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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rentrad</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник рентгенологии и радиологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of radiology and nuclear medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4676</issn><issn pub-type="epub">2619-0478</issn><publisher><publisher-name>Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20862/0042-4676-2017-98-4-197-203</article-id><article-id custom-type="elpub" pub-id-type="custom">rentrad-253</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORTS</subject></subj-group></article-categories><title-group><article-title>ПРИМЕНЕНИЕ ДИФФУЗИОННО-ТЕНЗОРНЫХ ИЗОБРАЖЕНИЙ ДЛЯ ОЦЕНКИ ОТВЕТА НА СТЕРЕОТАКСИЧЕСКОЕ РАДИОХИРУРГИЧЕСКОЕ ЛЕЧЕНИЕ МЕТАСТАТИЧЕСКОГО ПОРАЖЕНИЯ ГОЛОВНОГО МОЗГА</article-title><trans-title-group xml:lang="en"><trans-title>ASSESSMENT OF METASTATIC BRAIN TUMORS RESPONSE TO STEREOTACTIC RADIOSURGERY WITH DIFFUSION TENSOR IMAGING</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8196-0518</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Токарев</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tokarev</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к. м. н., врач-нейрохирург, заведующий отделением «Центр радиохирургии»</p><p>Большая Сухаревская пл., 3, Москва, 129010, Российская Федерация</p></bio><bio xml:lang="en"><p>MD, PhD, Neurosurgeon, Head of Radiosurgery Department</p><p>Bol’shaya Sukharevskaya ploshchad’, 3, Moscow, 129010, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0007-8054</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Степанов</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Stepanov</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-рентгенолог</p><p>Большая Сухаревская пл., 3, Москва, 129010, Российская Федерация</p></bio><bio xml:lang="en"><p>Radiologist</p><p>Bol’shaya Sukharevskaya ploshchad’, 3, Moscow, 129010, Russian Federation</p></bio><email xlink:type="simple">mail@rssklif.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4534-8719</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рак</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Rak</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-нейрохирург</p><p>Большая Сухаревская пл., 3, Москва, 129010, Российская Федерация</p></bio><bio xml:lang="en"><p>Neurosurgeon</p><p>Bol’shaya Sukharevskaya ploshchad’, 3, Moscow, 129010, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ «Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского Департамента здравоохранения города Москвы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sklifosovsky Research Institute for Emergency Medicine, Moscow Health Department</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>06</day><month>09</month><year>2017</year></pub-date><volume>98</volume><issue>4</issue><fpage>197</fpage><lpage>203</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Токарев А.С., Степанов В.Н., Рак В.А., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Токарев А.С., Степанов В.Н., Рак В.А.</copyright-holder><copyright-holder xml:lang="en">Tokarev A.S., Stepanov V.N., Rak V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.russianradiology.ru/jour/article/view/253">https://www.russianradiology.ru/jour/article/view/253</self-uri><abstract><p>Одним из основных методов лечения множественного метастатического поражения головного мозга является лучевая терапия и такая ее современная разновидность, как стереотаксическое радиохирургическое лечение (СРХ). Применение СРХ у пациентов с метастатическим поражением головного мозга позволяет добиться локального контроля в 73–98% случаев (в зависимости от гистологического строения метастаза). Важнейшей задачей послеоперационного периода является оценка ответа опухоли на проведенное лечение и дифференцирование продолженного роста от лучевого некроза. В статье представлен клинический случай, демонстрирующий первый опыт использования диффузионно-тензорной магнитно-резонансной томографии для решения этой задачи.</p></abstract><trans-abstract xml:lang="en"><p>Metastatic brain tumors – one of the most actual problems of neurooncology. Currently, whole brain radiotherapy and stereotactic radiosurgery are the main treatment methods of this pathology. The assessment of tumor’s response to irradiation is very important issue in postoperative period. We attempted solve it by using diffusion tensor imaging.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>магнитно-резонансная томография</kwd><kwd>диффузионно-тензорные изображения</kwd><kwd>трактография</kwd><kwd>диффузия</kwd><kwd>гамма-нож</kwd><kwd>стереотаксическое радиохирургическое лечение</kwd><kwd>метастазы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>magnetic resonanse imaging</kwd><kwd>diffusion tensor imaging</kwd><kwd>tractography</kwd><kwd>diffusion</kwd><kwd>gamma-knife</kwd><kwd>stereotactic radiosurgery</kwd><kwd>metastases</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lippitz B., Lindquist C., Paddick I., Peterson D., O’Neill K., Beaney R. Stereotactic radiosurgery in the treatment of brain metastases: the current evidence. Cancer Treat. Rev. 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