rentradВестник рентгенологии и радиологииJournal of radiology and nuclear medicine0042-46762619-0478Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists10.20862/0042-4676-2016-97-3-173-180rentrad-142Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEWS OF LITERATUREВопросы стандартизации метода нейротропной сцинтиграфии и однофотонной эмиссионной томографии миокарда с 123I-метайодбензилгуанидиномStandardization of 123I-metaiodobenzylguanidine cardiac neurotropic scintigraphy and single-photon emission tomographyАншелесА. А.AnshelesA. A.

к. м. н., ст. науч. сотр

MD, PhD, Senior Researcher

a.ansheles@gmail.comСергиенкоВ. Б.SergienkoV. B.

д. м. н., профессор, руководитель отдела радионуклидной диагностики и позитронно-эмиссионной томографии

MD, PhD, DSc, Professor, Head of Nuclear Medicine Department

ФГБУ «Российский кардиологический научно-производственный комплекс» Министерства здравоохранения РФ, ул. 3-я Черепковская, 15а, Москва, 121552, Российская ФедерацияРоссияRussian Cardiology Research-and-Production Complex, Ministry of Health of the RF, ul. Tret’ya Cherepkovskaya, 15a, Moscow, 121552, Russian FederationRussian Federation201620072016973173180Copyright © Аншелес А.А., Сергиенко В.Б., 20162016Аншелес А.А., Сергиенко В.Б.Ansheles A.A., Sergienko V.B.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.russianradiology.ru/jour/article/view/142

В обзоре приведены предпосылки к использованию в клинической практике метода радионуклидной диагностики нарушений симпатической активности миокарда с меченым метайодбензилгуанидином. По мере развития метода предлагались различные количественные параметры для оценки результатов его применения. Некоторые из них до сих пор вычисляются и трактуются по-разному в различных медицинских центрах. В обзоре систематизируются мировые данные, посвященные стандартизации метода и указываются факторы, препятствующие его единой валидации для клинических исследований.

Current review describes the prerequisites for clinical application of nuclear imaging with metaiodobenzylguanidine for cardiac sympathetic activity assessment. As the method developed, various quantitative parameters were proposed to evaluate its results. Some of them are still calculated and interpreted differently in various medical centers. This review systemizes the data regarding the attempts of method standardization, and describes factors that inhibit its validation for clinical trials.

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The authors declare that there are no conflicts of interest present.