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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rentrad</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник рентгенологии и радиологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of radiology and nuclear medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4676</issn><issn pub-type="epub">2619-0478</issn><publisher><publisher-name>Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20862/0042-4676-2019-100-1-27-31</article-id><article-id custom-type="elpub" pub-id-type="custom">rentrad-349</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Толщина подкожно-жировой клетчатки плода как предиктор макросомии</article-title><trans-title-group xml:lang="en"><trans-title>Fetal Subcutaneous Fat Thickness as a Predictor of Macrosomia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3439-9753</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедева</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedeva</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лебедева Марина Андреевна - прикреплена к кафедре акушерства и гинекологии с курсом перинатологии для подготовки и защиты диссертации на соискание степени кандидата наук, МИ ФГА-ОУ ВО РУДН; врач ультразвуковой диагностики, ГКБ № 29 им. Н.Э. Баумана.</p><p>Госпитальная пл., 2, Москва, 111020; ул. Миклухо-Маклая, 6, Москва, 117198</p></bio><bio xml:lang="en"><p>Marina A. Lebedeva - PFUR; the Doctor of Ultrasonic Diagnostics, CCH No. 29 n.a. Bauman.</p><p>Hospitalnaya pl., 2, Moscow, 111020; Ul. Miklukho-Maklaya, 6, Moscow, 117198</p></bio><email xlink:type="simple">lebedevama@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7213-5981</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гагаев</surname><given-names>Ч. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Gagaev</surname><given-names>Ch. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гагаев Челеби Гасанович, доктор медицинских наук, доцент кафедры акушерства и гинекологии с курсом перинатологии МИ ФГА-ОУ ВО РУДН; врач УЗИ, акушер-гинеколог ГКБ № 29 им. Н.Э. Баумана.</p><p>Госпитальная пл., 2, Москва, 111020; ул. Миклухо-Маклая, 6, Москва, 117198</p></bio><bio xml:lang="en"><p>Chelebi G. Gagaev - MD, Associate Professor of Obstetrics Department of the Chair of Obstetrics and Gynecology with a Course of Perinatology, PFUR; Ultrasound Doctor, Obstetrician-Gynecologist, CCH No. 29 n.a. Bauman.</p><p>Hospitalnaya pl., 2, Moscow, 111020; Ul. Miklukho-Maklaya, 6, Moscow, 117198</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ Городская клиническая больница № 29 им. Н.Э. Баумана; Медицинский институт, ФГАОУ ВО Российский университет дружбы народов</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital No. 29 n.a. Bauman; Peoples’ Friendship University of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>14</day><month>03</month><year>2019</year></pub-date><volume>100</volume><issue>1</issue><fpage>27</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лебедева М.А., Гагаев Ч.Г., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Лебедева М.А., Гагаев Ч.Г.</copyright-holder><copyright-holder xml:lang="en">Lebedeva M.A., Gagaev C.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.russianradiology.ru/jour/article/view/349">https://www.russianradiology.ru/jour/article/view/349</self-uri><abstract><sec><title>Цель</title><p>Цель: оценить толщину подкожно-жировой клетчатки (ПЖК) плода по данным ультразвукового исследования. Провести анализ взаимосвязи толщины ПЖК, измеренной антенатально в различных локализациях и наличия макросомии плода.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Фетометрия проводилась 55 беременным: основная группа - беременные с сахарным диабетом различного типа - 54 (64%) и группа контроля - беременные без сахарного диабета 19 (56%). Помимо стандартных биометрических показателей у всех плодов была измерена толщина ПЖК в трех локализациях: в области средней трети плеча, бедра и передней брюшной стенки. В основной группе 11 детей родились с макросомией, в группе контроля - 5.</p></sec><sec><title>Результаты</title><p>Результаты. В основной группе вес новорожденных был достоверно выше по сравнению с контрольной группой: 5928 (545) г и 5458 (610) г соответственно, р=0,0056.</p><p>В контрольной группе наибольшей диагностической ценностью для прогнозирования рождения крупного плода оказалось измерение толщины ПЖК в области бедра, а в основной группе - соответственно в области плеча. Толщина ПЖК в области средней трети бедра 5 мм и более, в области средней трети плеча - 2,5 мм и более являются предикторами рождения крупного плода.</p></sec><sec><title>Заключение</title><p>Заключение. Определение предполагаемой массы плода по данным фетометрии чрезвычайно важно в акушерской практике, так как данное заключение может повлиять на сроки и способ родоразрешения. Основные формулы не всегда точны, особенно в случаях макросомии плода. Толщина ПЖК является дополнительным маркером макросомии и может быть использована даже в случаях затрудненной визуализации.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to estimate fetal subcutaneous fat (SCF) thickness, by using ultrasound findings. To analyze the relationship between the antenatal SCF thickness measurements at different sites and the presence of fetal macrosomia.</p></sec><sec><title>Material and methods</title><p>Material and methods. Fetometry was done in 53 pregnant women: a study group included 34 (64%) pregnant women with different types of diabetes mellitus and a control group consisted of 19 (36%) pregnant women without this condition. In addition to standard biometric parameters, SCF thickness was measured at three sites (mid-third of the shoulder, thigh, and anterior abdominal wall) in all fetuses. Eleven and three babies were born with macrosomia in the study and control groups, respectively.</p></sec><sec><title>Results</title><p>Results. The weight of newborns in the study group was significantly higher than that in the control group (3,928±543 and 3,458±610 g, respectively; p=0.0056).</p><p>The greatest diagnostic value in predicting a large fetus at birth was shown by SCF thickness measurements in the thigh area in the control group and in the shoulder area in the study group. The SCF thickness was 3 mm and more in the mid-third of the thigh and 2.5 mm and more in the mid-third of the shoulder, which are predictors of a large fetus.</p></sec><sec><title>Conclusions</title><p>Conclusions. Fetometric measurements of the estimated fetal weight are extremely important in obstetric practice, as this conclusion may affect delivery timing and mode. The basic formulas are not always accurate, especially in cases of fetal macrosomia. The SCF thickness is an additional marker for macrosomia and can be used even in cases of difficult visualization.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>макросомия</kwd><kwd>ультразвуковая фетометрия</kwd><kwd>предполагаемая масса плода</kwd><kwd>подкожно-жировая клетчатка</kwd></kwd-group><kwd-group xml:lang="en"><kwd>macrosomia</kwd><kwd>ultrasonic fetometry</kwd><kwd>estimated fetal mass</kwd><kwd>subcutaneous fatty tissue Conflict of interest: The authors declare no conflict of interest</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Warska A., Maliszewska A., Wnuk A., Szyszka B., Sawicki W., Cendrowski K. Current knowledge on the use of ultrasound measurements of fetal soft tissues for the assessment of pregnancy development. J Ultrason. 2018; 18(72): 50-5. DOI: 10.15557%2FJoU.2018.0008</mixed-citation><mixed-citation xml:lang="en">Warska A., Maliszewska A., Wnuk A., Szyszka B., Sawicki W., Cendrowski K. Current knowledge on the use of ultrasound measurements of fetal soft tissues for the assessment of pregnancy development. J Ultrason. 2018; 18(72): 50-5. DOI: 10.15557%2FJoU.2018.0008</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Chauhan S.P., West D.J., Scardo J.A., Boyd J.M., Joiner J., Hendrix N.W. Antepartum detection of macrosomic fetus: clinical versus sonographic, including soft-tissue measurements. Obstet Gynecol. 2000; 95(5): 639-42.</mixed-citation><mixed-citation xml:lang="en">Chauhan S.P., West D.J., Scardo J.A., Boyd J.M., Joiner J., Hendrix N.W. Antepartum detection of macrosomic fetus: clinical versus sonographic, including soft-tissue measurements. Obstet Gynecol. 2000; 95(5): 639-42.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Grivell R.M., Yelland L.N., Deussen A., Crowther C.A., Dodd J.M. Antenatal dietary and lifestyle advice for women who are overweight or obese and the effect on fetal growth and adiposity: the LIMIT randomised trial. BJOG. 2016; 123(2): 233-43. DOI: 10.1111/1471-0528.13777</mixed-citation><mixed-citation xml:lang="en">Grivell R.M., Yelland L.N., Deussen A., Crowther C.A., Dodd J.M. Antenatal dietary and lifestyle advice for women who are overweight or obese and the effect on fetal growth and adiposity: the LIMIT randomised trial. BJOG. 2016; 123(2): 233-43. DOI: 10.1111/1471-0528.13777</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Buhling K.J, Doll I., Siebert G., Catalano P.M. Relationship between sonographically estimated fetal subcutaneous adipose tissue measurements and neonatal skinfold measurements. Ultrasound Obstet Gynecol. 2012; 39: 558-62. DOI: 10.1002/uog.10092</mixed-citation><mixed-citation xml:lang="en">Buhling K.J, Doll I., Siebert G., Catalano P.M. Relationship between sonographically estimated fetal subcutaneous adipose tissue measurements and neonatal skinfold measurements. Ultrasound Obstet Gynecol. 2012; 39: 558-62. DOI: 10.1002/uog.10092</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Mintz M.C., Landon M.B., Gabbe S.G., Marinelli D.L., Ludmir J., Grumbach K. et al. Shoulder soft tissue thickness width a predictor of macrosomia in diabetic pregnancies. Am J Perinatol. 1989; 6: 240-3. DOI: 10.1159/000371628</mixed-citation><mixed-citation xml:lang="en">Mintz M.C., Landon M.B., Gabbe S.G., Marinelli D.L., Ludmir J., Grumbach K. et al. Shoulder soft tissue thickness width a predictor of macrosomia in diabetic pregnancies. Am J Perinatol. 1989; 6: 240-3. DOI: 10.1159/000371628</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Landon M.B., Sonek J., Foy P., Hamilton L., Gabbe S.G. Sonographic measurement of fetal humeral soft tissue thickness in pregnancy complicated by GDM. Diabetes. 1991; 40(Suppl. 2): 66-70.</mixed-citation><mixed-citation xml:lang="en">Landon M.B., Sonek J., Foy P., Hamilton L., Gabbe S.G. Sonographic measurement of fetal humeral soft tissue thickness in pregnancy complicated by GDM. Diabetes. 1991; 40(Suppl. 2): 66-70.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
