rentradВестник рентгенологии и радиологииJournal of radiology and nuclear medicine0042-46762619-0478Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists10.20862/0042-4676-2015-0-1-12-25rentrad-3Research ArticleСтатьиРегиональные аспекты исследования минеральной плотности кости методом рентгеновской денситометрии у женщинX-ray densitometry investigation of bone mineral density in women: Regional aspectsКолпинскийГ. И.KolpinskiyG. I.

д. м. н., главный врач, профессор кафедры лучевой диагностики, лучевой терапии и онкологии

MD, PhD, DSc, Head Physician, Professor of Department of Radiation Diagnosis, Radiotherapy and Oncology

ЗахаровИ. С.ZakharovI. S.

к. м. н., доцент кафедры акушерства и гинекологии № 1

MD, PhD, Associate Professor of Department of Obstetrics and Gynecology № 1

МБУЗ «Клинический консультативно-диагностический центр», ГБОУ ВПО «Кемеровская государственная медицинская академия» Министерства здравоохранения РФРоссияClinical Consultative and Diagnostic Center, Kemerovo State Medical Academy, Ministry of Health of the RFRussian FederationГБОУ ВПО «Кемеровская государственная медицинская академия» Министерства здравоохранения РФРоссияKemerovo State Medical Academy, Ministry of Health of the RFRussian Federation201527022016012226Copyright © Колпинский Г.И., Захаров И.С., 20162016Колпинский Г.И., Захаров И.С.Kolpinskiy G.I., Zakharov I.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.russianradiology.ru/jour/article/view/3

Цель исследования – на основании разработанной базы данных показателей  двухмерной минеральной плотности поясничных позвонков и проксимального отдела бедренной кости рассчитать Z-критерии для женщин различных возрастных групп Кемеровской области.Материал и методы. Проведен анализ результатов двухэнергетической рентгеновской абсорбциометрии поясничных позвонков и проксимального отдела бедренной кости 1504 здоровых женщин Кемеровской области.Результаты. Пиковые значения костной массы поясничного отдела позвоночника и проксимального отдела бедренной кости у женщин Кузбасса приходятся на возраст20–29 лет. Популяционные значения минеральной плотности кости (МПК) поясничных позвонков у женщин Кемеровской области имели достоверные отличия от таковых в базе данных NHANES III, начиная с 30-летнего возраста. Таким образом, разработанная база данных МПК имеет региональные особенности и должна быть использована для расчёта Z-критерия для популяции женщин Кузбасса. Учитывая, что не было выявлено различий пиковых значений костной массы у женщин двух  сравниваемых популяций, согласно рекомендациям Международного общества клинической денситометрии, для расчёта Т-критерия может быть использована база данных NHANES III.

Objective: to calculate Z scores for different age groups of women in the Kemerovo region, by relying on the developed database for two-dimensional bone mineral densities (BMD) of the lumbar vertebra and proximal femoral bone.Material and methods. This given investigation analyzed 1504 results of dual-energy X-ray absorptiometry of the lumbar vertebra and proximal femoral bone in healthy  women from the Kemerovo Region.Results. The performed investigation revealed that the peak bone mass of the lumbar spine and proximal femoral bone in the Kuzbass women corresponded to that of 20–29-year olds. In the women of the Kemerovo Region, the population-based lumbar vertebral BMDs significantly differed from those available in the NHANES III database starting from 30 years of age. Thus, the developed BMD database has regional features and must be used to calculate a Z score for the female population of Kuzbass. By taking into account the fact that were no differences in the peak body mass values of the women in the two compared groups in accordance of the guidelines of the International Society for Clinical  ensitometry; the NHANES III database may be used to estimate a T score.

остеопороздвухэнергетическая рентгеновская абсорбциометрияминеральная плотность костиosteoporosisdual-energy X-ray absorptionbone mineral densityReferencesHernlund E., Svedbom A., Ivergard M., Compston J. et. al. Osteoporosis in the European Union: medical management, epidemiology and economic burden. A report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA). Arch. Osteoporos. 2013; 8: 136.Hernlund E., Svedbom A., Ivergard M., Compston J. et. al. Osteoporosis in the European Union: medical management, epidemiology and economic burden. A report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA). Arch. Osteoporos. 2013; 8: 136.Lesnyak O.M. Osteoporosis audit in the Russian Federation. Profilakticheskaya meditsina. 2011; 2: 7–10 (in Russian).Lesnyak O.M. Osteoporosis audit in the Russian Federation. Profilakticheskaya meditsina. 2011; 2: 7–10 (in Russian).Baim S., Binkley N., Bilezikian J.P. et al. Official positions of the International Society for Clinical Densitometry and Executive Summary of the 2007 ISCD Position Development Conference. J. Clin. Densitom. 2008; 11 (1): 75–91.Baim S., Binkley N., Bilezikian J.P. et al. Official positions of the International Society for Clinical Densitometry and Executive Summary of the 2007 ISCD Position Development Conference. J. Clin. Densitom. 2008; 11 (1): 75–91.Kanis J.A. Assessment of bone mass. In: Assessment of osteoporosis. Ch. 3. Oxford: Blackwell Science; 1996: 226–78.Kanis J.A. Assessment of bone mass. In: Assessment of osteoporosis. Ch. 3. Oxford: Blackwell Science; 1996: 226–78.Lumbar spine and proximal femur bone mineral density, bone mineral content, and bone area: United States, 2005–2008. Data from the National Health and Nutrition Examination Survey (NHANES). Washington, DC, DHHS Publication №(PHS) 2012–1601. Series 11; 251.Lumbar spine and proximal femur bone mineral density, bone mineral content, and bone area: United States, 2005–2008. Data from the National Health and Nutrition Examination Survey (NHANES). Washington, DC, DHHS Publication №(PHS) 2012–1601. Series 11; 251.These are the Official Positions of the ISCD as updated in 2013. Available at: http://www.iscd.org/ official-positions/2013-iscd-officialpositionsadult (accessed April 24, 2014).These are the Official Positions of the ISCD as updated in 2013. Available at: http://www.iscd.org/ official-positions/2013-iscd-officialpositionsadult (accessed April 24, 2014).Lesnyak O.M., Benevolenskaya L.I. (eds) Osteoporosis. Moscow: GEOTAR-Media; 2009 (in Russian).Lesnyak O.M., Benevolenskaya L.I. (eds) Osteoporosis. Moscow: GEOTAR-Media; 2009 (in Russian).Kaptoge S., Reid D.M., ScheidtNave C. et al. Geographic and other determinants of BMD change in European men and women at the hip and spine. A population-based study from the Network in Europe for Male Osteoporosis (NEMO). Bone. 2007; 40 (3): 662–73.Kaptoge S., Reid D.M., ScheidtNave C. et al. Geographic and other determinants of BMD change in European men and women at the hip and spine. A population-based study from the Network in Europe for Male Osteoporosis (NEMO). Bone. 2007; 40 (3): 662–73.Glebova L.A., Kos'kina E.V., Bachina A.V., Chukhrov Yu.S. Risk for population health assessment in industrial centres of Kuzbass. Sanitarnyy vrach. 2013; 7: 61–3 (in Russian).Glebova L.A., Kos'kina E.V., Bachina A.V., Chukhrov Yu.S. Risk for population health assessment in industrial centres of Kuzbass. Sanitarnyy vrach. 2013; 7: 61–3 (in Russian).Paramonova E.S., Kos'kina E.V., Glebova L.A. Ecological and hygienic problems of the Kemerovo Region. Okhrana okruzhayushchey sredy i prirodopol'zovanie. 2013; 2: 42–5 (in Russian).Paramonova E.S., Kos'kina E.V., Glebova L.A. Ecological and hygienic problems of the Kemerovo Region. Okhrana okruzhayushchey sredy i prirodopol'zovanie. 2013; 2: 42–5 (in Russian).Hui S.L., Gao S., Zhou X.H., Johnston C.C. Jr, Lu Y., Gluer C.C. et al. Universal standardization of bone density measurements: a method with optimal properties for calibration among several instruments. J. Bone Miner. Res. 1997; 12: 1463–70.Hui S.L., Gao S., Zhou X.H., Johnston C.C. Jr, Lu Y., Gluer C.C. et al. Universal standardization of bone density measurements: a method with optimal properties for calibration among several instruments. J. Bone Miner. Res. 1997; 12: 1463–70.Zhang Z.-Q., Ho S.C., Chen Z.-Q., Zhang C.-X., Chen Y.-M. Reference values of bone mineral density and prevalence of osteoporosis in Chinese adults. Osteoporos Int. 2014; 25 (2): 497–507.Zhang Z.-Q., Ho S.C., Chen Z.-Q., Zhang C.-X., Chen Y.-M. Reference values of bone mineral density and prevalence of osteoporosis in Chinese adults. Osteoporos Int. 2014; 25 (2): 497–507.Lu Y., Fuerst T., Hui S., Genant H.K. Standardization of bone mineral density at femoral neck, trochanter and Ward's triangle. Osteoporos Int. 2001; 12: 438–44.Lu Y., Fuerst T., Hui S., Genant H.K. Standardization of bone mineral density at femoral neck, trochanter and Ward's triangle. Osteoporos Int. 2001; 12: 438–44.

The authors declare that there are no conflicts of interest present.