, Scientific Department of Diagnostic and Interventional Radiology, Radiologist</p><p>ul. Leningradskaya, 68, poselok Pesochnyy, Saint Petersburg, 197758</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6641-7229</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карачун</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Karachun</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Карачун Алексей Михайлович, доктор медицинских наук, доцент, заведующий отделением абдоминальной онкологии, руководитель научного отделения опухолей желудочно-кишечного тракта, врач-онколог</p><p>ул. Ленинградская, 68, пос. Песочный, Санкт-Петербург, 197758</p></bio><bio xml:lang="en"><p>Aleksey M. Karachun, Dr. Med. Sc., Associate Professor, Head of Department of Abdominal Oncology, Head of Scientific Department of Gastrointestinal Tumors, Oncologist</p><p>ul. Leningradskaya, 68, poselok Pesochnyy, Saint Petersburg, 197758</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Муравцева</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Muravtseva</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Муравцева Анастасия Леонидовна, врач-патологоанатом</p><p>ул. Ленинградская, 68, пос. Песочный, Санкт-Петербург, 197758</p></bio><bio xml:lang="en"><p>Anastasiya L. Muravtseva, Pathologist, Petrov National Medical Research Center for Oncology</p><p>ul. Leningradskaya, 68, poselok Pesochnyy, Saint Petersburg, 197758</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2948-397X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Артемьева</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Artemyeva</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Артемьева Анна Сергеевна, кандидат медицинских наук, доцент, заведующая патологоанатомическим отделением, руководитель научной лаборатории морфологии опухолей</p><p>ул. Ленинградская, 68, пос. Песочный, Санкт-Петербург, 197758</p></bio><bio xml:lang="en"><p>Anna S. Artemyeva, Cand. Med. Sc., Associate Professor, Head of Pathological Department, Head of Scientific Laboratory of Tumor Morphology</p><p>ul. Leningradskaya, 68, poselok Pesochnyy, Saint Petersburg, 197758</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Петрова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Petrov National Medical Research Center for Oncology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>22</day><month>07</month><year>2021</year></pub-date><volume>102</volume><issue>3</issue><fpage>155</fpage><lpage>165</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Амелина И.Д., Шевкунов Л.Н., Карачун А.М., Муравцева А.Л., Артемьева А.С., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Амелина И.Д., Шевкунов Л.Н., Карачун А.М., Муравцева А.Л., Артемьева А.С.</copyright-holder><copyright-holder xml:lang="en">Amelina I.D., Shevkunov L.N., Karachun A.M., Muravtseva A.L., Artemyeva A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.russianradiology.ru/jour/article/view/646">https://www.russianradiology.ru/jour/article/view/646</self-uri><abstract><sec><title>Цель</title><p>Цель: раскрыть технические нюансы для получения качественных изображений с помощью протокола компьютерной томографии с пневмогастрографией и виртуальной гастроскопией, способствующие выявлению, оценке морфологического типа, определению локализации, глубины инвазии рака желудка.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В исследование вошли 250 пациентов как с ранним (24,8%), так и с местнораспространенным (75,2%) раком желудка, получавших лечение в Национальном медицинском исследовательском центре онкологии имени Н.Н. Петрова с 2015 по 2018 г. Предоперационную химиотерапию прошли 142 (56,8%) пациента, 108 (43,2%) больных ее не получали. Всем пациентам на предоперационном этапе была проведена компьютерная томография с пневмогастрографией и виртуальной гастроскопией. Все больные были радикально прооперированы в объеме субтотальной или тотальной резекции желудка.</p></sec><sec><title>Результаты</title><p>Результаты. Методом компьютерной томографии с пневмогастрографией и виртуальной гастроскопией рак желудка был обнаружен в 98,4% случаев, 23,2% составили случаи раннего рака с глубиной инвазии Т1а и Т1b. У 4 (1,6%) пациентов опухоль достоверно дифференцировать не удалось. Данную группу составили: 3 (1,2%) больных с опухолью глубиной инвазии рТ1а и 1 (0,4%) пациент с рТ1b. Все невизуализируемые образования имели поверхностный морфологический тип роста: тип 0–II (3 случая с типом 0–IIa и 1 случай с типом 0–IIb), размеры менее 2 см. Три образования локализовались в антральном отделе желудка, 1 – в кардиальном отделе желудка.</p></sec><sec><title>Заключение</title><p>Заключение. Компьютерная томография с пневмогастрографией и виртуальной гастроскопией – эффективный метод выявления рака желудка, в том числе ранних форм категории Т1, позволяющий оценить локализацию, морфологический тип и глубину инвазии опухоли.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to reveal technical nuances for obtaining high-quality images using a computed tomography protocol with pneumogastrography and virtual gastroscopy, which contribute to the detection and assessment of the morphological type of gastric cancer and to the determination of its localization and invasion depth.</p></sec><sec><title>Material and methods</title><p>Material and methods. The investigation enrolled 250 patients with both early (24.8%) and locally advanced (75.2%) gastric cancer treated in Petrov National Medical Research Center for Oncology from 2015 to 2018. Preoperative chemotherapy was performed in 142 (56.8%) patients and was not done in 108 (43.2%). All the patients underwent preoperative computed tomography with pneumogastrography and virtual gastroscopy. All the patients were radically operated on through subtotal or total gastric resection.</p></sec><sec><title>Results</title><p>Results. Computed tomography with pneumogastrography and virtual gastroscopy was used to detect gastric cancer in 98.4% of patients; the cases with early T1a and T1b invasion depth cancers were 23.2%. The tumor could not be significantly differentiated in 4 (1.6%) patients. This group consisted of: 3 (1.2%) and 1 (0.4%) patients with pT1a and pT1b invasion depth tumors, respectively. All non-visualized tumors had a superficial morphological type of growth (Type 0–II (3 cases with 0–IIa and 1 case with 0–IIb); their sizes were less than 2 cm. Three tumors were localized in the antral portion of the stomach; one was in its cardiac portion.</p></sec><sec><title>Conclusion</title><p>Conclusion. Computed tomography with pneumogastrography and virtual gastroscopy is an effective technique to detect gastric cancer, including its early types of category T1, which makes it possible to assess its localization, morphological type, and invasion depth.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>рак желудка</kwd><kwd>ранний рак желудка</kwd><kwd>протокол сканирования</kwd><kwd>компьютерно-томографическая семиотика</kwd><kwd>глубина инвазии</kwd><kwd>компьютерно-томографическая пневмогастрография</kwd><kwd>виртуальная гастроскопия</kwd><kwd>Т-стадия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gastric cancer</kwd><kwd>early gastric cancer</kwd><kwd>scanning protocol</kwd><kwd>computed tomographic semiotics</kwd><kwd>depth of invasion</kwd><kwd>computed tomographic pneumogastrography</kwd><kwd>virtual gastroscopy</kwd><kwd>T stage</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cancer Facts &amp; Figures 2020. Atlanta: American Cancer Society. Available at: https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-andfigures/2020/cancer-facts-and-figures-2020.pdf (accessed May 27, 2021).</mixed-citation><mixed-citation xml:lang="en">Cancer Facts &amp; Figures 2020. Atlanta: American Cancer Society. Available at: https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-andfigures/2020/cancer-facts-and-figures-2020.pdf (accessed May 27, 2021).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018; 392(10159): 1859–922. https://doi.org/10.1016/S0140-6736(18)32335-3.</mixed-citation><mixed-citation xml:lang="en">Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018; 392(10159): 1859–922. https://doi.org/10.1016/S0140-6736(18)32335-3.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Plummer M, Martel C, Vignat J, et al. Global burden of cancers attributable to infections in 2012: a synthetic analysis. Lancet Glob Health. 2016; 4(9): e609–16. https://doi.org/10.1016/S2214-109X(16)30143-7.</mixed-citation><mixed-citation xml:lang="en">Plummer M, Martel C, Vignat J, et al. Global burden of cancers attributable to infections in 2012: a synthetic analysis. Lancet Glob Health. 2016; 4(9): e609–16. https://doi.org/10.1016/S2214-109X(16)30143-7.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Lin JT. Screening of gastric cancer: who, when, and how. Clin Gastroenterol Hepatol. 2014; 12(1): 135–8. https://doi.org/10.1016/j.cgh.2013.09.064.</mixed-citation><mixed-citation xml:lang="en">Lin JT. Screening of gastric cancer: who, when, and how. Clin Gastroenterol Hepatol. 2014; 12(1): 135–8. https://doi.org/10.1016/j.cgh.2013.09.064.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Pasechnikov V, Chukov S, Fedorov E, et al. Gastric cancer: prevention, screening and early diagnosis. World J Gastroenterol. 2014; 20(38): 13842–62. https://doi.org/10.3748/wjg.v20.i38.13842.</mixed-citation><mixed-citation xml:lang="en">Pasechnikov V, Chukov S, Fedorov E, et al. Gastric cancer: prevention, screening and early diagnosis. World J Gastroenterol. 2014; 20(38): 13842–62. https://doi.org/10.3748/wjg.v20.i38.13842.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Мерабишвили В.М. Рак желудка: эпидемиология, профилактика, оценка эффективности лечения на популяционном уровне. Практическая онкология. 2001; 3(7): 3–8.</mixed-citation><mixed-citation xml:lang="en">Merabishvili VM. Gastric cancer: epidemiology, prevention, assessment of the effectiveness of treatment at the population level. Practical Oncology. 2001; 3(7): 3–8 (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Yu JS, Choi SH, Choi WH, et al. Value of nonvisualized primary lesions of gastric cancer on preoperative MDCT. Abdominal imaging. Original research. Am J Roentgenol. 2007; 189(6): W315–9. https://doi.org/10.2214/AJR.07.2672.</mixed-citation><mixed-citation xml:lang="en">Yu JS, Choi SH, Choi WH, et al. Value of nonvisualized primary lesions of gastric cancer on preoperative MDCT. Abdominal imaging. Original research. Am J Roentgenol. 2007; 189(6): W315–9. https://doi.org/10.2214/AJR.07.2672.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Ulla M, Gentile EM, Cavadas D, et al. Esophageal cancer characterization with pneumo-64-MDCT. Abdom Imaging. 2012; 37(4): 501–11. https://doi.org/10.1007/s00261-011-9784-z.</mixed-citation><mixed-citation xml:lang="en">Ulla M, Gentile EM, Cavadas D, et al. Esophageal cancer characterization with pneumo-64-MDCT. Abdom Imaging. 2012; 37(4): 501–11. https://doi.org/10.1007/s00261-011-9784-z.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Liu S, Shi H, Ji C, et al. Preoperative CT texture analysis of gastric cancer: correlations with postoperative TNM staging. Clin Radiol. 2018; 73(8): 756.e1–9. https://doi.org/10.1016/j.crad.2018.03.005.</mixed-citation><mixed-citation xml:lang="en">Liu S, Shi H, Ji C, et al. Preoperative CT texture analysis of gastric cancer: correlations with postoperative TNM staging. Clin Radiol. 2018; 73(8): 756.e1–9. https://doi.org/10.1016/j.crad.2018.03.005.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Nonaka K, Kita H. Endoscopic submucosal dissection for early gastric cancer. Journal of cancer therapy. 2013; 4(1A): 26–32. https://doi.org/10.4236/jct.2013.41A004.</mixed-citation><mixed-citation xml:lang="en">Nonaka K, Kita H. Endoscopic submucosal dissection for early gastric cancer. Journal of cancer therapy. 2013; 4(1A): 26–32. https://doi.org/10.4236/jct.2013.41A004.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Hwang SW, Lee DH, Lee SH, et al. Preoperative staging of gastric cancer by endoscopic ultrasonography and multidetector –row computed tomography. J Gastroenterol Hepatol. 2010; 25(3): 512–8. https://doi.org/10.1111/j.1440-1746.2009.06106.x.</mixed-citation><mixed-citation xml:lang="en">Hwang SW, Lee DH, Lee SH, et al. Preoperative staging of gastric cancer by endoscopic ultrasonography and multidetector –row computed tomography. J Gastroenterol Hepatol. 2010; 25(3): 512–8. https://doi.org/10.1111/j.1440-1746.2009.06106.x.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Ahn HS, Lee HJ, Yoo MW, et al. Diagnostic accuracy of T and N stages with endoscopy, stomach protocol CT, and endoscopic ultrasonography in early gastric cancer. J Surg Oncol. 2009; 99(1): 20–7. https://doi.org/10.1002/jso.21170.</mixed-citation><mixed-citation xml:lang="en">Ahn HS, Lee HJ, Yoo MW, et al. Diagnostic accuracy of T and N stages with endoscopy, stomach protocol CT, and endoscopic ultrasonography in early gastric cancer. J Surg Oncol. 2009; 99(1): 20–7. https://doi.org/10.1002/jso.21170.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Artifon EL, Marinho FR. Endoscopic screening for hereditary diffuse gastric cancer: one size does not fit all. Gastrointest Endosc. 2018; 87(2): 405–7. https://doi.org/10.1016/j.gie.2017.05.042.</mixed-citation><mixed-citation xml:lang="en">Artifon EL, Marinho FR. Endoscopic screening for hereditary diffuse gastric cancer: one size does not fit all. Gastrointest Endosc. 2018; 87(2): 405–7. https://doi.org/10.1016/j.gie.2017.05.042.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Quach DT, Hiyama T, Gotoda T. Identifying high-risk individuals for gastric cancer surveillance from western and eastern perspectives: lessons to learn and possibility to develop an integrated approach for daily practice. World J Gastroenterol. 2019; 25(27): 3546–62. https://doi.org/10.3748/wjg.v25.i27.3546.</mixed-citation><mixed-citation xml:lang="en">Quach DT, Hiyama T, Gotoda T. Identifying high-risk individuals for gastric cancer surveillance from western and eastern perspectives: lessons to learn and possibility to develop an integrated approach for daily practice. World J Gastroenterol. 2019; 25(27): 3546–62. https://doi.org/10.3748/wjg.v25.i27.3546.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Hijioka S, Chin K, Seto Y, et al. Eight-year survival after advanced gastric cancer treated with S-1 followed by surgery. World J Gastroenterol. 2010; 16(22): 2824–7. https://doi.org/10.3748/wjg.v16.i22.2824.</mixed-citation><mixed-citation xml:lang="en">Hijioka S, Chin K, Seto Y, et al. Eight-year survival after advanced gastric cancer treated with S-1 followed by surgery. World J Gastroenterol. 2010; 16(22): 2824–7. https://doi.org/10.3748/wjg.v16.i22.2824.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Aurello P, Berardi G, Antolino L, et al. Is a surgical approach justified in metachronous Krukenberg tumor from gastric cancer? A systematic review. Oncol Res Treat. 2018; 41(10): 644–9. https://doi.org/10.1159/000490956.</mixed-citation><mixed-citation xml:lang="en">Aurello P, Berardi G, Antolino L, et al. Is a surgical approach justified in metachronous Krukenberg tumor from gastric cancer? A systematic review. Oncol Res Treat. 2018; 41(10): 644–9. https://doi.org/10.1159/000490956.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Jung JO, Nienhüser H, Schleussner N, Schmidt T. Oligometastatic gastroesophageal adenocarcinoma: molecular pathophysiology and current therapeutic approach. Int J Mol Sc. 2020; 21(3): 951. https://doi.org/10.3390/ijms21030951.</mixed-citation><mixed-citation xml:lang="en">Jung JO, Nienhüser H, Schleussner N, Schmidt T. Oligometastatic gastroesophageal adenocarcinoma: molecular pathophysiology and current therapeutic approach. Int J Mol Sc. 2020; 21(3): 951. https://doi.org/10.3390/ijms21030951.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Giganti F, Orsenigo E, Arcidiacono PG, et al. Preoperative locoregional staging of gastric cancer: is there a place for magnetic resonance imaging? Prospective comparison with EUS and multidetector computed tomography. Gastric Cancer. 2016; 19(1): 216–25. https://doi.org/10.1007/s10120-015-0468-1.</mixed-citation><mixed-citation xml:lang="en">Giganti F, Orsenigo E, Arcidiacono PG, et al. Preoperative locoregional staging of gastric cancer: is there a place for magnetic resonance imaging? Prospective comparison with EUS and multidetector computed tomography. Gastric Cancer. 2016; 19(1): 216–25. https://doi.org/10.1007/s10120-015-0468-1.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
