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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rentrad</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник рентгенологии и радиологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of radiology and nuclear medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4676</issn><issn pub-type="epub">2619-0478</issn><publisher><publisher-name>Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20862/0042-4676-2017-98-1-17-22</article-id><article-id custom-type="elpub" pub-id-type="custom">rentrad-192</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>ЭФФЕКТИВНОСТЬ ПРИМЕНЕНИЯ КОЛИЧЕСТВЕННОГО АНАЛИЗА ДАННЫХ КОМПЬЮТЕРНОЙ ТОМОГРАФИИ ЛЕГКИХ У БОЛЬНЫХ ХРОНИЧЕСКОЙ ОБСТРУКТИВНОЙ БОЛЕЗНЬЮ ЛЕГКИХ</article-title><trans-title-group xml:lang="en"><trans-title>EFFICIENCY OF QUANTITATIVE ANALYSIS OF LUNG COMPUTED TOMOGRAPHY FINDINGS IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колсанов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolsanov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., профессор, заведующий кафедрой оперативной хирургии и клинической анатомии с курсом инновационных технологий</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, Professor, Head of Department of Operative Surgery and Clinical Anatomy Course with Innovative Technologies</p></bio><email xlink:type="simple">pzelter@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зельтер</surname><given-names>П. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Zel,ter</surname><given-names>P. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ассистент кафедры лучевой диагностики и лучевой терапии с курсом медицинской информатики</p></bio><bio xml:lang="en"><p>Assistant of Department of Radiology and Radiotherapy with a Course of Medical Informatics</p></bio><email xlink:type="simple">pzelter@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Капишников</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kapishnikov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., заведующий кафедрой лучевой диагностики и лучевой терапии с курсом медицинской информатики</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, Head of Department of Radiology and Radiotherapy with a Course of Medical Informatics</p></bio><email xlink:type="simple">pzelter@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чаплыгин</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Chaplygin</surname><given-names>S. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к. м. н., старший преподаватель кафедры оперативной хирургии и клинической анатомии с курсом инновационных технологий </p></bio><bio xml:lang="en"><p>MD, PhD, Senior Lecturer of Department of Operative Surgery and Clinical Anatomy Course with Innovative Technologies </p></bio><email xlink:type="simple">pzelter@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Самарский государственный медицинский университет» Минздрава России, ул. Чапаевская, 89, Самара, 443001, Российская Федерация</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State Medical University, Ministry of Health of the Russia, ul. Chapaevskaya, 89, Samara, 443001, Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>09</day><month>03</month><year>2017</year></pub-date><volume>98</volume><issue>1</issue><fpage>17</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Колсанов А.В., Зельтер П.М., Капишников А.В., Чаплыгин С.С., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Колсанов А.В., Зельтер П.М., Капишников А.В., Чаплыгин С.С.</copyright-holder><copyright-holder xml:lang="en">Kolsanov A.V., Zel,ter P.M., Kapishnikov A.V., Chaplygin S.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.russianradiology.ru/jour/article/view/192">https://www.russianradiology.ru/jour/article/view/192</self-uri><abstract><p>Цель исследования – оценить эффективность выявления эмфиземы при анализе томограмм легких с помощью программы «Автоплан» и сопоставить данные количественного анализа и клинические показатели. Материал и методы. Обследованы 60 больных хронической обструктивной болезнью легких, диагноз был подтвержден с помощью оценки функции внешнего дыхания, всем больным проведена инспираторно-экспираторная компьютерная томография на 32-рядном томографе с последующей постпроцессинговой обработкой в системе «Автоплан». Особенностями системы были плавающее пороговое значение, построение гистограммы, возможность сохранения отчета и полигональной модели. Эхокардиография выполнялась для оценки состояния правых отделов сердца и уровня давления в легочной артерии. Результаты. Получаемые числовые показатели оценки плотности легочной ткани (средняя плотность легочной ткани и индекс эмфиземы) продемонстрировали высокую эффективность (чувствительность до 78%, специфичность до 81%) в выявлении эмфиземы. Была доказана зависимость между данными количественного анализа и показателями функции внешнего дыхания. При анализе данных эхокардиографии выявлено влияние индекса эмфиземы на толщину стенки правого желудочка в систолу и диастолу (коэффициент Спирмена от –0,56 до –0,66). Заключение. Анализ плотностных характеристик легочной ткани при компьютерной томографии позволяет врачу получить объективные числовые показатели, которые могут влиять на прогрессирование обструктивных изменений у больных и развитие признаков хронического легочного сердца.</p><sec><title> </title><p> </p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to evaluate the efficiency of detection of emphysema in the analysis of lung computed tomography (CT) images using the “Autoplan” program and to compare the data of quantitative analysis and clinical indicators. Material and methods. Sixty patients with chronic obstructive pulmonary disease (COPD) were examined; the diagnosis was confirmed by external respiratory function evaluation; all the patients underwent inspiratory-expiratory CT using a 32-row multidetector CT scanner, followed by postprocessing in the “Autoplan” system. The features of the system were a floating threshold value, constructing a histogram, and the possibility of preserving a report and polygonal models. Echocardiography was performed to evaluate the right heart and to estimate pulmonary arterial pressure. Results. The obtained numerical values of lung density assessment (mean lung density and emphysema index) showed a high efficiency (a sensitivity of as high as 78%, a specificity of as high as 81%) in detecting emphysema. There was evidence for a relationship between the data of quantitative analysis and the values of external respiration function. Analysis of echocardiographic findings revealed that there was a relationship between emphysema index and systolic and diastolic right ventricle wall thickness (Spearman’s rank correlation coefficient from -0.56 to -0.66). Conclusion. Thus, analysis of the lung density CT characteristics provides a physician with objective numerical values, which affect the progression of obstructive changes in patients and the development of signs of chronic cor pulmonale.</p></sec><sec><title> </title><p> </p></sec><sec><title> </title><p> </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>компьютерная томография</kwd><kwd>хроническая обструктивная болезнь легких</kwd><kwd>эмфизема</kwd><kwd>количественный анализ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>computed tomography</kwd><kwd>chronic obstructive pulmonary disease</kwd><kwd>emphysema</kwd><kwd>quantitative analysis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Тюрин И.Е. Компьютерная томография органов грудной полости. СПб.: ЭЛБИ-СПб; 2003.</mixed-citation><mixed-citation xml:lang="en">Tyurin I.E. Computered tomography of thorax. St. Petersburg: ELBI-SPb; 2003 (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Труфанов Г.Е. Рентгеновская компьютерная томография в диагностике хронической обструктивной болезни легких. СПб.: ЭЛБИ-Пресс; 2009.</mixed-citation><mixed-citation xml:lang="en">Trufanov G.E. Computered tomography in COPD diagnostic. St. Petersburg: ELBI-Press; 2009 (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Зельтер П.М. Компьютерная томография в диагностике и фенотипировании хронической обструктивной болезни легких: Авто-реф. … канд. мед. наук. СПб.; 2016.</mixed-citation><mixed-citation xml:lang="en">Zel’ter P.M. Computered tomography in COPD diagnostic and pheno-typing: Сand. med. sci. Thesises of Diss. St. Petersburg; 2016 (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Hansell D.M., Bankier A.A., MacMahon H. et al. Fleischner Society: glossary of terms for thoracic imaging. Radiology. 2008; 246 (3): 697–722.</mixed-citation><mixed-citation xml:lang="en">Hansell D.M., Bankier A.A., Mac-Mahon H. et al. Fleischner Society: glossary of terms for thoracic imaging. Radiology. 2008; 246 (3): 697–722.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Xie X., de Jong P.A., Oudkerk M. et al. Morphological measurements in computed tomography correlate with airflow obstruction in chronic obstructive pulmonary disease: systematic review and meta-analysis. Eur. Radiol. 2012; 22: 2085–93.</mixed-citation><mixed-citation xml:lang="en">Xie X., de Jong P.A., Oudkerk M. et al. Morphological measurements in computed tomography correlate with airflow obstruction in chronic obstructive pulmonary disease: systematic review and meta-analysis. Eur. Radiol. 2012; 22: 2085–93.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Cohen J. Weighted kappa: nominal scale agreement with provision for scale disagreement or partial credit. Psychological Bulletin. 1968; 70 (4): 213–20.</mixed-citation><mixed-citation xml:lang="en">Cohen J. Weighted kappa: nominal scale agreement with provision for scale disagreement or partial credit. Psychological Bulletin. 1968; 70 (4): 213–20.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Boutou A.K., Nair A., Douraghi-Zadeh D. et al. A combined pulmonary function and emphysema score prognostic index for staging in chronic obstructive pulmonary disease. Plos one. 2014; 9 (Is. 10).</mixed-citation><mixed-citation xml:lang="en">Boutou A.K., Nair A., Douraghi-Zadeh D. et al. A combined pulmonary function and emphysema score prognostic index for staging in chronic obstructive pulmonary disease. Plos one. 2014; 9 (Is. 10).</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Muller N.L., Staples C.A., Miller R.R. et al. “Density mask”: an objective method to quantitate emphysema using computed tomography. Chest. 1988; 94 (4): 782–7</mixed-citation><mixed-citation xml:lang="en">Muller N.L., Staples C.A., Miller R.R. et al. “Density mask”: an objective method to quantitate emphysema using computed tomography. Chest. 1988; 94 (4): 782–7.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
