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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rentrad</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник рентгенологии и радиологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of radiology and nuclear medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4676</issn><issn pub-type="epub">2619-0478</issn><publisher><publisher-name>Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20862/0042-4676-2019-100-6-339-346</article-id><article-id custom-type="elpub" pub-id-type="custom">rentrad-515</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Оценка диагностической ценности формы тройничных нервов и их нейроваскулярных взаимоотношений в диагностике тригеминальной невралгии</article-title><trans-title-group xml:lang="en"><trans-title>Estimation of the Diagnostic Value of the Shape of Trigeminal Nerves and Their Neurovascular Relationships in the Diagnosis of Trigeminal Neuralgia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3404-0548</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бакунович</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bakunovich</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бакунович Александр Владимирович, врач-рентгенолог</p><p>Иваньковское ш., 3, Москва, 125367</p></bio><bio xml:lang="en"><p>Aleksandr V. Bakunovich, Radiologist</p><p>Ivan'kovskoe shosse, 3, Moscow, 125367</p></bio><email xlink:type="simple">bioboi@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5649-2193</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синицын</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinitsyn</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Синицын Валентин Евгеньевич, д. м. н., профессор, заведующий кафедрой лучевой диагностики и лучевой терапии</p><p>Ломоносовский пр-т, 27, корп. 1, Москва, 119991</p></bio><bio xml:lang="en"><p>Valentin E. Sinitsyn, Dr. Med. Sc., Professor, Chief of Radiology and Radiotherapy Chair</p><p>Lomonosovskiy prospekt, 27, korpus 1, Moscow, 119991</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1266-4926</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мершина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mershina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мершина Елена Александровна, к. м. н., доцент кафедры лучевой диагностики и лучевой терапии</p><p>Ломоносовский пр-т, 27, корп. 1, Москва, 119991</p></bio><bio xml:lang="en"><p>Elena A. Mershina, Cand. Med. Sc., Associate Professor of Radiology and Radiotherapy Chair</p><p>Lomonosovskiy prospekt, 27, korpus 1, Moscow, 119991</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3157-6187</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Григорян</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Grigoryan</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Григорян Юрий Алексеевич, д. м. н., профессор, руководитель Центра нейрохирургии</p><p>Иваньковское ш., 3, Москва, 125367</p></bio><bio xml:lang="en"><p>Yuriy A. Grigoryan, Dr. Med. Sc., Professor, Head of Neurosurgery Center</p><p>Ivan'kovskoe shosse, 3, Moscow, 125367</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАУ «Лечебно-реабилитационный центр» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Center of Treatment and Rehabilitation, Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Московский государственный университет им. М.В. Ломоносова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Lomonosov Moscow State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>25</day><month>01</month><year>2020</year></pub-date><volume>100</volume><issue>6</issue><fpage>339</fpage><lpage>346</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бакунович А.В., Синицын В.Е., Мершина Е.А., Григорян Ю.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Бакунович А.В., Синицын В.Е., Мершина Е.А., Григорян Ю.А.</copyright-holder><copyright-holder xml:lang="en">Bakunovich A.V., Sinitsyn V.E., Mershina E.A., Grigoryan Y.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.russianradiology.ru/jour/article/view/515">https://www.russianradiology.ru/jour/article/view/515</self-uri><abstract><p>Цель исследования – оценить диагностическую ценность анатомических характеристик интрацистернальных порций тройничных нервов и прилежащих артерий в диагностике классической тригеминальной невралгии (ТН).</p><sec><title>Материал и методы</title><p>Материал и методы. При помощи изотропной МР-последовательности FIESTA проанализированы анатомические характеристики интрацистернальных порций тройничных нервов и прилежащих к ним артерий у 133 пациентов, включая 86 пациентов с клинически и хирургически верифицированной ТН (55±11 лет) и 47 пациентов группы контроля (51±16 лет). Измерялись площади сечения тройничных нервов в5 мм от моста мозга, отношения наибольшего инаименьшего диаметров нервов ваналогичных точках, расстояния до прилежащих артерий и расстояния между точкой теснейшего нейроваскулярного контакта имостом мозга. Длявсех параметров были построены характеристические кривые (ХК), выделены реперные точки c наибольшей специфичностью при приемлемом уровне чувствительности. Для каждой реперной точки определены показатели положительной и отрицательной прогностической ценности (ППЦ и ОПЦ).</p></sec><sec><title>Результаты</title><p>Результаты. Для отношений диаметров тройничных нервов вблизи от моста мозга площадь под ХК равнялась 0,77. При реперной точке 1,89 отношение чувствительность/специфичность (Ч/С) составило 0,57/0,82 с ППЦ 0,74 и ОПЦ 0,83. Площадь под кривой для площадей сечения тройничных нервов у моста мозга составила 0,76. Реперная точка при значении площади 3,65 мм2 дала отношение Ч/С 0,52/0,8 с ППЦ 0,51 и ОПЦ 0,91. Расстояние до прилежащей артерии дало площадь под ХК в 0,72. Отношение Ч/С при реперной точке 1,65 мм оказалось равно 0,53/0,789 при ППЦ 0,55 и ОПЦ 0,92. Площадь под ХК для расстояний между точкой нейроваскулярного конфликта и мостом мозга составила 0,75. Реперная точка в 4,05 мм при показателе Ч/С 0,6/0,78 характеризовалась ППЦ 0,77 и ОПЦ 0,94.</p></sec><sec><title>Заключение</title><p>Заключение. Все проанализированные анатомические параметры показали приемлемую диагностическую ценность при диагностике ТН. Определенные реперные значения параметров могут быть использованы в диагностике ТН с наибольшим приемлемым показателем специфичности при максимальной ОПЦ для снижения частоты ложноположительных результатов. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to estimate the diagnostic value of the anatomical characteristics of the intracisternal portions of the trigeminal nerves and adjacent arteries in diagnosing classical trigeminal neuralgia (TN).</p></sec><sec><title>Material and methods</title><p>Material and methods. Fast Imaging Employing Steady-state Acquisition (FIESTA) using an isotropic MRI sequence was used to analyze the anatomical characteristics of the intracisternal portions of the trigeminal nerves and adjacent arteries in 133 patients, including 86 patients aged 55±11 years with clinically and surgically verified TN and in 47 patients aged 51±16 years in the control group. The investigators measured the cross-sectional areas of the trigeminal nerves at 5 mm from the pons cerebelli, the ratio of the largest-to-smallest nerve diameters at similar points, the distance to the adjacent arteries, and that between the closest neurovascular contact (NVC) point and the pons cerebelli. Characteristic curves (CC) were constructed and reference points with the highest specificity were selected with an acceptable sensitivity level for all parameters. Positive and negative predictive values (PPV and NPV, respectively) are determined for each reference point.</p></sec><sec><title>Results</title><p>Results. The area under the CC was equal to 0.77 for the ratio to the diameters of the trigeminal nerves near the pons cerebelli. At a reference point of 1.89, the sensitivity/specificity (Se/Sp) ratio was 0.57/0.82 with a PPV of 0.74 and an NPV of 0.83. The area under the curve for the cross-sectional areas of the trigeminal nerves at the pons cerebelli was 0.76. The reference point with an area of 3.65 mm2 yielded a Se/Sp ratio of 0.52/0.8 with a PPV of 0.51 and an NPV of 0.91. The distance to the adjacent artery gave an area under the CC of 0.72. The Se/Sp ratio at a reference point of 1.65 mm turned out to be 0.53/0.789 at a PPV of 0.55 and an NPV of 0.92. The area under the CC for the distances between the NVC point and the pons cerebelli was 0.75. The reference point of 4.05 mm with a Se/Sp index of 0.6/0.78 was characterized by a PPV of 0.77 and an NPV of 0.94.</p></sec><sec><title>Conclusion</title><p>Conclusion. All the analyzed anatomical parameters showed an acceptable diagnostic value in diagnosing TN. Certain reference values of the parameters can be used to diagnose TN with the highest acceptable specificity at the maximum NPV to reduce frequent false-positive results. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>тригеминальная невралгия</kwd><kwd>магнитно-резонансная томография</kwd><kwd>FIESTA</kwd><kwd>морфометрия</kwd><kwd>тройничный нерв</kwd><kwd>нейроваскулярные взаимоотношения</kwd><kwd>чувствительность</kwd><kwd>специфичность</kwd><kwd>положительная прогностическая ценность</kwd><kwd>отрицательная прогностическая ценность</kwd><kwd>характеристическая кривая</kwd></kwd-group><kwd-group xml:lang="en"><kwd>trigeminal neuralgia</kwd><kwd>magnetic resonance imaging</kwd><kwd>FIESTA</kwd><kwd>morphometry</kwd><kwd>trigeminal nerve</kwd><kwd>neurovascular relationships</kwd><kwd>sensitivity</kwd><kwd>specificity</kwd><kwd>positive predictive value</kwd><kwd>negative predictive value</kwd><kwd>characteristic curve</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Antonini G., Di Pasquale A., Cruccu G., Truini A., Morino S., Saltelli G. et al. 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