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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rentrad</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник рентгенологии и радиологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of radiology and nuclear medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4676</issn><issn pub-type="epub">2619-0478</issn><publisher><publisher-name>Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20862/0042-4676-2014-0-4-13-19</article-id><article-id custom-type="elpub" pub-id-type="custom">rentrad-36</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>ПЕРВЫЙ ОПЫТ КОМБИНИРОВАННОГО ПРИМЕНЕНИЯ ЭЛАСТОГРАФИИ И ЭНДОБРОНХИАЛЬНОЙ УЛЬТРАСОНОГРАФИИ ПРИ ПАТОЛОГИИ СРЕДОСТЕНИЯ – ПРЕДВАРИТЕЛЬНАЯ ОЦЕНКА ОСУЩЕСТВИМОСТИ И СРАВНЕНИЕ ХАРАКТЕРИСТИК ПРИ РАЗЛИЧНЫХ ДОСТУПАХ</article-title><trans-title-group xml:lang="en"><trans-title>THE FIRST EXPERIENCE IN USING ELASTOGRAPHY IN COMBINATION WITH ENDOBRONCHIAL ULTRASONOGRAPHY FOR MEDIASTINAL PATHOLOGY: PRELIMINARY ASSESSMENT OF FEASIBILITY AND COMPARISON OF CHARACTERISTICS VIA DIFFERENT APPROACHES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сивокозов</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sivokozov</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-эндоскопист</p><p>Яузская аллея, 2, Москва, 107564</p></bio><bio xml:lang="en"><p>Endoscopist</p><p>Yauzskaya alleya, 2, Moscow, 107564</p></bio><email xlink:type="simple">grand63@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Силина</surname><given-names>Т. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Silina</surname><given-names>T. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-эндоскопист</p><p>Иваньковское шоссе, 3, Москва, 125367</p></bio><bio xml:lang="en"><p>Endoscopist</p><p>Ivan’kovskoe shosse, 3, Moscow, 125367</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Королев</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Korolev</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-эндоскопист</p><p>ул. Блюхера, 42, Челябинск, 454087</p></bio><bio xml:lang="en"><p>Endoscopist</p><p>ul. Blyukhera, 42, Chelyabinsk, 454087</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Праведников</surname><given-names>П. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pravednikov</surname><given-names>P. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-эндоскопист</p><p>пос. Истра, стр. 27, п/о Степановское, Красногорский район, Московская область, 143423</p></bio><bio xml:lang="en"><p>Endoscopist</p><p>poselok Istra, stroenie 27, Stepanovskoe, Krasnogorskiy rayon, Moscow oblast’, 143423</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ленский</surname><given-names>Б. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Lenskiy</surname><given-names>B. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>заведующий отделением эндоскопии </p><p>пос. Истра, стр. 27, п/о Степановское, Красногорский район, Московская область, 143423</p></bio><bio xml:lang="en"><p>Head of Department of Endoscopy </p><p>poselok Istra, stroenie 27, Stepanovskoe, Krasnogorskiy rayon, Moscow oblast’, 143423</p></bio><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Центральный научно-исследовательский институт туберкулеза» РАМН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central Research Institute of Tuberculosis, Russian Academy of Medical Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «Лечебно-реабилитационный центр» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Center of Treatment and Rehabilitation, Ministry of Health of the RF</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГЛПУ «Челябинский областной клинический онкологический диспансер» Министерства здравоохранения Челябинской области</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Chelyabinsk Regional Clinical Oncology Dispensary, Ministry of Health of the Chelyabinsk Region</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГУЗ «Московская городская онкологическая больница № 62» Департамента здравоохранения г. Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow City Oncology Hospital Sixty-Two, Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>27</day><month>02</month><year>2016</year></pub-date><volume>0</volume><issue>4</issue><fpage>13</fpage><lpage>19</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сивокозов И.В., Силина Т.Л., Королев В.Н., Праведников П.А., Ленский Б.С., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Сивокозов И.В., Силина Т.Л., Королев В.Н., Праведников П.А., Ленский Б.С.</copyright-holder><copyright-holder xml:lang="en">Sivokozov I.V., Silina T.L., Korolev V.N., Pravednikov P.A., Lenskiy B.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.russianradiology.ru/jour/article/view/36">https://www.russianradiology.ru/jour/article/view/36</self-uri><abstract><p>Цель исследования – провести предварительную оценку осуществимости эластографии при эндобронхиальной ультрасонографии и сравнить характеристики при различных доступах.</p><sec><title>Материал и методы</title><p>Материал и методы. В исследование включены 3 пациента со злокачественной, доброкачественной аденопатией средостения и паратрахеальной опухолью. Эластография выполнялась эхобронхоскопом Pentax EB-1970UK с помощью портативного ультразвукового сканера Hitachi Noblus. Всем пациентам проведена тонкоигольная аспирационная биопсия лимфатических узлов /образований средостения и легких иглами 22G (Cook, Medi-Globe). У одного пациента выполнено последовательное исследование одной и той же группы лимфоузлов из разного доступа (через пищевод и трахею) со сравнением характеристик.</p></sec><sec><title>Результаты</title><p>Результаты. Всего у 3 пациентов оценены 8 лимфоузлов и 1 паратрахеальное образование (группы 4L-7-4R-2R). Во всех случаях были получены воспроизводимые, приемлемые для визуальной оценки изображения. Стенка трахеи и бронхов не оказывала существенного негативного влияния на качество получаемого изображения. Наличие злокачественного поражения как лимфатических узлов, так и паратрахеального образования сочеталось со снижением эластичности тканей в зоне интереса. При оценке одного и того же добро- качественного лимфоузла из разных доступов было отмечено явное расхождение данных эластографии с резким снижением показателей эластичности при эндобронхиальном доступе.</p></sec><sec><title>Заключение</title><p>Заключение. Эластография при эндобронхиальной ультрасонографии технически осуществима. Стенка трахеи и бронхов не оказывает существенного влияния на качество получаемого изображения, данные эластографии воспроизводимы при повторных измерениях. Сравнение характеристик эластографии при различных доступах свидетельствует о тенденции к завышению данных о плотности лимфоузла при эндобронхиальном исследовании по сравнению с чреспищеводным доступом. Таким образом, прямой перенос накопленных данных и паттернов эластографической диагностики на эндобронхиальный доступ невозможен и, вероятно, потребует пересмотра критериев оценки злокачественности изменений при его использовании. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to preliminarily assess the feasibility of elastography in endobronchial ultrasonography and to compare characteristics via different accesses.</p></sec><sec><title>Material and methods</title><p>Material and methods. The investigation enrolled 3 patients (malignant, benign mediastinal adenopathy, paratracheal tumor). Elastography was carried out using a Pentax EB-1970UK echobronchoscope with a Hitachi Noblus ultrasound scanner. All the patients underwent fine-needle aspiration biopsy of mediastinal and pulmonary lymph nodes/masses with 22G needles (Cook, Medi-Globe). Sequential study of the same group of lymph nodes through different approaches through the esophagus and trachea was conducted, and its characteristics were compared in one patient.</p></sec><sec><title>Results</title><p>Results. A total of 8 lymph nodes and one paratracheal mass (Group 4L-7-4R-2R) were assessed in three patients. Reproducible images acceptable for visual assessment were obtained in all cases. The wall of the trachea and bronchi had no significant negative impact on the quality of an obtained image. Both malignant lesion of lymph nodes and paratracheal mass was accompanied by decreased tissue elasticity in the area of interest. Assessment of the same benign lymph node through different approaches revealed a clear discordance between elastographic findings with a drastic decrease in elasticity values via an endobronchial approach.</p></sec><sec><title>Conclusion</title><p>Conclusion. Endobronchial ultrasonography elastography is technically feasible. The wall of the trachea and bronchi has no significant impact on the quality of an obtained image; elastographic data are reproducible during re-measurements. Comparison of elastographic characteristics through different approaches suggests that there is a tendency to overestimate data on lymph node density during endobronchial examination versus a transesophageal approach. Thus, the direct transfer of the accumulated data and patterns of elastographic diagnosis to an endobronchial approach is impossible and likely to require a revision of criteria to estimate malignancy-associated changes during its application.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>рак легкого</kwd><kwd>саркоидоз</kwd><kwd>эндосонография</kwd><kwd>эластография</kwd><kwd>диагностика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>lung cancer</kwd><kwd>sarcoidosis</kwd><kwd>endosonography</kwd><kwd>elastography</kwd><kwd>diagnosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kinsey C.M., Arenberg D.A. Endobronchial ultrasound-guided transbronchial needle aspiration for non-small cell lung cancer staging. Am. J. Respir. Crit. Care Med. 2014; 189 (6): 640–9.</mixed-citation><mixed-citation xml:lang="en">Kinsey C.M., Arenberg D.A. 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