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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rentrad</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник рентгенологии и радиологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of radiology and nuclear medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4676</issn><issn pub-type="epub">2619-0478</issn><publisher><publisher-name>Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20862/0042-4676-2021-102-2-116-123</article-id><article-id custom-type="elpub" pub-id-type="custom">rentrad-631</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Оценка эффективности ультраранней рентгенэндоваскулярной эмболизации церебральных аневризм при субарахноидальном кровоизлиянии</article-title><trans-title-group xml:lang="en"><trans-title>Evaluation of the Efficiency of Ultra-Early Endovascular Embolization of Cerebral Aneurisms in Subarachnoid Hemorrage</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9762-9723</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шалыгин</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shalygin</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p> ассистент кафедры лучевой диагностики; заведующий отделением </p><p>ул. Красный проспект, 52, Новосибирск, 630091, Российская Федерация</p><p>ул. Залесского, 6, Новосибирск, 630047, Российская Федерация</p></bio><bio xml:lang="en"><p> Assistant Professor, Chair of Radiation Diagnostics; Head of Department </p><p>Krasnyy prospekt, 52, Novosibirsk, 630091, Russian Federation</p><p>ul. Zalesskogo, 6, Novosibirsk, 630047, Russian Federation</p></bio><email xlink:type="simple">shalygin3@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4799-6338</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горбунов</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorbunov</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> д. м. н., профессор кафедры лучевой диагностики </p><p>ул. Красный проспект, 52, Новосибирск, 630091, Российская Федерация</p></bio><bio xml:lang="en"><p> Dr. Med. Sc., Professor, Chair of Radiation Diagnostics </p><p>Krasnyy prospekt, 52, Novosibirsk, 630091, Russian Federation</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8637-4083</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дергилев</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Dergilev</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p> д. м. н., профессор, заведующий кафедрой лучевой диагностики  </p><p>ул. Красный проспект, 52, Новосибирск, 630091, Российская Федерация</p></bio><bio xml:lang="en"><p> Dr. Med. Sc., Professor, Chief of Chair of Radiation Diagnostics </p><p>Krasnyy prospekt, 52, Novosibirsk, 630091, Russian Federation</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8656-7213</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ляшенко</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyashenko</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p> ассистент кафедры лучевой диагностики; врач отделения </p><p>ул. Красный проспект, 52, Новосибирск, 630091, Российская Федерация</p><p>ул. Залесского, 6, Новосибирск, 630047, Российская Федерация</p></bio><bio xml:lang="en"><p> Assistant Professor, Chair of Radiation Diagnostics; Radiologist </p><p>Krasnyy prospekt, 52, Novosibirsk, 630091, Russian Federation</p><p>ul. Zalesskogo, 6, Novosibirsk, 630047, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0810-4720</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сударкина</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sudarkina</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p> ассистент кафедры лучевой диагностики </p><p>ул. Красный проспект, 52, Новосибирск, 630091, Российская Федерация</p></bio><bio xml:lang="en"><p> Assistant Professor, Chair of Radiation Diagnostics </p><p>Krasnyy prospekt, 52, Novosibirsk, 630091, Russian Federation</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России;&#13;
ГБУЗ НСО «Городская клиническая больница № 1»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University;&#13;
City Clinical Hospital No. 1</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>09</day><month>06</month><year>2021</year></pub-date><volume>102</volume><issue>2</issue><fpage>116</fpage><lpage>123</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шалыгин К.В., Горбунов Н.А., Дергилев А.П., Ляшенко А.М., Сударкина А.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Шалыгин К.В., Горбунов Н.А., Дергилев А.П., Ляшенко А.М., Сударкина А.В.</copyright-holder><copyright-holder xml:lang="en">Shalygin K.V., Gorbunov N.A., Dergilev A.P., Lyashenko A.M., Sudarkina A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.russianradiology.ru/jour/article/view/631">https://www.russianradiology.ru/jour/article/view/631</self-uri><abstract><p> В обзоре обсуждается эффективность рентгенэндоваскулярной эмболизации интракраниальных аневризм при  субарахноидальном кровоизлиянии (САК) в первые 24 ч после  разрыва. Необходимость данного исследования продиктована  медико-социальной значимостью заболевания, в частности  высокой степенью летальности и инвалидизации при САК  аневризматического генеза, в том числе у молодых пациентов. Выбор сроков рентгенэндоваскулярной эмболизации при САК остается предметом дискуссии профессионального сообщества с момента внедрения метода в клиническую практику. Выполнение эмболизации в 1-е сутки с момента дебюта заболевания, так называемая ultra-early embolization  (ультраранняя эмболизация), потенциально положительно  влияет на исходы САК, снижая количество летальных случаев и увеличивая число благоприятных исходов. Основным преимуществом данной тактики является предотвращение повторного разрыва аневризмы, вероятность которого  наиболее высока в 1-е сутки заболевания, а также возможность начала интенсивной терапии САК в самые ранние сроки. </p></abstract><trans-abstract xml:lang="en"><p> The review discusses the effectiveness of endovascular embolization of intracranial aneurysms in subarachnoid hemorrhage (SAH) in the first 24 hours after rupture. The need for this study is dictated by the medical and social significance of the disease, in particular, the high degree of mortality and disability in SAH of aneurysmal origin, including in young patients. The choice of embolization timing for SAH remains a subject of discussion in the professional community since the introduction of the technique into clinical practice. Performing embolization on the first day after the onset of the  disease, the so-called “ultra-early embolization” has a potentially positive effect on the outcomes of SAH, reducing the number of deaths and increasing the number of favorable outcomes. The main advantage of this tactic is to prevent repeated rupture of the aneurysm, the probability of which is highest in the first day of  the disease, as well as the possibility of starting intensive therapy for SAH at the earliest possible time. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>убарахноидальное кровоизлияние</kwd><kwd>церебральная аневризма</kwd><kwd>ультраранняя эндоваскулярная эмболизация</kwd><kwd>обзор</kwd></kwd-group><kwd-group xml:lang="en"><kwd>subarachnoid hemorrhage</kwd><kwd>cerebral aneurysm</kwd><kwd>ultra-early endovascular embolization</kwd><kwd>review</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Connolly ES Jr, Rabinstein AA, Ricardo J, et al. Guidelines for the management of aneurysmal subarachnoid hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2012; 43(6): 1711–37. https://doi.org/10.1161/STR.0b013e3182587839.</mixed-citation><mixed-citation xml:lang="en">Connolly ES Jr, Rabinstein AA, Ricardo J, et al. Guidelines for the management of aneurysmal subarachnoid hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2012; 43(6): 1711–37. https://doi.org/10.1161/STR.0b013e3182587839.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Feigin VL, Lawes CM, Bennett DA, et al. Worldwide stroke incidence and early case fatality reported in 56 populationbased studies: a systematic review. Lancet Neurol. 2009; 8(4): 355–69. https://doi.org/10.1016/S1474-4422(09)70025-0.</mixed-citation><mixed-citation xml:lang="en">Feigin VL, Lawes CM, Bennett DA, et al. Worldwide stroke incidence and early case fatality reported in 56 populationbased studies: a systematic review. Lancet Neurol. 2009; 8(4): 355–69. https://doi.org/10.1016/S1474-4422(09)70025-0.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Hughes JD, Bond KM, Mekary RA, et al. Estimating the global incidence of aneurysmal subarachnoid hemorrhage: a systematic review for central nervous system vascular lesions and meta-analysis of ruptured aneurysms. World Neurosurg. 2018; 115: 430–47.e7. https://doi.org/10.1016/j.wneu.2018.03.220.</mixed-citation><mixed-citation xml:lang="en">Hughes JD, Bond KM, Mekary RA, et al. Estimating the global incidence of aneurysmal subarachnoid hemorrhage: a systematic review for central nervous system vascular lesions and meta-analysis of ruptured aneurysms. World Neurosurg. 2018; 115: 430–47.e7. https://doi.org/10.1016/j.wneu.2018.03.220.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Rinkel GJ, Djibuti M, Algra A, van Gijn J, et al. Prevalence and risk of rupture of intracranial aneurysms: a systematic review. Stroke. 1998; 29 (1): 251–6. https://doi.org/10.1161/01.str.29.1.251.</mixed-citation><mixed-citation xml:lang="en">Rinkel GJ, Djibuti M, Algra A, van Gijn J, et al. Prevalence and risk of rupture of intracranial aneurysms: a systematic review. Stroke. 1998; 29 (1): 251–6. https://doi.org/10.1161/01.str.29.1.251.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Nieuwkamp DJ, Setz LE, Algra A, et al. Changes in case fatality of aneurysmal subarachnoid haemorrhage over time, according to age, sex, and region: a meta-analysis. Lancet Neurol. 2009; 8(7): 635–42. https://doi.org/10.1016/S1474-4422(09)70126-7.</mixed-citation><mixed-citation xml:lang="en">Nieuwkamp DJ, Setz LE, Algra A, et al. Changes in case fatality of aneurysmal subarachnoid haemorrhage over time, according to age, sex, and region: a meta-analysis. Lancet Neurol. 2009; 8(7): 635–42. https://doi.org/10.1016/S1474-4422(09)70126-7.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Rackauskaite D, Svanborg E, Andersson E, et al. Prospective study: long-term outcome at 12–15 years after aneurysmal subarachnoid hemorrhage. Acta Neurol Scand. 2018; 138(5): 400–7. https://doi.org/10.1111/ane.12980.</mixed-citation><mixed-citation xml:lang="en">Rackauskaite D, Svanborg E, Andersson E, et al. Prospective study: long-term outcome at 12–15 years after aneurysmal subarachnoid hemorrhage. Acta Neurol Scand. 2018; 138(5): 400–7. https://doi.org/10.1111/ane.12980.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Xu Z, Rui YN, Hagan JP, Kim DH. Intracranial aneurysms: pathology, genetics, and molecular mechanisms. Neuromolecular Med. 2019; 21(4): 325–43. https://doi.org/10.1007/s12017-019-08537-7.</mixed-citation><mixed-citation xml:lang="en">Xu Z, Rui YN, Hagan JP, Kim DH. Intracranial aneurysms: pathology, genetics, and molecular mechanisms. Neuromolecular Med. 2019; 21(4): 325–43. https://doi.org/10.1007/s12017-019-08537-7.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Beck J, Rohde S, Berkefeld J, et al. Size and location of ruptured and unruptured intracranial aneurysms measured by 3-dimensional rotational angiography. Surg Neurol. 2006; 65(1): 18–25. https://doi.org/10.1016/j.surneu.2005.05.019.</mixed-citation><mixed-citation xml:lang="en">Beck J, Rohde S, Berkefeld J, et al. Size and location of ruptured and unruptured intracranial aneurysms measured by 3-dimensional rotational angiography. Surg Neurol. 2006; 65(1): 18–25. https://doi.org/10.1016/j.surneu.2005.05.019.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Fujii M, Yan J, Rolland WB, et al. Early brain injury, an evolving</mixed-citation><mixed-citation xml:lang="en">Fujii M, Yan J, Rolland WB, et al. Early brain injury, an evolving frontier in subarachnoid hemorrhage research. Transl Stroke Res. 2013; 4 (4): 432–46. https://doi.org/10.1007/s12975-013-0257-2.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">frontier in subarachnoid hemorrhage research. Transl Stroke Res. 2013; 4 (4): 432–46. https://doi.org/10.1007/s12975-013-0257-2.</mixed-citation><mixed-citation xml:lang="en">Macdonald RL. Delayed neurological deterioration after subarachnoid haemorrhage. Nat Rev Neurol. 2014; 10(1): 44–58. https://doi.org/10.1038/nrneurol.2013.246.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Macdonald RL. Delayed neurological deterioration after subarachnoid haemorrhage. Nat Rev Neurol. 2014; 10(1): 44–58. https://doi.org/10.1038/nrneurol.2013.246.</mixed-citation><mixed-citation xml:lang="en">Macdonald RL, Schweizer TA. Spontaneous subarachnoid haemorrhage. Lancet. 2017; 389(10069): 655–66. https://doi.org/10.1016/S0140-6736(16)30668-7.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Macdonald RL, Schweizer TA. Spontaneous subarachnoid haemorrhage. Lancet. 2017; 389(10069): 655–66. https://doi.org/10.1016/S0140-6736(16)30668-7.</mixed-citation><mixed-citation xml:lang="en">Garg R, Bar B. Systemic complications following aneurysmal subarachnoid hemorrhage. Curr Neurol Neurosci Rep. 2017; 17(1): 7. https://doi.org/10.1007/s11910-017-0716-3.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Garg R, Bar B. Systemic complications following aneurysmal subarachnoid hemorrhage. Curr Neurol Neurosci Rep. 2017; 17(1): 7. https://doi.org/10.1007/s11910-017-0716-3.</mixed-citation><mixed-citation xml:lang="en">Marcolini E, Hine J. Approach to the diagnosis and management of subarachnoid hemorrhage. West J Emerg Med. 2019; 20(2): 203–11. https://doi.org/10.5811/westjem.2019.1.37352.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Marcolini E, Hine J. Approach to the diagnosis and management of subarachnoid hemorrhage. West J Emerg Med. 2019; 20(2): 203–11. https://doi.org/10.5811/westjem.2019.1.37352.</mixed-citation><mixed-citation xml:lang="en">Cortnum S, Sorensen P, Jorgensen J. Determining the sensitivity of computed tomography scanning in early detection of subarachnoid hemorrhage. Neurosurgery. 2010; 66(5): 900–2.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Cortnum S, Sorensen P, Jorgensen J. Determining the sensitivity of computed tomography scanning in early detection of subarachnoid hemorrhage. Neurosurgery. 2010; 66(5): 900–2.</mixed-citation><mixed-citation xml:lang="en">Dubosh NM, Bellolio MF, Rabinstein AA, Edlow JA. Sensitivity of early brain computed tomography to exclude aneurysmal subarachnoid hemorrhage: a systematic review and metaanalysis. Stroke. 2016; 47(3): 750–5. https://doi.org/10.1161/STROKEAHA.115.011386.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Dubosh NM, Bellolio MF, Rabinstein AA, Edlow JA. Sensitivity of early brain computed tomography to exclude aneurysmal subarachnoid hemorrhage: a systematic review and metaanalysis. Stroke. 2016; 47(3): 750–5. https://doi.org/10.1161/STROKEAHA.115.011386.</mixed-citation><mixed-citation xml:lang="en">Verma RK, Kottke R, Andereggen L, et al. Detecting subarachnoid hemorrhage: comparison of combined FLAIR/SWI versus CT. Eur J Radiol. 2013; 82(9): 1539–45. https://doi.org/10.1016/j.ejrad.2013.03.021.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Verma RK, Kottke R, Andereggen L, et al. Detecting subarachnoid hemorrhage: comparison of combined FLAIR/SWI versus CT. Eur J Radiol. 2013; 82(9): 1539–45. https://doi.org/10.1016/j.ejrad.2013.03.021.</mixed-citation><mixed-citation xml:lang="en">McCormack RF, Hutson A. Can computed tomography angiography of the brain replace lumbar puncture in the evaluation of acute-onset headache after a negative noncontrast cranial computed tomography scan? Acad Emerg Med. 2010; 17(4): 444–51. https://doi.org/10.1111/j.1553-2712.2010.00694.x.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">McCormack RF, Hutson A. Can computed tomography angiography of the brain replace lumbar puncture in the evaluation of acute-onset headache after a negative noncontrast cranial computed tomography scan? Acad Emerg Med. 2010; 17(4): 444–51. https://doi.org/10.1111/j.1553-2712.2010.00694.x.</mixed-citation><mixed-citation xml:lang="en">Sailer AM, Wagemans BA, Nelemans PJ, et al. Diagnosing intracranial aneurysms with MR angiography: systematic review and meta-analysis. Stroke. 2014; 45(1): 119–26. https://doi.org/10.1161/STROKEAHA.113.003133.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Sailer AM, Wagemans BA, Nelemans PJ, et al. Diagnosing intracranial aneurysms with MR angiography: systematic review and meta-analysis. Stroke. 2014; 45(1): 119–26. https://doi.org/10.1161/STROKEAHA.113.003133.</mixed-citation><mixed-citation xml:lang="en">Stienen MN, Germans M, Burkhardt JK, et al. Predictors of in-hospital death after aneurysmal subarachnoid hemorrhage: analysis of a nationwide database (Swiss SOS [Swiss Study on Aneurysmal Subarachnoid Hemorrhage]). Stroke. 2018; 49(2): 333–40. https://doi.org/10.1161/STROKEAHA.117.019328.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Stienen MN, Germans M, Burkhardt JK, et al. Predictors of in-hospital death after aneurysmal subarachnoid hemorrhage: analysis of a nationwide database (Swiss SOS [Swiss Study on Aneurysmal Subarachnoid Hemorrhage]). Stroke. 2018; 49(2): 333–40. https://doi.org/10.1161/STROKEAHA.117.019328.</mixed-citation><mixed-citation xml:lang="en">Konovalov АN, Krylov VV, Filatov YuМ, et al. Recommendation protocol for the management of patients with subarachnoid hemorrhage. Proceedings of the VI Congress of Neurosurgeons of Russia. Novosibirsk; 2012 (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Коновалов А.Н., Крылов В.В., Филатов Ю.М. и др. Рекомендательный протокол ведения больных с субарахноидальным кровоизлиянием. Материалы VI Съезда нейрохирургов России. Новосибирск; 2012.</mixed-citation><mixed-citation xml:lang="en">Molyneux A, Kerr RS, Yu LM, et al. International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trial. Lancet. 2002; 360(9342): 1267–74. https://doi.org/10.1016/s0140-6736(02)11314-6.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Molyneux A, Kerr RS, Yu LM, et al. International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trial. Lancet. 2002; 360(9342): 1267–74. https://doi.org/10.1016/s0140-6736(02)11314-6.</mixed-citation><mixed-citation xml:lang="en">Phillips TJ, Dowling RJ, Yan B, et al. Does treatment of ruptured intracranial aneurysms within 24 hours improve clinical outcome? Stroke. 2011; 42(7): 1936–45. https://doi.org/10.1161/STROKEAHA.110.602888.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Phillips TJ, Dowling RJ, Yan B, et al. Does treatment of ruptured intracranial aneurysms within 24 hours improve clinical outcome? Stroke. 2011; 42(7): 1936–45. https://doi.org/10.1161/STROKEAHA.110.602888.</mixed-citation><mixed-citation xml:lang="en">Han Y, Ye F, Long X, et al. Ultra-early treatment for poor-grade aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis. World Neurosurg. 2018; 115: e160–71. https://doi.org/10.1016/j.wneu.2018.03.219.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Han Y, Ye F, Long X, et al. Ultra-early treatment for poor-grade aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis. World Neurosurg. 2018; 115: e160–71. https://doi.org/10.1016/j.wneu.2018.03.219.</mixed-citation><mixed-citation xml:lang="en">Gooderham PA, Steinberg GK. Reflections on the benefits and pitfalls of ultra-early aneurysm treatment after subarachnoid hemorrhage. /World Neurosurg. 2012; 77(2): 261–2. https://doi.org/10.1016/j.wneu.2011.10.049.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Gooderham PA, Steinberg GK. Reflections on the benefits and pitfalls of ultra-early aneurysm treatment after subarachnoid hemorrhage. /World Neurosurg. 2012; 77(2): 261–2. https://doi.org/10.1016/j.wneu.2011.10.049.</mixed-citation><mixed-citation xml:lang="en">Gu DQ, Zhang X, Luo B., et al. Impact of ultra-early coiling on clinical outcome after aneurysmal subarachnoid hemorrhage in elderly patients. Acad Radiol. 2012; 19(1): 3–7. https://doi.org/10.1016/j.acra.2011.09.012.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Gu DQ, Zhang X, Luo B., et al. Impact of ultra-early coiling on clinical outcome after aneurysmal subarachnoid hemorrhage in elderly patients. Acad Radiol. 2012; 19(1): 3–7. https://doi.org/10.1016/j.acra.2011.09.012.</mixed-citation><mixed-citation xml:lang="en">Luo YC, Shen CS, Mao JL, et al. Ultra-early versus delayed coil treatment for ruptured poor-grade aneurysm. Neuroradiology. 2015; 57(2): 205–10. https://doi.org/10.1007/s00234-014-1454-8.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Luo YC, Shen CS, Mao JL, et al. Ultra-early versus delayed coil treatment for ruptured poor-grade aneurysm. Neuroradiology. 2015; 57(2): 205–10. https://doi.org/10.1007/s00234-014-1454-8.</mixed-citation><mixed-citation xml:lang="en">Yao Z, Huab X, Ma L, et al. Timing of surgery for aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis. Int J Surg. 2017; 48: 266–74. https://doi.org/10.1016/j.ijsu.2017.11.033.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Yao Z, Huab X, Ma L, et al. Timing of surgery for aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis. Int J Surg. 2017; 48: 266–74. https://doi.org/10.1016/j.ijsu.2017.11.033.</mixed-citation><mixed-citation xml:lang="en">Qian Z, Peng T, Liu A, et al. Early timing of endovascular treatment for aneurysmal subarachnoid hemorrhage achieves improved outcomes. Curr Neurovasc Res. 2014; 11(1): 16–22. https://doi.org/10.2174/1567202610666131210104606.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Qian Z, Peng T, Liu A, et al. Early timing of endovascular treatment for aneurysmal subarachnoid hemorrhage achieves improved outcomes. Curr Neurovasc Res. 2014; 11(1): 16–22. https://doi.org/10.2174/1567202610666131210104606.</mixed-citation><mixed-citation xml:lang="en">Tykocki T, Czyż M, Machaj M, et al. Comparison of the timing of intervention and treatment modality of poor-grade aneurysmal subarachnoid hemorrhage. Br J Neurosurg. 2017; 31(4): 430–3. https://doi.org/10.1080/02688697.2017.1319906.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Tykocki T, Czyż M, Machaj M, et al. Comparison of the timing of intervention and treatment modality of poor-grade aneurysmal subarachnoid hemorrhage. Br J Neurosurg. 2017; 31(4): 430–3. https://doi.org/10.1080/02688697.2017.1319906.</mixed-citation><mixed-citation xml:lang="en">Zhao B, Rabinstein A, Murad MH, et al. Surgical and endovascular treatment of poor-grade aneurysmal subarachnoid hemorrhage: a systematic review and metaanalysis. J Neurosurg Sci. 2017; 61(4): 403–15. https://doi.org/10.23736/S0390-5616.16.03457-3.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Zhao B, Rabinstein A, Murad MH, et al. Surgical and endovascular treatment of poor-grade aneurysmal subarachnoid hemorrhage: a systematic review and metaanalysis. J Neurosurg Sci. 2017; 61(4): 403–15. https://doi.org/10.23736/S0390-5616.16.03457-3.</mixed-citation><mixed-citation xml:lang="en">Zhao B, Rabinstein A, Murad MH, et al. Surgical and endovascular treatment of poor-grade aneurysmal subarachnoid hemorrhage: a systematic review and metaanalysis. J Neurosurg Sci. 2017; 61(4): 403–15. https://doi.org/10.23736/S0390-5616.16.03457-3.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
