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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rentrad</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник рентгенологии и радиологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of radiology and nuclear medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4676</issn><issn pub-type="epub">2619-0478</issn><publisher><publisher-name>Limited Liability Company "LUCHEVAYA DIAGNOSTIKA", Russian Association of Radiologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20862/0042-4676-2016-97-1-20-27</article-id><article-id custom-type="elpub" pub-id-type="custom">rentrad-101</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>ПРИМЕНЕНИЕ ФАЗОВО-КОНТРАСТНОЙ МАГНИТНО-РЕЗОНАНСНОЙ ТОМОГРАФИИ В КОЛИЧЕСТВЕННОЙ ОЦЕНКЕ ЛИКВОРОДИНАМИКИ У ПАЦИЕНТОВ С СООБЩАЮЩЕЙСЯ ГИДРОЦЕФАЛИЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>USE OF PHASE-CONTRAST MAGNETIC RESONANCE IMAGING TO QUANTIFY CEREBROSPINAL FLUID DYNAMICS IN PATIENTS WITH COMMUNICATING HYDROCEPHALUS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Богомякова</surname><given-names>О. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Bogomyakova</surname><given-names>O. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-рентгенолог, мл. науч. сотр.</p></bio><bio xml:lang="en"><p>Radiologist, Junior Research Associate</p></bio><email xlink:type="simple">bogom_o@tomo.nsc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Станкевич</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Stankevich</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-рентгенолог, мл. науч. сотр.</p></bio><bio xml:lang="en"><p>Radiologist, Junior Research Associate</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Месропян</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mesropyan</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>студентка</p></bio><bio xml:lang="en"><p>Student</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шрайбман</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shraybman</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-рентгенолог, мл. науч. сотр.</p></bio><bio xml:lang="en"><p>Radiologist, Junior Research Associate</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тулупов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tulupov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., гл. науч. сотр. МТЦ, зам. декана медицинского факультета, зам. директора Центра постдипломного медицинского образования, доцент кафедры фундаментальной медицины ННИГУ</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, Chief Research Associate of ITC, Deputy Dean of the Faculty of Medicine, Deputy Director of the Center of Postgraduate Medical Education, Associate Professor of Chair of Fundamental Medicine of NSU</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУН Институт «Международный томографический центр» Сибирского отделения Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute International Tomography Center of the Siberian Branch of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУН Институт «Международный томографический центр» Сибирского отделения Российской академии наук&#13;
ФГАОУ ВО «Новосибирский национальный исследовательский государственный университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute International Tomography Center of the Siberian Branch of the Russian Academy of Sciences&#13;
Novosibirsk State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>26</day><month>05</month><year>2016</year></pub-date><volume>97</volume><issue>1</issue><fpage>20</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Богомякова О.Б., Станкевич Ю.А., Месропян Н.А., Шрайбман Л.А., Тулупов А.А., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Богомякова О.Б., Станкевич Ю.А., Месропян Н.А., Шрайбман Л.А., Тулупов А.А.</copyright-holder><copyright-holder xml:lang="en">Bogomyakova O.B., Stankevich Y.A., Mesropyan N.A., Shraybman L.A., Tulupov A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.russianradiology.ru/jour/article/view/101">https://www.russianradiology.ru/jour/article/view/101</self-uri><abstract><p>Цель исследования – определить различия скоростных па- раметров потока ликвора у пациентов с разной степенью выраженности сообщающейся гидроцефалии (СГ) по сравнению с группой здоровых добровольцев без гидродинамических расстройств. Материал и методы. В исследовании приняли участие 27 пациентов с СГ (17 пациентов с индексом Эванса 0,31 и 10 пациентов с индексом Эванса 0,46) и 62 здоровых добровольца. Были определены средняя, объемная и пиковая ско- рости потока на различных интракраниальных уровнях. Результаты. Анализ различий между средними значе- ниями показал, что у пациентов с СГ наблюдается прогресси- рующее нарушение оттока спинномозговой жидкости из полости черепа, зависящее от степени выраженности расширения желудочковой системы и, вероятно, связанное с нарушением его обратного всасывания. Эти изменения могут объяснять клинические симптомы, имеющиеся у пациентов, а также служить диагностическими критериями. Заключение. Исследование показало возможности использования фазово-контрастной магнитно-резонансной томографии в оценке количественных параметров потока ликвора в условиях нормы и у пациентов с разной степенью выраженности сообщающейся гидроцефалии. Скоростные характеристики антеградного и ретроградного потоков ликвора достоверно отличаются в условиях нормы и патологии, что может быть актуально для неврологов и нейрохирургов при планировании терапевтического и хирургического лечения.</p><p> </p></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to determine differences in cerebrospinal fluid (CSF) flow velocities in patients with varying degrees of communicating hydrocephalus (CH) versus a group of healthy volunteers without hydrodynamic disorders. Material and methods. The investigation enrolled 27 CH patients (17 and 10 patients with an Evans index of 0.31 and 0.46, respectively) and 62 healthy volunteers. Average, volumetric, and peak flow velocities were determined at different intracranial levels. Results. Analysis of differences between the mean values indicated that the patients with CH were observed to have progressive cranial cavity CSF outflow obstruction that depended on the degree of dilation of the ventricular system and, probably, on impaired CSF reabsorption. These changes can provide an explanation for the clinical symptoms present in the patients and also serve as diagnostic criteria. Conclusion. The investigation showed that phase-contrast magnetic resonance imaging might be used to estimate the quantitative indicators of CSF in health and in varying degrees of CH. The velocity characteristics of antegrade and retrograde CSF flows are significantly different in health and in disease, which may be relevant to neurologists and neurosurgeons when planning therapy and surgery options.</p></sec><sec><title> </title><p> </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>магнитно-резонансная томография</kwd><kwd>центральная нервная система</kwd><kwd>цереброспинальная жидкость</kwd><kwd>сообщающаяся гидроцефалия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>magnetic resonance imaging</kwd><kwd>central nervous system</kwd><kwd>cerebrospinal fluid</kwd><kwd>communicating hydrocephalus</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование было поддержано грантом Российского научного фонда (проект № 14-35-00020)</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hakim S. 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