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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rentrad</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник рентгенологии и радиологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of radiology and nuclear medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4676</issn><issn pub-type="epub">2619-0478</issn><publisher><publisher-name>Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20862/0042-4676-2014-0-5-34-39</article-id><article-id custom-type="elpub" pub-id-type="custom">rentrad-47</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>ВОЗМОЖНОСТИ КОМПЬЮТЕРНОЙ ТОМОГРАФИИ В ОЦЕНКЕ ПОЛИМОРФНЫХ ИЗМЕНЕНИЙ ПРИ ДЕСТРУКТИВНЫХ ПАНКРЕАТИТАХ</article-title><trans-title-group xml:lang="en"><trans-title>CAPABILITIES OF COMPUTED TOMOGRAPHY TO EVALUATE POLYMORPHIC CHANGES IN DESTRUCTIVE PANCREATITIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Касаткина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kasatkina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант</p><p>ImNeuenheimer Feld 110, 69120, Хайдельберг</p><p>ул. Баррикадная, 2/1, Москва, 123995</p><p>Иваньковское шоссе, 3, Москва, 125367</p></bio><bio xml:lang="en"><p>Postgraduate</p><p>ImNeuenheimer Feld 110, 69120, Heidelberg</p><p>ul. Barrikadnaya, 2/1, Moscow, 123995</p><p>Ivan’kovskoe shosse, 3, Moscow, 125367</p></bio><email xlink:type="simple">ekkasatkina@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Klauss</surname><given-names>M.</given-names></name><name name-style="western" xml:lang="en"><surname>Klauss</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., доцент</p><p>ImNeuenheimer Feld 110, 69120, Хайдельберг</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, Associate Professor</p><p>ImNeuenheimer Feld 110, 69120, Heidelberg</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Kauczor</surname><given-names>H.-U.</given-names></name><name name-style="western" xml:lang="en"><surname>Kauczor</surname><given-names>H.-U.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., профессор</p><p>ImNeuenheimer Feld 110, 69120, Хайдельберг</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, Professor</p><p>ImNeuenheimer Feld 110, 69120, Heidelberg</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ридэн</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Riden</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., профессор</p><p>ул. Баррикадная, 2/1, Москва, 123995</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, Professor</p><p>ul. Barrikadnaya, 2/1, Moscow, 123995</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Hackert</surname><given-names>T.</given-names></name><name name-style="western" xml:lang="en"><surname>Hackert</surname><given-names>T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., профессор</p><p>ImNeuenheimer Feld 110, 69120, Хайдельберг</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, Professor</p><p>ImNeuenheimer Feld 110, 69120, Heidelberg</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синицын</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinitsyn</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., профессор</p><p>ул. Баррикадная, 2/1, Москва, 123995</p><p>Иваньковское шоссе, 3, Москва, 125367</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, Professor</p><p>ul. Barrikadnaya, 2/1, Moscow, 123995</p><p>Ivan’kovskoe shosse, 3, Moscow, 125367</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Grenacher</surname><given-names>L.</given-names></name><name name-style="western" xml:lang="en"><surname>Grenacher</surname><given-names>L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., профессор</p><p>ImNeuenheimer Feld 110, 69120, Хайдельберг</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, Professor</p><p>ImNeuenheimer Feld 110, 69120, Heidelberg</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Университетская клиника г. Хайдельберг, &#13;
ГБОУ ДПО «Российская медицинская академия последипломного образования» Министерства здравоохранения РФ, &#13;
ФГБУ «Лечебно-реабилитационный центр» Министерства здравоохранения РФ</institution><country>Германия</country></aff><aff xml:lang="en"><institution>University Hospital of Surgery, &#13;
Russian Medical Academy of Postgraduate Education, Ministry of Health of the RF, &#13;
Federal Center of Treatment and Rehabilitation, Ministry of Health of the RF</institution><country>Germany</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Университетская клиника г. Хайдельберг</institution><country>Германия</country></aff><aff xml:lang="en"><institution>University Hospital of Surgery</institution><country>Germany</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБОУ ДПО «Российская медицинская академия последипломного образования» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Postgraduate Education, Ministry of Health of the RF</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГБОУ ДПО «Российская медицинская академия последипломного образования» Министерства здравоохранения РФ, &#13;
ФГБУ «Лечебно-реабилитационный центр» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Postgraduate Education, Ministry of Health of the RF, &#13;
Federal Center of Treatment and Rehabilitation, Ministry of Health of the RF</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>02</month><year>2016</year></pub-date><volume>0</volume><issue>5</issue><fpage>34</fpage><lpage>39</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Касаткина Е.А., Klauss M., Kauczor H., Ридэн Т.В., Hackert T., Синицын В.Е., Grenacher L., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Касаткина Е.А., Klauss M., Kauczor H., Ридэн Т.В., Hackert T., Синицын В.Е., Grenacher L.</copyright-holder><copyright-holder xml:lang="en">Kasatkina E.A., Klauss M., Kauczor H., Riden T.V., Hackert T., Sinitsyn V.E., Grenacher L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.russianradiology.ru/jour/article/view/47">https://www.russianradiology.ru/jour/article/view/47</self-uri><abstract><p>Цель исследования – определить, всегда ли зоны пониженной плотности в паренхиме поджелудочной железы (ПЖ), выявленные при компьютерно-томографическом (КТ) исследовании пациентов с острым панкреатитом, соответствуют участкам некроза железы, или данные изменения могут быть обратимыми.</p><sec><title>Материал и методы</title><p>Материал и методы. В исследование были включены 25 больных, у которых были проведены первичные КТ-исследования и КТ-исследования в динамике с различными временными промежутками. Два независимых исследователя с опытом работы 4 года и 19 лет ретроспективно проанализировали результаты обоих КТ-исследований. Прицельно оценивались размер (объем) и изменения КТ-плотности гиподенсных зон в паренхиме железы.</p></sec><sec><title>Результаты</title><p>Результаты. У 7 (28%) из 25 пациентов было отмечено повышение КТ-плотности в зонах, которые имели сниженную плотность при первичных КТ-исследованиях (повышение более чем на 30 HU расценивалось как значимое). Было выявлено статистически достоверное различие между группами пациентов при сравнении размеров гиподенсных зон (t-test: p=0,006, Mann–Whitney U-test: p=0,01) и разности КТ-плотности (t-test: p=0,00, Mann–Whitney U-test: p=0,00). Также определялась корреляция между размерами гиподенсных зон и разницей их КТ-плотности (Pearson: r=-0,533, p=0,006; Spearman: r=-0,636, p=0,001).</p></sec><sec><title>Заключение</title><p>Заключение. Результаты исследования позволяют предположить, что зоны с пониженной КТ-плотностью паренхимы поджелудочной железы не всегда соответствуют некротическим изменениям и могут быть обратимыми.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to determine whether the lower-density pancreatic parenchymal areas detected by a computed tomography (CT) study in patients with acute pancreatitis correspond to the necrotic portions of the gland or whether these changes may be reversal.</p></sec><sec><title>Material and methods</title><p>Material and methods. The investigation covered 25 patients who had undergone or dynamic CT studies made at different time intervals. Two independent investigators with 4 and 19 years of experience retrospectively analyzed the results of both CT studies. Target estimation was made of the extent (volume) of and CT density changes in the hypodense areas of the gland parenchyma.</p></sec><sec><title>Results</title><p>Results. Seven (28%) of the 25 patients were noted to have higher CT density in the areas that had decreased density during primary CT studies (more than a 30 HU increase was rated as significant). There was a statistically significant difference between the patient groups when comparing the extent of hypodense areas and the difference in CT density (t-test, p=0.006); Mann–Whitney U-test, p=0.01 for extent difference and t-test, p=0.00; Mann–Whitney U-test, p=0.00 for CT density difference. There was also a correlation between the extent of hypodense areas and the difference in their CT density (Pearson: r=-0.533, p=0.006; Spearman: r=-0.636, p=0.001).</p></sec><sec><title>Conclusion</title><p>Conclusion. The results of our investigation may suggest that the lower-density pancreatic parenchymal areas cannot always correspond to necrotic changes and may be reversible.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>острый панкреатит</kwd><kwd>некротический панкреатит</kwd><kwd>некроз поджелудочной железы</kwd><kwd>индекс тяжести</kwd><kwd>компьютерная томография</kwd><kwd>прогноз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute pancreatitis</kwd><kwd>necrotic pancreatitis</kwd><kwd>pancreatic necrosis</kwd><kwd>severity index</kwd><kwd>computed tomography</kwd><kwd>prognosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Balthazar E.J. Acute pancreatitis: assessment of severity with clinical and CT evaluation. Radiology. 2002; 223: 603–13.</mixed-citation><mixed-citation xml:lang="en">Balthazar E.J. 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