rentradВестник рентгенологии и радиологииJournal of radiology and nuclear medicine0042-46762619-0478Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists10.20862/0042-4676-2019-100-1-32-39rentrad-274Research ArticleОБЗОРЫREVIEWSСовременные тенденции лучевой диагностики лимфомы Ходжкина у детейCurrent Trends in the Radiodiagnosis of Hodgkin’s Lymphoma in Childrenhttps://orcid.org/0000-0001-6926-3165ХасановаК. А.KhasanovaK. A.

Хасанова Ксения Андреевна - аспирант.

Ул. Баррикадная, 2/1, Москва, 123995

Kseniya A. Khasanova – Postgraduate.

Ul. Barrikadnaya, 2/1, stroenie 1, Moscow, 125993

kkhas.ks@gmail.comhttps://orcid.org/0000-0003-3931-1431ТюринИ. Е.TyurinI. E.

Тюрин Игорь Евгениевич - доктор медицинских наук, профессор, заведующий кафедрой рентгенологии и радиологии.

Ул. Баррикадная, 2/1, Москва, 123995

Igor E. Tyurin - Dr. Med. Sc., Professor, Head of Department of Radiology and Nuclear Medicine.

Ul. Barrikadnaya, 2/1, stroenie 1, Moscow, 125993

ФГБОУДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава РоссииРоссияRussian Medical Academy of Continuing Professional Education, Ministry of Health of the Russian FederationRussian Federation20191403201910013239Copyright © Хасанова К.А., Тюрин И.Е., 20192019Хасанова К.А., Тюрин И.Е.Khasanova K.A., Tyurin I.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.russianradiology.ru/jour/article/view/274

Основными методами, применяемыми для первичного стадирования и оценки ответа на лечение у детей с лимфомой Ходжкина (ЛХ), являются компьютерная томография с контрастным усилением (КТ с КУ) и совмещенная позитронно-эмиссионная томография с 18F-фтордезокси-глюкозой с КТ (18F-ФДГ ПЭТ/КТ). Оба метода обладают высокими показателями чувствительности и специфичности. Несмотря на это, единый диагностический протокол для детей с лимфомой Ходжкина еще не разработан. Одновременное использование двух методик на каждом лечебном этапе не всегда является целесообразным. Необоснованное последовательное проведение КТ с КУ и ПЭТ/КТ с 18F-ФДГ у детей с ЛХ увеличивает кумулятивную дозу излучения на ребенка и расход ресурсов оборудования. В данной статье детально рассмотрены основные преимущества и недостатки методов КТ с КУ и ПЭТ/КТ с 18F-ФДГ на всех этапах ведения детей с ЛХ, а также освещены различные подходы к современным диагностическим алгоритмам при первичном стадировании ЛХ у детей и оценке эффективности лечения.

Поиск литературы осуществлялся с помощью следующих баз данных: Pubmed, Uptodate, CLinikaLKey, CyberLeninka, РИНЦ.

The main techniques used for the primary staging and evaluation of treatment response in children with Hodgkin's Lymphoma (HL) are contrast-enhanced computed tomography (CECT) and 18F-fl.uorodeoxygLucose positron emission tomography combined with computed tomography (18F-FDG PET/CT). Both techniques have a high sensitivity and specificity. Despite this, a single diagnostic protocol has not yet been developed for children with Hodgkin's Lymphoma. The simultaneous use of the two methods is not aLways appropriate at each treatment stage. The unreasonabLe consecutive performance of CECT and 18F-FDG PET/CT in children with HL increases the cumulative radiation dose for a child and the consumption of equipment resources. This article describes in detail the main advantages and disadvantages of CECT and 18F-FDG PET/CT at all stages of management of children with HL, as well as various approaches for current diagnostic algorithms in the primary staging of HL in children and in the evaluation of treatment efficiency.

Literature was sought using the following databases: Pubmed, Uptodate, ClinikalKey, CyberLen-inka, and Russian Science Citation Index (RSCI).

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The authors declare that there are no conflicts of interest present.