rentradВестник рентгенологии и радиологииJournal of radiology and nuclear medicine0042-46762619-0478Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists10.20862/0042-4676-2014-0-6-53-61rentrad-59Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEWS OF LITERATUREРОЛЬ ПОЗИТРОННОЙ ЭМИССИОННОЙ ТОМОГРАФИИ В ОЦЕНКЕ ГЕМОДИНАМИКИ ОПУХОЛЕЙ ГОЛОВНОГО МОЗГАROLE OF POSITRON EMISSION TOMOGRAPHY IN THE HEMODYNAMIC EVALUATION OF BRAIN TUMORSСтанжевскийА. А.StanzhevskiyA. A.

д. м. н., руководитель научно-организационного отдела, радиолог

пос. Песочный, ул. Ленинградская, 70, Санкт-Петербург, 197758

MD, PhD, DSc, Head of Scientific-organizational Department, Radiologist

poselok Pesochnyy, ul. Leningradskaya, 70, St. Petersburg, 197758

stanzhevsky@gmail.comПанфиленкоА. Ф.PanfilenkoA. F.

к. м. н., вед. науч. сотр. отдела лучевой диагностики

пос. Песочный, ул. Ленинградская, 70, Санкт-Петербург, 197758

MD, PhD, Leading Research Associate of Department of Radiology

poselok Pesochnyy, ul. Leningradskaya, 70, St. Petersburg, 197758

ТютинЛ. А.TyutinL. A.

д. м. н., профессор, руководитель отдела лучевой диагностики, заместитель директора по научной работе

пос. Песочный, ул. Ленинградская, 70, Санкт-Петербург, 197758

MD, PhD, DSc, Professor, Head of Department of Radiology, Deputy Director for Science

poselok Pesochnyy, ul. Leningradskaya, 70, St. Petersburg, 197758

ИлющенкоЮ. Р.IlyushchenkoYu. R.

науч. сотр. отдела лучевой диагностики 

пос. Песочный, ул. Ленинградская, 70, Санкт-Петербург, 197758

Research Associate of Department of Radiology 

poselok Pesochnyy, ul. Leningradskaya, 70, St. Petersburg, 197758

ФГБУ «Российский научный центр радиологии и хирургических технологий» Министерства здравоохранения РФРоссияRussian Research Center of Radiology and Surgical Technologies, Ministry of Health of the RFRussian Federation201402032016065361Copyright © Станжевский А.А., Панфиленко А.Ф., Тютин Л.А., Илющенко Ю.Р., 20162016Станжевский А.А., Панфиленко А.Ф., Тютин Л.А., Илющенко Ю.Р.Stanzhevskiy A.A., Panfilenko A.F., Tyutin L.A., Ilyushchenko Y.R.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.russianradiology.ru/jour/article/view/59

Представлен анализ литературы, посвященной использованию позитронной эмиссионной томографии (ПЭТ) с различными радиофармпрепаратами (РФП) в оценке мозгового кровотока, перфузии, а также состояния гематоэнцефалического барьера с целью изучения биологических свойств, диагностики, дифференциальной диагностики, стадирования и оценки эффективности лечения новообразований головного мозга. Детально описаны основные количественные показатели перфузии и мозгового кровотока, которые можно определять с помощью ПЭТ, представлено их сопоставление с морфологическими критериями оценки ангиогенеза и степени васкуляризации опухолевой ткани. 

The review analyzes the literature on the use positron emission tomography (PET) with various radiopharmaceuticals in the assessment of cerebral blood flow, perfusion, the blood-brain barrier in order to investigate the biological properties, diagnosis, differential diagnosis, staging of brain neoplasms and in the evaluation of the efficiency of their treatment. The main qualitative perfusion and cerebral blood flow indicators that can be identified by PET are described in detail and compared with morphological criteria for estimation of angiogenesis and the degree of tumor tissue vascularization.

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The authors declare that there are no conflicts of interest present.