<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rentrad</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник рентгенологии и радиологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of radiology and nuclear medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4676</issn><issn pub-type="epub">2619-0478</issn><publisher><publisher-name>Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20862/0042-4676-2018-99-6-326-330</article-id><article-id custom-type="elpub" pub-id-type="custom">rentrad-400</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORTS</subject></subj-group></article-categories><title-group><article-title>Лучевая диагностика метастатического поражения легких при хориокарциноме матки</article-title><trans-title-group xml:lang="en"><trans-title>Radiologic diagnosis of pulmonary metastases of uterine choriocarcinoma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0810-4720</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сударкина</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sudarkina</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сударкина Анна Владимировна - врач-рентгенолог, ассистент кафедры лучевой диагностики.</p><p>Владимировский спуск, 2а, Новосибирск, 630003; Красный пр-т, 52, Новосибирск, 630091</p></bio><bio xml:lang="en"><p>Anna V. Sudarkina - Radiologist, Assistant Professor of Ohair of Radiology.</p><p>Vladimirovskiy spusk, 2а, Novosibirsk, 630003; Krasnyy Prospekt, 52, Novosibirsk, 630091 </p></bio><email xlink:type="simple">a.sudarkina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8637-4083</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дергилев</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Dergilev</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, заведующий отделением лучевой диагностики, заведующий кафедрой лучевой диагностики.</p><p>Владимировский спуск, 2а, Новосибирск, 630003; Красный пр-т, 52, Новосибирск, 630091</p></bio><bio xml:lang="en"><p>Dr. Med. Sc., Professor, Head of Department of Radiology; Chief of Chair of Radiology.</p><p>Vladimirovskiy spusk, 2а, Novosibirsk, 630003; Krasnyy Prospekt, 52, Novosibirsk, 630091</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6795-6678</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чикинев</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Chikinev</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, заведующий кафедрой госпитальной и детской хирургии.</p><p>Красный пр-т, 52, Новосибирск, 630091</p></bio><bio xml:lang="en"><p>Dr. Med. Sc., Professor, Chief of Chair of Hospital and Pediatric Surgery.</p><p>Krasnyy Prospekt, 52, Novosibirsk, 630091</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3690-1316</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дробязгин</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Drobyazgin</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор кафедры госпитальной и детской хирургии, торакальный хирург.</p><p>Красный пр-т, 52, Новосибирск, 630091</p></bio><bio xml:lang="en"><p>Dr. Med. Sc., Professor of Chair of Hospital and Pediatric Surgery, Thoracic Surgeon.</p><p>Krasnyy Prospekt, 52, Novosibirsk, 630091</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9517-6292</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кочура</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kochura</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, доцент кафедры лучевой диагностики, заведующий рентгеновским отделением.</p><p>Красный пр-т, 52, Новосибирск, 630091</p></bio><bio xml:lang="en"><p>Cand. Med. Sc., Associate Professor of Chair of Radiology, Head of Department of Roentgenology.</p><p>Krasnyy Prospekt, 52, Novosibirsk, 630091</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4799-6338</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горбунов</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorbunov</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, доцент кафедры лучевой диагностики.</p><p>Красный пр-т, 52, Новосибирск, 630091</p></bio><bio xml:lang="en"><p>Cand. Med. Sc., Associate Professor of Chair of Radiology.</p><p>Krasnyy Prospekt, 52, Novosibirsk, 630091</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НУЗ «Дорожная клиническая больница на ст. Новосибирск-Главный ОАО “РЖД”»; ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Railway Clinical Hospital on the Station Novosibirsk-Glavniy; Novosibirsk State Medical University, Minisrty of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University, Minisrty of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>02</day><month>01</month><year>2019</year></pub-date><volume>99</volume><issue>6</issue><fpage>326</fpage><lpage>330</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сударкина А.В., Дергилев А.П., Чикинев Ю.В., Дробязгин Е.А., Кочура В.И., Горбунов Н.А., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Сударкина А.В., Дергилев А.П., Чикинев Ю.В., Дробязгин Е.А., Кочура В.И., Горбунов Н.А.</copyright-holder><copyright-holder xml:lang="en">Sudarkina A.V., Dergilev A.P., Chikinev Y.V., Drobyazgin E.A., Kochura V.I., Gorbunov N.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.russianradiology.ru/jour/article/view/400">https://www.russianradiology.ru/jour/article/view/400</self-uri><abstract><p>Представлено клиническое наблюдение метастатического поражения легких при хориокарциноме матки, проявившегося кровохарканьем. Освещены сложности клинико-лучевой диагностики, обусловленные атипичной манифестацией хориокарциномы матки. Описаны семиотика метастатического поражения легких при хориокарциноме, вклад томографических методов исследования в диагностический процесс. Впервые использована диффузионно-взвешенная магнитно-резонансная томография грудной клетки для динамического наблюдения и выявления рецидива заболевания.</p><p>Случай представляет интерес в связи с необычной клинико-рентгенологической манифестацией хориокарциномы матки, позволяет повысить осведомленность врачей-рентгенологов о данной патологии, что поможет обеспечить ее раннюю диагностику и своевременное лечение.</p></abstract><trans-abstract xml:lang="en"><p>The article describes a rare case of metastatic pulmonary choriocarcinoma manifested with hemoptysis. Obstacles and pitfalls of the diagnosis of uterine choriocarcinoma with atypical manifestation were discussed. The patterns of pulmonary metastases of uterine choriocarcinoma and contribution of cross-sectional imaging modalities to diagnostic work-up were described. For the first time diffusion weighted magnetic resonance imaging of the chest was used for the follow-up examination and diagnosis of the recurrence of the disease.</p><p>This case is of interest due to unusual clinical and radiological presentation of uterine choriocarcinoma. The article is aimed to radiologists to be familiar with this disease to provide its early diagnosis and timely treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хориокарцинома</kwd><kwd>метастазы в легких</kwd><kwd>многосрезовая компьютерная томография</kwd><kwd>магнитно-резонансная томография</kwd><kwd>диффузионно-взвешенные изображения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>choriocarcinoma</kwd><kwd>pulmonary metastases</kwd><kwd>multislice computed tomography</kwd><kwd>magnetic resonance imaging</kwd><kwd>diffusion weighted imaging</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Мещерякова Л.А. Трофобластичес-кая болезнь. Опухоли женской репродуктивной системы. 2014; 4: 74-82.</mixed-citation><mixed-citation xml:lang="en">Meshcheryakova L.A. Trophoblastic disease. Opukholi Zhenskoy Reproduktiv-noy Sistemy (Tumors of Female Reproductive System). 2014; 4: 74-82 (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Mangla M., Singla D., Kaur H., Shar-ma S. Unusual clinical presentations of choriocarcinoma: a systematic review of case reports. TaiwanJ. Obstet. Gynecol. 2017; 56(1): 1-8. DOI: 10.1016/j.tjog.2015.05.011</mixed-citation><mixed-citation xml:lang="en">Mangla M., Singla D., Kaur H., Shar-ma S. Unusual clinical presentations of choriocarcinoma: a systematic review of case reports. TaiwanJ. Obstet. Gynecol. 2017; 56(1): 1-8. DOI: 10.1016/j.tjog.2015.05.011</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Тюрин И.Е. Лучевая диагностика метастатических поражений легких. Атмосфера. Пульмонология и аллергология. 2011; 1: 22-8.</mixed-citation><mixed-citation xml:lang="en">Tyurin I.E. Radiologic diagnosis of metastatic lung disease. Atmosfera. Pul'monologiya i Allergologiya (Atmosphere. Pulmonology and Allergology). 2011; 1: 22-8 (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Seo J.B., Im J.G., Goo J.M., Chung M.J., Kim M.Y. Atypical pulmonary metastases: spectrum of radiologic findings. Radiographics. 2001; 21 (2): 403-17. DOI: 10.1148/radiographics.21.2.g01mr17403</mixed-citation><mixed-citation xml:lang="en">Seo J.B., Im J.G., Goo J.M., Chung M.J., Kim M.Y. Atypical pulmonary metastases: spectrum of radiologic findings. Radiographics. 2001; 21 (2): 403-17. DOI: 10.1148/radiographics.21.2.g01mr17403</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Kani K.K., Lee J.H., Dighe M., Mo-shiri M., Kolokythas O., Dubinsky T. Gestatational trophoblastic disease: multimodality imaging assessment with special emphasis on spectrum of abnormalities and value of imaging in staging and management of disease. Curr. Probl. Diagn. Radiol. 2012; 41 (1): 1-10. DOI: 10.1067/j.cpradiol.2011.06.002</mixed-citation><mixed-citation xml:lang="en">Kani K.K., Lee J.H., Dighe M., Mo-shiri M., Kolokythas O., Dubinsky T. Gestatational trophoblastic disease: multimodality imaging assessment with special emphasis on spectrum of abnormalities and value of imaging in staging and management of disease. Curr. Probl. Diagn. Radiol. 2012; 41 (1): 1-10. DOI: 10.1067/j.cpradiol.2011.06.002</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Dhanda S., Ramani S., Thakur M. Gestational trophoblastic disease: a multimodality imaging approach with impact on diagnosis and management. Radiol. Res. Pract. 2014; 2014: 842751. DOI: 10.1155/2014/842751</mixed-citation><mixed-citation xml:lang="en">Dhanda S., Ramani S., Thakur M. Gestational trophoblastic disease: a multimodality imaging approach with impact on diagnosis and management. Radiol. Res. Pract. 2014; 2014: 842751. DOI: 10.1155/2014/842751</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Shaaban A.M., Rezvani M., Haro-un R.R., Kennedy A.M., Elsayes K.M., Olpin J.D. et al. Gestational trophoblastic disease: clinical and imaging features. Radiographics. 2017; 37: 681-700. DOI: 10.1148/rg.2017160140</mixed-citation><mixed-citation xml:lang="en">Shaaban A.M., Rezvani M., Haro-un R.R., Kennedy A.M., Elsayes K.M., Olpin J.D. et al. Gestational trophoblastic disease: clinical and imaging features. Radiographics. 2017; 37: 681-700. DOI: 10.1148/rg.2017160140</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Chang T.C., Yen T.C., Li Y.T., Wu Y.C., Chang Y.C., Ng K.K. et al. The role of 18F-fluorodeoxyglucose positron emission tomography in gestational trophoblastic tumours: a pilot study. Eur. J. Nucl. Med. Mol. Imaging. 2006; 33 (2): 156-63. DOI: 10.1007/s00259-005-1873-1</mixed-citation><mixed-citation xml:lang="en">Chang T.C., Yen T.C., Li Y.T., Wu Y.C., Chang Y.C., Ng K.K. et al. The role of 18F-fluorodeoxyglucose positron emission tomography in gestational trophoblastic tumours: a pilot study. Eur. J. Nucl. Med. Mol. Imaging. 2006; 33 (2): 156-63. DOI: 10.1007/s00259-005-1873-1</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
